研究業績

英文

2023

1. Arakawa N, Yagi H, Shimizu M, Shigeta D, Shimizu A, Nomura S, Takizawa T, Yamada Y. Dupilumab Leads to Clinical Improvements including the Acquisition of Tolerance to Causative Foods in Non-Eosinophilic Esophagitis Eosinophilic Gastrointestinal Disorders.
Biomolecules. 2023: 13; 112-121.

2. Hagiwara SI, Hagiwara SI, Abe N, Hosoi K, Hara T, Ishige T, Shimizu H, Mizuochi T, Kakiuchi T, Kunisaki R, Matsuoka R, Kondou H, Kakuta F, Nakayama Y, Kimura T, Maeyama T, Honma H, Hirano D, Saruta M, Yoshida T, Okayasu I, Etani Y. Utility of a rapid assay for prostaglandin E-major urinary metabolite as a biomarker in pediatric ulcerative colitis. Sci Rep. 2023: 13; 9898.

3. Hara Y, Shiba N, Yoshida K, Yamato G, Kaburagi T, Shiraishi Y, Ohki K, Shiozawa Y, Kawamura M,Kawasaki H, Sotomatsu M, Takizawa T, Matsuo H,Shimada A, Kiyokawa N, Tomizawa D, Taga T, Ito E, Horibe K, Miyano S, Adachi S, Taki T, Ogawa S, Hayashi Y. TP53 and RB1 alterations characterize poor prognostic subgroups in pediatric acute myeloid
leukemia. Genes Chromosomes Cancer. 2023: 62; 412-422.

4. Ishige T, Shimizu T, Watanabe K, Arai K, Kame K, Kudo T, Kunisaki R, Tokuhara D, Naganuma M, Mizuochi T, Murashima A, Inoki Y, Iwata N, Iwama I, Koinuma S, Shimizu H, Jimbo K, Takaki Y, Takahashi S, Cho Y, Nambu R, Nishida D, Hagiwara SI, Hikita N, Fujikawa H, Hosoi K, Hosomi S, Mikami Y, Miyoshi J, Yagi R, Yokoyama Y, Hisamatsu T. Expert consensus on vaccination in patients with inflammatory bowel disease in Japan. J Gastroenterol. 2023: 58; 135-157.

5. Ito N, Kudo T, Eguchi H, Jimbo K, Furuhata A, Okuno T, Takeuchi I, Arai K, Ishige T, Okazaki Y, Shimizu T. Attenuated Expression of SLCO2A1 Caused by DNA Methylation in Pediatric Inflammatory Bowel Disease. Inflamm Bowel Dis. 2023: izad1116.

6. Kaburagi T, Shiba N, Yamato G, Yoshida K, Tabuchi K, Ohki K, Ishikita E, Hara Y, Shiraishi Y, Kawasaki H, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayahi Y. UBTF-Internal tandem duplication as a novel poor prognostic factor in pediatric acute myeloid leukemia. Genes Chromosomes Cancer. 2023: 62; 202-209.

7. Kato T, Miura M, Kobayashi T, Kaneko T, Fukushima N, Suda K, Maeda J, Shimoyama S, Shiono J, Hirono K, Ikeda K, Sato S, Numano F, Mitani Y, Waki K, Ayusawa M, Fukazawa R, Fuse S. Analysis of Coronary Arterial Aneurysm Regression in Patients With Kawasaki Disease by Aneurysm Severity: Factors Associated With Regression. J Am Heart Assoc. 2023: 12; e022417.

8. Minemura R, Sugitate R, Shimizu M, Murata T, Ishige T, Takizawa T. Trichorhinophalangeal syndrome type I associated with imperforate hymen. Pediatr Int. 2023: 65; e15679.

9. Mizuochi T, Iwama I, Inui A, Ito Y, Takaki Y, Mushiake S, Tokuhara D, Ishige T, Ito K, Murakami J, Hishiki H, Mikami H, Bessho K, Kato K, Yasuda R, Yamashita Y, Tanaka Y, Tajiri H. Real-world efficacy and safety of glecaprevir/pibrentasvir in Japanese adolescents with chronic hepatitis C: a prospective multicenter study. J Gastroenterol. 2023: 58; 405-412.
10. Mori H, Yoshikawa T, Kimura H, Ono H, Kato H, Ono Y, Nii M, Shindo T, Inuzuka R, Horigome H, Shiono J, Miura M, Hirono K, Kobayashi T, Kogaki S, Furutani Y, Nakanishi T. Outcomes of Hypertrophic Cardiomyopathy in Japanese Children: A Retrospective Cohort Study. Heart and Vessels. 2022: 37; 1075-1084.

11. Mori H, Sumitomo N, Tsutsui K, Ikeda K, et al. Efficacy of SubcutAneous implantable cardioVErterdefibrillators in≤18year-old CHILDREN: SAVECHILDREN registry. Int J Cardiol. 2023: 371; 204-210.

12. Nambu R, Arai K, Kudo T, Murakoshi T, Kunisaki R, Mizuochi T, Kato S, Kumagai H, Inoue M, Ishige T, Saito T, Noguchi A, Yodoshi T, Hagiwara SI, Iwata N, Nishimata S, Kakuta F, Tajiri H, Hiejima E, Toita N, Mochizuki T, Shimizu H, Iwama I, Hirano Y, Shimizu T; JPIBD-R. Clinical outcome of ulcerative colitis with severe onset in children: a multicenter prospective cohort study. J Gastroenterol. 2023: 58; 472-480.

13. Nishida Y, Yagi H, Ota M, Tanaka A, Sato K, Inoue T, Yamada S, Arakawa N, Ishige T, Kobayashi Y, Arakawa H, Takizawa T. Oxidative stress induces MUC5AC expression through mitochondrial damagedependent STING signaling in human bronchial epithelial cells. FASEB BioAdvances. 2023: 5; 171-181.

14. Nishimura A, Yokoyama K, Naruto T, Yamagishi C, Imamura T, Nakazono H, Kimura S, Ito M, Sagisaka M, Tanaka Y, Piao J, Namikawa Y, Yanagimachi M, Isoda T, Kanai A, Matsui H, Isobe T, Sato-Otsubo A, Higuchi N, Takada A, Okuno H, Saito S, Karakawa S, Kobayashi S, Hasegawa D, Fujisaki H, Hasegawa D, Koike K, Koike T, Rai S, Umeda K, Sano H, Sekinaka Y, Ogawa A, Kinoshita A, Shiba N, Miki M, Kimura F, Nakayama H, Nakazawa Y, Taga T, Taki T, Adachi S, Manabe A, Koh K, Ishida Y, Takita J, Ishikawa F, Goto H, Morio T, Mizutani S, Tojo A, Takagi M. Myeloid/natural killer (NK) cell precursor acute leukemia as a distinct leukemia type. Science advances. 2023: 9; 50.

15. Ota M, Nishida Y, Yagi H, Sato K, Yamada S, Arakawa H, Takizawa T. Regional differences in the prevalence of oral allergy syndrome among Japanese children: A questionnaire-based survey. Asian Pac J Allergy Immunol. 2023: 41; 142-149.

16. Shiga H, Takahashi T, Shiraki M, Kojima Y, Tsuji T, Takagi S, Hiramoto K, Yokoyama N, Sugimura M, Iwabuchi M, Endo K, Onodera M, Sato Y, Shimodaira Y, Nomura E, Kikuchi T, Chiba H, Oomori S, Kudo H, Kumada K, Nagaie S, Ogishima S, Nagami F, Shimoyama Y, Moroi R, Kuroha M, Kakuta Y, Ishige T, Kinouchi Y, Masamune A. Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents. Scand J Gastroenterol. 2023: 58; 360-367.

17. Shiga H, Takahashi T, Shiraki M, Kojima Y, Tsuji T, Takagi S, Hiramoto K, Yokoyama N, Sugimura M, Iwabuchi M, Endo K, Onodera M, Sato Y, Shimodaira Y, Nomura E, Kikuchi T, Chiba H, Oomori S, Kudo H, Kumada K, Nagaie S, Ogishima S, Nagami F, Shimoyama Y, Moroi R, Kuroha M, Kakuta Y, Ishige T, Kinouchi Y, Masamune A. Reduced antiviral seropositivity among patients with inflammatory bowel disease treated with immunosuppressive agents. Scand J Gastroenterol. 2023: 58; 360-367.

18. Takahashi S, Ishige T, Takizawa T. Methemoglobinemia Outbreak in a Neonatal ICU and Maternity Ward. New Eng J Med. 2023: 389; 2395-2397.

19. Takahashi Y, Fukuda H, Hayakawa A, Sano R, Kubo R, Kawabata-Iwakawa R, Nakajima T, Ishige T, Tokue H, Asano K, Seki T, Hsiao YY, Ishizawa F, Takei H, Kominato Y. Postmortem genetic analysis of 17 sudden cardiac deaths identified nonsense and frameshift variants in two cases of arrhythmogenic cardiomyopathy. Int J Legal Med. 2023: 137; 1927-
1937.

20. Urakawa T, Sano S, Kawashima S, Nakamura A, Shima H, Ohta M, Yamada Y, Nishida A, Narusawa H, Ohtsu Y, Matsubara K, Dateki S, Maruo Y, Fukami M, Ogata T, Kagami M. (Epi) genetic and clinical characteristics in 84 patients with pseudohypoparathyroidism type 1B. Eur J Endocrinol. 2023: 189; 590-600.

21. Watanabe A, Harimoto N, Saito H, Kawabata-Iwakawa R, Seki T, Muranushi R, Hoshino K, Hagiwara K, Ishii N, Tsukagoshi M, Igarashi T, Araki K, Ikota H, Ishige T, Mimori K, Shirabe K. Fibrolamellar hepatocellular carcinoma: a case report and gene analysis. Surg Case Rep. 2023: 9; 168.

22. Yagi N, Sugitate R, Shimizu M, Ogata T, Matusi A. Mild Encephalopathy with Reversible Splenic Lesions in an Infant with COVID-19 : MERS in an infant with COVID-19. J Nepal Paediatr. Soc. 2023: 43; 105-107.

23. Yokoyama K, Yamamoto Y, Nambu R, Hagiwara SI, Abukawa D, Mizuochi T, Kudo T, Sado T, Iwata N, Ishige T, Iwama I, Kumagai H, Arai K, Shimizu T. Safety and efficacy of vedolizumab in pediatric patients with ulcerative colitis: multicenter study in Japan. J Gastroenterol Hepatol. 2023: 38; 1107-1115.

2022

1. Adachi Y, Takizawa T, Futamura M, Fujisawa T, Yoshihara S; Committee for Japanese Pediatric Guideline for the Treatment and Management of Asthma; Japanese Society of Pediatric Allergy and Clinical Immunology; Japanese Society of Allergology. Executive summary: Japanese pediatric guideline for the treatment and management of asthma (JPGL) 2020. Allergol Int. 2022: 71; 472-480.

2. Hattori T, Notsu Y, Tanaka M, Matsui M, Iida T, Watanabe J, Osawa Y, Yamaguchi S, Yano S, Taketani T, Kobayashi H. A Simple Flow Injection Analysis-Tandem Mass Spectrometry Method to Reduce False Positives of C5-Acylcarnitines Due to Pivaloylcarnitine Using Reference Ions. Children. 2022: 9; 694.

3. Hoshino A, Toyofuku E, Mitsuiki N, Yamashita M, Okamoto K, Yamamoto M, Kanda K, Yamato G, Keino D, Yoshimoto-Suzuki Y, Kamizono J, Onoe Y, Ichimura T, Nagao M, Yoshimura M, Tsugawa K, Igarashi T, Mitsui-Sekinaka K, Sekinaka Y, Doi T, Yasumi T, Nakazawa Y, Takagi M, Imai K, Nonoyama S, Morio T, Latour S, Kanegane H. Clinical Courses of IKAROS and CTLA4 Deficiencies: A Systematic Literature Review and Retrospective Longitudinal Study. Front Immunol. 2022: 12; 784901.

4. Honzawa N, Fujimoto K, Kobayashi M, Kohno D, Kikuchi O, Hashimoto H, Wada E, Ikeuchi Y, Tabei Y, Gerald W. Dorn II,Utsunomiya K, Nishimura R and Kitamura T. Protein Kinase C (Pkc)-δ Mediates Arginine-Induced Glucagon Secretion in Pancreatic α-Cells. Int J Mol Sci. 2022: 23; 4003.

5. Iijima M, Stalll M, Wang L, Panetta JC, Triplett BM, Pui CH, Ribeiro RC, Rubnitz JE, Pounds SB, Inaba H. Changes in body mass index, weight, and height in children with acute myeloid leukemia and the associations with outcome. Blood Adv. 2022: 6; 2824-2834.

6. Imasawa T, Hirano D, Nozu K, Kimura H, Hattori M, Sugiyama H, SatoH and Murayama K; J-SMiN Collaborators. Clinicopathologic Features of Mitochondrial Nephropathy. Kidney Int Rep. 2022: 7; 580-590.

7. Ito K, Takizawa T. Nuclear Architecture in the Nervous System. Results Probl Cell Differ. 2022: 70; 419-442.

8. Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Tabuchi K, Shiraishi Y, Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y. Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica. 2022: 107; 583-592.

9. Kudo T, Jimbo K, Shimizu H, Iwama I, Ishige T, Mizuochi T, Arai K, Kumagai H, Uchida K, Abukawa D, Shimizu T. Qing-Dai for pediatric ulcerative colitis multicenter survey and systematic review. Pediatr Int. 2022: 64; e15113.

10. Miyamoto, T Honda Y, Izawa K, Kanazawa N,Kadowaki S, Ohnishi H, Fujimoto M, Kambe N, Kase N, Shiba T, Nakagishi Y, Akizuki S, Murakami K, Bamba M, Nishida Y, Inui A, Fujisawa T, Nishida D, Iwata N, Otsubo Y, Ishimori S, Nishikori M, Tanizawa K, Nakamura T, Ueda T, Ohwada Y, Tsuyusaki Y, Shimizu M, Ebato T, Iwao K, Kubo A, Kawai T, Matsubayashi T, Miyazaki T, Kanayama T, Nishitani-Isa M, Nihira H, Abe J, Tanaka T, Hiejima E, Okada S, Ohara O, Saito M. K, Takita J, Nishikomori R, Yasumi T. Assessment of type I interferon signatures in undifferentiated inflammatory diseases: A Japanese multicenter experience. Front Immunol. 2022: 13; doi: 10.3389/fimmu.2022.905960.

11. Morota J, Ishige T, Suzuki M, Igarashi Y, Takizawa T. Non-occlusive mesenteric ischemia in a toddler with 6q25 microdeletion syndrome. Pediatr Int. 2022: 64; e14751.

12. Nakamura-Utsunomiya A, Goda S, Hayakawa S, Sonoko S, Hoorn EJ, Blanchard A, Saito-Hakoda A, Kakimoto H, Hachiya R, Kamimura M, Kawakita R, Higuchi S, Fujimaru R, Shirai Y, Miyaoka D, Nagata Y, Kishi Y, Wada A, Mitsuboshi A, Ozaki K, Komatsu N, Niizuma H, Kanno J, Fujiwara I, Hasegawa Y, Yorifuji T, Brickman W, Vantyghem MC, Yamaguchi K, Goshima N, Hiyama TY. Identification of clinical factors related to antibody-mediated immune response to the subfornical organ. Clin Endocrinol (Oxf). 2022: 97; 72-80.

13. Osawa Y, Kobayashi H, Tajima G, Hara K, Yamada K, Fukuda S, Hasegawa Y, Aisaki J, Yuasa M, Hata I, Okada S, Shigematsu Y, Sasai H, Fukao T, Takizawa T, Yamaguchi S, Taketani T. The frequencies of very long-chain acyl-CoA dehydrogenase deficiency genetic variants in Japan have changed since the implementation of expanded newborn screening. Mol Genet Metab. 2022: 136; 74-79.

14. Rossanti R, Watanabe T, Nagano C, Hara S, Horinouchi T,Yamamura T, Sakakibara N, Ninchoji T, Iijima K, Nozu K. FAT1 biallelic truncating mutation causes a non‐syndromic proteinuria in a child. CEN Case Reports. 2021; 10: 100-105.

15. Sakamoto M, Iwama K, Sasaki M, Ishiyama A, Komaki H, Saito T, Takeshita E, Shimizu-Motohashi Y, Haginoya K, Kobayashi T, Goto T, Tsuyusaki Y, Iai M, Kurosawa K, Osaka H, Tohyama J, Kobayashi Y, Okamoto N, Suzuki Y, Kumada S, Inoue K, Mashimo H, Arisaka A, Kuki I, Saijo H, Yokochi K, Kato M, Inaba Y, Gomi Y, Saitoh S, Shirai K, Morimoto M, Izumi Y, Watanabe Y, Nagamitsu SI, Sakai Y, Fukumura S, Muramatsu K, Ogata T, Yamada K, Ishigaki K, Hirasawa K, Shimoda K, Akasaka M, Kohashi K, Sakakibara T, Ikuno M, Sugino N, Yonekawa T, Gürsoy S, Cinleti T, Kim CA, Teik KW, Yan CM, Haniffa M, Ohba C, Ito S, Saitsu H, Saida K, Tsuchida N, Uchiyama Y, Koshimizu E, Fujita A, Hamanaka K, Misawa K, Miyatake S, Mizuguchi T, Miyake N, Matsumoto N. Genetic and clinical landscape of childhood cerebellar hypoplasia and atrophy. Genet Med. 2022: 24; 2453-2463.

16. Shimoyama S, Takahashi D, Arai S, Asami Y, Nakajima K, Ikeda K, Takizawa T, Kobayashi T. A large amount of microscopic precipitates are inevitably injected during infusion therapy without an in-line filter. Oxf Med Case Reports. 2022: 2; 35-38.

17. Sugitate R, Muramatsu K, Ogata T, Goto M, Hayashi S, Sawaura N, Kawada-Nagashima M, Matsui A, Yamagata T. Recurrent pneumonia in three patients with MECP2 duplication syndrome with aspiration as the possible cause. Brain Dev. 2022: 44; 486-491.

18. Tajiri H, Suzuki M, Bessho K, Ito Y, Murakami J, Hatori R, Takano T, Miyoshi Y, Brooks S. The role of serum Wisteria floribunda agglutinin-positive Mac-2 binding protein in the assessment of fibrosis in children with chronic hepatitis C. Sci Rep. 2022: 12; 11205.

19. Takagi Y, Kobayashi Y, Hirakata A, Takei M, Ogasawara S, Yajima C, Ikeuchi Y, Matsumoto A, Ogawa Y, Handa H, Matsumoto M, Arakawa H, Takizawa T. Systemic Lupus Erythematosus Presenting with Thrombotic Thrombocytopenic Purpura at Onset: A Case Report. Front Pediatr. 2022: 10; 931669.

20. Yamato G, Kawai T, Shiba N, Ikeda J, Hara Y, Ohki K, Tsujimoto SI, Kaburagi T, Yoshida K, Shiraishi Y, Miyano S, Kiyokawa N, Tomizawa D, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Taga T, Horibe K, Ogawa S, Hata K, Hayashi Y. Genome-wide DNA methylation analysis in pediatric acute myeloid leukemia. Blood Adv. 2022: 6; 3207-3219.

21. Yamada K, Osawa Y, Kobayashi H, Bo R, Mushimoto Y, Hasegawa Y, Yamaguchi S, Taketani T. Clinical and molecular investigation of 37 Japanese patients with multiple acyl-CoA dehydrogenase deficiency: p.Y507D in ETFDH, a common Japanese variant, causes a mortal phenotype. Mol Genet Metab Rep. 2022: 33; 100940.

2021

・Egi M, Ogura H, Yatabe T, Shimoyama S, Nishida O, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020(J-SSCG 2020). Acute Med Surg. 2021: 26; e659.

・Egi M, Ogura H, Yatabe T, Shimoyama S, Nishida O, et al. The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020(J-SSCG 2020). J Intensive Care. 2021: 25; 53.

・Horikoshi T, Nishimura T, Nomura Y, Iwabuchi T, Itoh H, Takizawa T, Tsuchiya KJ. Umbilical cord serum concentrations of perfluorooctane sulfonate, perfluorooctanoic acid, and the body mass index changes from birth to 5 1/2 years of age. Sci Rep. 2021: 11; 19789.

・Iijima M, Liu W, Panetta JC, Hudson M, Pui CH, Srivastava DK, Krull KR, Inaba H. Association between obesity and neurocognitive function in survivors of childhood acute lymphoblastic leukemia treated only with chemotherapy. Cancer. 2021: 1; 3202-3213.

・Ikebe R, Kawaguchi A, Kawasaki T, Miura N, Matsuishi Y, Takeuchi M, Nittsu T, Fujiwara N, Shimoyama S, Nakayama Y, Akita C, Munekawa I, Kajinishi Y, Sasaki E, Sakamoto K, Matsuoka W. Physical Restraints in Critically Ill Children: A Multicenter Longitudinal Point Prevalence Study. Crit Care Med. 2021: 49; 1955-1962.

・Kaburagi T, Yamato G, Shiba N, Yoshida K, Hara Y, Tabuchi K, Shiraishi Y, Ohki K, Sotomatsu M, Arakawa H, Matsuo H, Shimada A, Taki T, Kiyokawa N, Tomizawa D, Horibe K, Miyano S, Taga T, Adachi S, Ogawa S, Hayashi Y. Clinical significance of RAS pathway alterations in pediatric acute myeloid leukemia. Haematologica. 2021: Online ahead of printdoi: 10.3324.

・Kameda T, Nakashima H, Takizawa T, Miura F, Ito T, Nakashima K, Imamura T. Neuronal activation modulates enhancer activity of genes for excitatory synaptogenesis through de novo DNA methylation. J Reprod Dev. 2021: Online ahead of print.

・Kuwajima M, Kojima K, Osaka H, Hamada Y, Jimbo E, Watanabe M, Aoki S, Sato-Shirai I, Ichimoto K, Fushimi T, Murayama K, Ohtake A, Kohda M, Kishita Y, Yatsuka Y, Uchino S, Mimaki M, Miyake N, Matsumoto N, Okazaki Y, Ogata T, Yamagata T, Muramatsu K. Valine metabolites analysis in ECHS1 deficiency. Mol Genet Metab Rep. 2021: 29; 100809.

・Leung ASY, Tham EH, Li J, Pacharn P, Takizawa T, Lee E, Xing Y, Leung TF, Hong SJ, Wong GWK. The role of the environment in shaping the trends of childhood asthma – An Asian perspective. Pediatr Allergy Immunol. 2021: 32; 1152-1164.

・Morota K, Shimizu M, Sugitate R, Ide M, Yamato G, Tomizawa D, Muramatsu K, Matsui A. Sudden unexpected death caused by infantile acute lymphoblastic leukaemia. Oxf Med Case Reports. 2021: 13; omab073.

・Nagasaki K, Nakamura A, Yamauchi T, Kamasaki H, Hara Y, Kanno J, Koyama S, Ohtsu Y, Takahashi I, Suzuki S, Kashimada K, Tajima T. Investigation of TSH receptor blocking antibodies in childhoodonset atrophic autoimmune thyroiditis. Clin Pediatr Endocrinol. 2021: 2; 79-84.

・Noguchi A, Ito K, Uosaki Y, Ideta-Otsuka M, Igarashi K, Nakashima H, Kakizaki T, Kaneda R, Uosaki H, Yanagawa Y, Nakashima K, Arakawa H, Takizawa T. Decreased Lamin B1 Levels Affect Gene Positioning and Expression in Postmitotic Neurons. Neurosci Res. 2021: Online ahead of print.

・Numaguchi A, Mizoguchi F, Aoki Y, An B, Ishikura A, Ichikawa K, Ito Y, Uchida Y, Umemoto M, Ogawa Y, Osamura T, Obonai M, Kaneko K, Kamizono J, Kizaki Z, Kinoshita A, Kurihara Y, Konishi N, Sato A, Shibano S, Senda M, Takizawa T, Nakabayashi Y, Nerome Y, Murata Y, Morisaki N, Yoshimura K, Kawano Y, Kobayashi M, Okumura A. Epidemiology of Child Mortality and Challenges in Child Death Review in Japan. Pediatr Int. 2021: Online ahead of print.

・Ohuchi H, Hayama Y, Nakajima K, Kurosaki K, Shiraishi I, Nakai M.Incidence, Predictors, and Mortality in Patients with Liver Cancer After Fontan Operation. J Am Heart Assoc. 2021:10;e016617.

・Onuki T, Ohtsu Y, Hiroshima S, Sawano K, Nagasaki K. Two cases of cytochrome P450 oxidoreductase deficiency with severe scoliosis and surgery requirement. Congenit Anom(Kyoto). 2021: 5; 202-203.

・Sasaki K, Tsujimoto S, Miyake M, Uchiyama Y, Ikeda J, Yoshitomi M, Shimosato Y, Tokumasu M, Matsuo H, Yoshida K, Ohki K, Kaburagi T, Yamato G, Hara Y, Takeuchi M, Kinoshita A, Tomizawa D, Taga T, Adachi S, Tawa A, Horibe K, Hayashi Y, Matsumoto N, Ito S, Shiba N. Droplet digital polymerase chain reaction assay for the detection of the minor clone of KIT D816V in paediatric acute myeloid leukaemia especially showing RUNX1-RUNX1T1 transcripts. Br J Haematol. 2021: 194; 414-422.

・Sasaki T, Ikeda K, Nakajima T, Kawabata-Iwakawa R, Iizuka T, Dharmawan T, Tamura S, Niwamae N, Tange S, Nishiyama M, Kaneko Y, Kurabayashi M. Multiple arrhythmic and cardiomyopathic phenotypes associated with an SCN5A A735E mutation. J Electrocardiol. 2021: 65; 122-127.

・Takagi Y, Miura K, Yabuuchi T, Kaneko N, Ishizuka K, Takei M, Yajima C, Ikeuchi Y, Kobayashi Y, Takizawa T, Hisano M, Tsurusaki Y, Matsumoto N, Hattori M. Any modality of renal replacement therapy can be a treatment option for Joubert syndrome. Sci Rep. 2021: 11; 1-17.

・Tatsuki M, Ishige T, Igarashi Y, Hatori R, Hokama A, Hirato J, Muise A, Takizawa T, Arakawa H. Whipple disease mimicking inflammatory bowel disease. Intest Res. 2021: 19; 119-125.

・Yamasaki Y, Kobayashi N, Akioka S, Yamazaki K, Takezaki S, Nakaseko H, Ohara A, Nishimura K, Nishida Y, Sato S, Kishi T, Hashimoto M, Mori M, Okazaki Y, Kuwana M, Ohta A. Clinical impact of myositis-specific autoantibodies on long-term prognosis of juvenile idiopathic inflammatory myopathies: multicentre study. Rheumatology(Oxford). 2021: 60; 4821-4831.

・Yamato G, Deguchi T, Terui K, Toki T, Watanabe T, Imaizumi T, Hama A, Iwamoto S, Hasegawa D, Ueda T, Yokosuka T, Tanaka S, Yanagisawa R, Koh K, Saito AM, Horibe K, Hayashi Y, Adachi S, Mizutani S, Taga T, Ito E, Watanabe K, Muramatsu H. Predictive factors for the development of leukemia in patients with transient abnormal myelopoiesis and Down syndrome. Leukemia. 2021: 35; 1480-1484.

・Yamato G, Park MJ, Sotomatsu M, Kaburagi T, Maruyama K, Kobayashi T, Nishi A, Sameshima K, Ohki K, Hayashi Y. Clinical features of 35 Down syndrome patients with transient abnormal myelopoiesis at a single institution. Int J Hematol. 2021: 113; 662-667.

・Yamazaki K, Ohta A, Akioka S, Yamasaki Y, Ohara A, Nakaseko H, Nishimura K, Kobayashi N, Nishida Y, Sato S, Takezaki S, Kishi T, Hashimoto M, Kobayashi I, Mori M. External validation of the EULAR/ACR idiopathic inflammatory myopathies classification criteria with a Japanese paediatric cohort. Rheumatology(Oxford). 2021: 60; 802-808.

2020

・Arai K, Kunisaki R, Kakuta F, Hagiwara SI, Murakoshi T, Yanagi T, Shimizu T,Kato S, Ishige T, Aomatsu T, Inoue M, Saito T, Iwama I, Kawashima H, Kumagai H, Tajiri H, Iwata N, Mochizuki T, Noguchi A, Kashiwabara T, Shimizu H, Suzuki Y, Hirano Y, Fujiwara T. Phenotypic characteristics of pediatric inflammatory bowel disease in Japan: results from a multicenter registry. Intest Res. 2020:18;412-420.

・Arakawa H, Adachi Y, Ebisawa M, Fujisawa T. On behalf of Committee for Japanese Pediatric Guideline for Childhood Asthma. Japanese guidelines for childhood asthma 2020. Allergol Int. 2020:69;314-330.

・Arakawa H, Shimojo N, Katoh N, Hiraba K, Kawada Y, Yamanaka K, Igawa K, Murota H, Okafuji I, Fukuie T, Nakahara T, Noguchi T, Kanakubo A, Katayama I. Consensus statements on pediatric atopic dermatitis from dermatology and pediatrics practitioners in Japan: Goals of treatment and topical therapy. Allergol Int. 2020:69;84-90.

・Fukahori S, Kawahara H, Oyama T, Saito T, Shimono R, Tanaka A, Noda T, Hatori R, Fujino J, Yagi M. Japanese Pediatric Impedance Working Group (Japanese-PIG). Standard protocol devised by the Japanese Pediatric Impedance Working Group for combined multichannel intraluminal impedance-pH measurements in children. Surg Today. 2020:50;664-671.

・Hara Y, Shiba N, Yamato G, Ohki K, Tabuchi K, Sotomatsu M, Tomizawa D, Kinoshita A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, Hayashi Y. Patients aged less than 3 years with acute myeloid leukaemia characterize a molecularly and clinically distinct subgroup. Br J Haematol. 2020:188;528-539.

・Izuminato Y, Nishigaki S, Satoh M, Takubo N, Numakura C, Takahashi I, Soneda S, Abe Y, Kamasaki H, Ohtsu Y, Igaki J, Hasegawa Y, Nagasaki K. Retrospective study of the renal function using estimated glomerular filtration rate and congenital anomalies of the kidney-urinary tract in pediatric Turner syndrome. Congenit Anom. 2020:60;175-179.

・Kato S, Shimizu T, Toyoda S, Gold BD, Ida S, Ishige T, Fujimura S, Kamiya S,Konno M, Kuwabara K, Ushijima K, Yoshimura N, Nakayama Y. Japanese Society for Pediatric Gastroenterology, Hepatology, Nutrition. The Updated JSPGHAN. Guidelines for the Management of Helicobacter pylori Infection in Childhood. Pediatr Int. 2020:62;1315-1331.

・Kobayashi I, Akioka S, Kobayashi N, Iwata N, Takezaki S, Nakaseko H Sato S, Nishida Y, Nozawa T, Yamasaki Y, Yamazaki K, Arai S, Nishino I, Mori M. Clinical practice guidance for juvenile dermatomyositis (JDM) 2018-Update. Mod Rheumatol. 2020:30;411-423.

・Koizumi A, Maruyama K, Ohki Y, Nakayama A, Yamada Y, Kurosawa H, Tsukagoshi H, Fujiu T, Takahashi M, Kimura T, Saruki N, Murakami M, Arakawa H. Prevalence and Risk Factor for Antibiotic-resistant Escherichia coli Colonization at Birth in Premature Infants: A Prospective Cohort Study. Pediatr Infect Dis J. 2020:39;546-552.

・Nakajima K, Seki M, Hatakeyama S, Arai S, Asami Y, Tanaka K, Ikeda K, Shimoyama S, Kobayashi T, Miyaomto T, Okada Y, Arakawa H, Takizawa T. Visual liver assessment using Gd-EOB-DTPA-enhanced magnetic resonance imaging of patients in the early post-Fontan period. Sci Rep. 2020:10;4909.

・Nishimura A, Yokoyama K, Yamagishi C, Imamura T, Naruto T, MorioT, Tanaka Y, Kanai A, Matsui H,Analysis Revealed Myeloid/Natural Killer (NK) Cell Precursor Acute Leukemia As a Novel Distinctive Okuno H, Taki T, Adachi S, Manabe A, Koh K, Ishida Y, Tojo A, Takagi A. Comprehensive Genetic Leukemia Entity. Blood. 2020:136;14-15.

・Ogata T, Muramatsu K, Miyana K, Ozawa H, Iwasaki M, Arakawa H. Neurodevelopmental outcome and respiratory management of congenital central hypoventilation syndrome: a retrospective study. BMC Pediatr. 2020:20;342.

・Ohki K, Takahashi H, Fukushima T, Nanmoku T, Kusano S, Mori M, Nakazawa Y, Yuza Y, Migita M, Okuno H, Morimoto A, Yoshino H, Kato M, Hayashi Y, Manabe A, Ohara A, Hasegawa D, Inukai T, Tomizawa D, Koh K, Kiyokawa N. Impact of immunophenotypic characteristics on genetic subgrouping in childhood acute lymphoblastic leukemia: Tokyo Children’s Cancer Study Group (TCCSG) study L04-16. Genes Chromosomes Cancer. 2020:59;551-561.

・Osawa Y, Wada A, Ohtsu Y, Yamada K, Takizawa T. Late-onset argininosuccinic aciduria associated with hyperammonemia triggered by influenza infection in an adolescent: A case report. Mol Genet Metab Rep. 2020:24; 100605.

・Ota M, Nishida Y, Yagi H, Sato K, Yamada S, Arakawa H, Takizawa T. Regional differences in the prevalence of oral allergy syndrome among Japanese children: A questionnaire-based survey. Asian Pac J Allergy Immunol. 2020: DOI 10. 12932/AP-130120-0739.

・Shimokawa C, Kato T, Takeuchi T, Ohshima N, Furuki T, Ohtsu Y, Suzue K, Imai T, Obi S, Olia A, Izumi T, Sakurai M, Arakawa H, Ohno H, Hisaeda H. CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes. Nat Commun. 2020:11;1922.

・Sugitate R, Okubo Y, Nariai H, Matsui A. The effects of antihistamine on the duration of the febrile seizure: A single center study with a systematic review and meta-analysis. Brain Dev. 2020:42; 103-112.

・Sunaga Y, Muramatsu K, Kosaki K, Sugai K, Mizuno T, Kouno M, Tashiro M. Variant in the neuronal vesicular SNARE VAMP2 (synaptobrevin-2): First report in Japan. Brain Dev. 2020: 42;529-533.

・Tatsuki M, Hatori R, Nakazawa T, Ishige T, Hara T, Kagimoto S, Tomomasa T, Arakawa H, Takizawa T. Serological cytokine signature in paediatric patients with inflammatory bowel disease impacts diagnosis. Sci Rep. 2020:10;1-11.

・Uchida T, Suzuki T, Kikuchi A, Kakuta F, Ishige T, Nakayama Y, Kanegane H, Etani Y, Mizuochi T, Fujiwara SI, Nambu R, Suyama K, Tanaka M, Yoden A, Abukawa D, Sasahara Y, Kure S. Comprehensive Targeted Sequencing Identifies Monogenic Disorders in Patients with Early-onset Refractory Diarrhea. J Pediatr Gastroenterol Nutr. 2020:71;333-339.

・Uchiyama K, Haruyama Y, Shiraishi H, Katahira K, Abukawa D, Ishige T, Tajiri H, Uchida K, Uchiyama K, Washio M, Kobashi E, Maekawa A, Okamoto K, Sairenchi T, Imamura Y, Ohhira S, Hata A, Kobashi G. Association between Passive Smoking from the Mother and Pediatric Crohn’s Disease: A Japanese Multicenter Study. Int J Environ Res Public Health. 2020:17;2926.

・Wesley T Smith, Kenneth T Shiao, Elena Varotto, Yinmei Zhou, Iijima M, Doralina L Anghelescu, Cheng Cheng, Sima Jeha, Ching-Hon Pui, Sue C Kaste, Inaba H. Evaluation of Chest Radiographs of Children with Newly Diagnosed Acute Lymphoblastic Leukemia. J Pediatr. 2020:223;120-127.

・Yagi H, Sato K, Arakawa N, Inoue T, Nishida Y, Yamada S, Ishige T, Yamada Y, Arakawa H, Takizawa T. Expression of Leucine-rich Repeatcontaining Protein 32 Following Lymphocyte Stimulation in Patients with Non-IgE-mediated Gastrointestinal Food Allergies. Yale J Biol Med. 2020:93;645-655.

・Yagi H, Takizawa T, Sato K, Inoue T, Nishida Y, Yamada S, Ishige T, Hatori R, Inoue T, Yamada Y, Arakawa H. Interleukin 2 receptor-a expression after lymphocyte stimulation for non-IgE-mediated gastrointestinal food allergies. Allergol Int. 2020:69;287-289.

・Zen Y, Kondou H, Nakazawa A, Tanikawa K, Hasegawa Y, Bessho K, Imagawa K, Ishige T, Inui A, Suzuki M, Kasahara M, Yamamoto K, Yoshioka T, Kage M, Hayashi H. Proposal of a liver histologybased scoring system for bile salt export pump deficiency. Hepatol Res. 2020:50;754-762.

2019

・Hagiwara S, Kudo T, Kakuta F, Inoue M, Yokoyama K, Umetsu S, Iwama I, Yodoshi T, Tatsuki M, Shimizu T, Nakayama Y. Clinical Safety and Utility of Pediatric Balloon Assisted Enteroscopy; A Multicenter Prospective Study in Japan. J Pediatr Gastroenterol Nutr. 2019:68;306-310.

・Inoue T, Sato K, Ohashi H, Motojima T, Takizawa T. Interstitial 6q25 microdeletion syndrome: 46, XX, del(6) (q25.2q26). Pediatr Int.2019:61;618-620.

・Ishige T. Growth Failure of Pediatric Onset Inflammatory Bowel Disease – Mechanisms, Epidmiology and Management. Transl Pediatr. 2019:8;16-22.

・Kinoshita D, Hada S, Fujita R, Matsunaga N, Sakaki H, Ohki Y. Maximal sterile barrier precautions independently contribute to decreased central line – associated bloodstream infection in very low birth weight infants: A prospective multicenter observational study. Am J Infect Control. 2019:47;1365-1369.

・Miyakawa Y, Akasawa K, Matsubara Y, Ihara K, Ohtsu Y, Kamasaki H, Kitsuda K, Kobayashi H, Satoh M, Sano S, Dateki S, Mochizuki H, Yokota I, Hasegawa Y, Kashimada K. Language delay and developmental catch-up would be a clinical feature of pseudohypoparathyroidism type 1A during childhood. Endocr J. 2019:66;215-221.

・Seki M,Furukawa N, Koitabashi N, Obokata M, Simon JC, Arakawa H, Kurabayashi M. Periostin-expressing cell-specific transforming growth factor-β inhibition in pulmonary artery prevents pulmonary arterial hypertension. PLoS One. 2019:14:e0220795.

・Shinagawa M, Ishige T, Igarashi Y, Takizawa T, Arakawa H. Pyoderma Gangrenosum of the Finger Associated With Pediatric Ulcerative Colitis. J Pediatr Gastroenterol Nutr. 2019:69;e88.

・Shiohama T, Fujii K, Miyashita T, Takatani T, Ikehara H, Uchikawa H, Motojima T, Uchida T, Shimojo N. MicroRNAs profiling in fibroblasts derived from patients with Gorlin syndrome. J Hum Genet. 2019:64;757-765.

・Sugitate R, Okubo Y, Nariai H, Matsui A. Duration of Pivalate-conjugated Antibiotics and Blood Glucose Levels Among Pediatric Inpatients: Causal Mediation Analyses and Systematic Review. Pediatr Infect Dis J. 2019: 38;1214-1218.

・Takaoka Y, Kondo Y, Matsunaga K, Aoki Y, Hasegawa E, Tokuda R, Fujisawa T, Morikawa A, Doi S. Allergy and Anaphylactic Reaction to Loquat (Eriobotrya Japonica) Are Induced by a Bet v 1 Homolog. J Investig Allergol Clin Immunol. 2019:29;378-398.

・Tanaka T, Yoshioka K, Nishikomori R, Sakai H, Abe J, Yamashita Y, Hiramoto R, Morimoto A, Ishii E, Arakawa H, Kaneko U, Ohshima Y, Okamoto N, Ohara O, Hata J, Shigematsu Y, Kawai T, Yasumi T, Heike T. National survey of Japanese patients with mevalonate kinase deficiency reveals distinctive genetic and clinical characteristics. Mod Rheumatol. 2019:29;181-187.

・Yagi H, Takizawa T, Sato K, , Inoue T, Nishida Y, Ishige T, Tatsuki M, Hatori R, Kobayashi Y, Yamada Y, Arakawa H.Severity Scales of non-IgE-mediated Gastrointestinal Food Allergies in Neonates and Infants. Allergol Int. 2019:68:178-184.

・Yanagi T, Ushijima K, Koga H, Tomomasa T, Tajiri H, Kunisaki R, Ishige T, Yamada H, Arai K, Yoden A, Aomatsu T, Nagata S, Uchida K, Ohtsuka Y, Shimizu T. Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan. Intest Res. 2019:17;476-485.

2018

・Arakawa N, Takizawa T, Nishida Y, Yagi H, Arakawa H. Chronic recurrent ostemyelitis with systemic juvenile idiopathic arthritis. Kitakanto Med J. 2018:68;167-169.

・Ashraf S, Kudo H, Rao J, Kikuchi A, Widmeier E, Lawson JA, Tan W, Hermle T, Warejko JK, Shril S, Airik M, Jobst-Schwan T, Lovric S, Braun DA, Gee HY1, Schapiro D, Majmundar AJ, Sadowski CE, Pabst WL, Daga A, van der Ven AT, Schmidt JM, Low BC, Gupta AB, Tripathi BK, Wong J, Campbell K, Metcalfe K, Schanze D, Niihori T, Kaito H, Nozu K, Tsukaguchi H, Tanaka R, Hamahira K, Kobayashi Y, Takizawa T, Funayama R, Nakayama K, Aoki Y, Kumagai N, Iijima K, Fehrenbach H, Kari JA, El Desoky S, Jalalah S, Bogdanovic R, Stajić N, Zappel H, Rakhmetova A, Wassmer SR, Jungraithmayr T, Strehlau J, Kumar AS, Bagga A, Soliman NA, Mane SM, Kaufman L, Lowy DR, Jairajpuri MA, Lifton RP, Pei Y, Zenker M, Kure S, Hildebrandt F. Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. Nat Commun. 2018:11;e004486.

・Azad GK, Ito K, Sailaja BS, Biran A, Nissim-Rafinia M, Yamada Y, Brown DT, Takizawa T, Meshorer E. PARP1-dependent eviction of the linker histone H1 mediates immediate early gene expression during neuronal activation. J Cell Biol. 2018:217;473-481.

・Hamajima E, Noda M, Nai E, Akiyama S, Ikuta Y, Obana N, Kawaguchi T, Hayashi K, Oba K, Yoshida T, Katori T, Kokaji M. Therapy with propylthiouracil for T3-predominant neonatal Graves’ disease: A case report. Clin Pediatr Endocrinol. 2018:27;165-169.

・Ichinomiya K, Maruyama K, Koizumi A, Inoue F, Fukuda K, Kaburagi K, Miyakawa Y. Neonatal Research Network of Japan. Comparison of neurodevelopmental outcomes between monochorionic and dichorionic twins with birth weight ≤ 1500g in Japan: a register-based cohort study. J Perinatol. 2018:38;1407-1413.

・Inoue Y, Shimizu A, Suto M, Kishi C, Takahashi A, Yasuda M, Iijima M, Arakawa H, Ishikawa O. Cutaneous squamous cell carcinoma, thyroid cancer and Langerhans cell histiocytosis in a patient with X-linked recessive Mendelian susceptibility to mycobacterial diseases with a nuclear factor-KB essential modifier mutation. J Dermatol. 2018:45;1017-1019.

・Ishige T, Igarashi Y, Hatori R, Tatsuki M, Sasahara Y, Takizawa T, Arakawa H. IL-10RA Mutation as a Risk Factor of Severe Influenza-Associated Encephalopathy: A Case Report. Pediatrics. 2018:141;pii:e20173548.

・Ishiyama A, Muramatsu K, Uchino S, Sakai C, Matsushima Y, Makioka N, Ogata T, Suzuki E, Komaki H, Sasaki M, Mimaki M, Goto YI, Nishino I. NDUFAF3 variants that disrupt mitochondrial complex I assembly may associate with cavitating leukoencephalopathy. Clin Genet. 2018:93;1103-1106.

・Ito K, Noguchi A, Uosaki Y, Taga T, Arakawa H, Takizawa T. Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes. Mol Biol Cell. 2018:29;202-219.

・Ito K, Takizawa T. Nuclear Architecture in the Nervous System: Development, Function, and Neurodevelopmental Diseases. Front Genet. 2018:9;308.

・Itoh-Nagato N, Inoue Y, Nagao M, Fujisawa T, Shimojo N, Iwata T, J-OIT grouph. Desensitization to a whole egg by rush oral immunotherapy improves the quality of life of guardians: A multicenter, randomized, parallel-group, delayed-start design study. Allergol Int. 2018:67;209-216.

・Matsuo H, Yoshida K, Fukumura K, Nakatani K, Noguchi Y, Takasaki S, Noura M, Shiozawa Y, Shiraishi Y, Chiba K, Tanaka H, Okada A, Nannya Y, Takeda J, Ueno H, Shiba N, Yamato G, Handa H, Ono Y, Hiramoto N, Ishikawa T, Usuki K, Ishiyama K, Miyawaki S, Itonaga H, Miyazaki Y, Kawamura M, Yamaguchi H, Kiyokawa N, Tomizawa D, Taga T, Tawa A, Hayashi Y, Mano H, Miyano S, Kamikubo Y, Ogawa S, Adachi S. Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia. Blood Adv. 2018:2;2879-2889.

・Miura M, Kobayashi T, Kaneko T, Ayusawa M, Fukazawa R, Fukushima N, Fuse S, Hamaoka K, Hirono K, Kato T, Mitani Y, Sato S, Shimoyama S, Shiono J, Suda K, Suzuki H, Maeda J, Waki K; and The Z-score Project 2nd Stage Study Group, Kato H, Saji T, Yamagishi H, Ozeki A, Tomotsune M, Yoshida M, Akazawa Y, Aso K, Doi S, Fukasawa Y, Furuno K, Hayabuchi Y, Hayashi M, Honda T, Horita N, Ikeda K, Ishii M, Iwashima S, Kamada M, Kaneko M, Katayama H, Kawamura Y, Kitagawa A, Komori A, Kuraishi K, Masuda H, Matsuda S, Matsuzaki S, Mii S, Miyamoto T, Moritou Y, Motoki N, Nagumo K, Nakamura T, Nishihara E, Nomura Y, Ogata S, Ohashi H, Okumura K, Omori D, Sano T, Suganuma E, Takahashi T, Takatsuki S, Takeda A, Terai M, Toyono M, Watanabe K, Watanabe M, Yamamoto M, Yamamura K. Association of Severity of Coronary Artery Aneurysms in Patients With Kawasaki Disease and Risk of Later Coronary Events. JAMA Pediatr. 2018: 172; e180030.

・Motojima T, Fujii K, Ohashi H, Arakawa H. Catathrenia in Pitt-Hopkins syndrome associated with 18q interstitial deletion. Pediatr Int. 2018:60;479-481.

・Nishizawa T, Ohki Y, Urano H Suzuki T, Kuwashima M. Knotted transpyloric tube in an infant, a patient report. Pediatr Int. 2018:60;310-311.

・Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kim L, Johnson, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and chronic increases of circulating follistatin-like protein 1 normalize energy substrate metabolism in pacinginduced heart failure. Circ Heart Fail. 2018:11;e004486.

・Uehara T, Ishige T, Hattori S, Yoshihashi H, Funato M, Yamaguchi Y, Takenouchi T, Kosaki K. Three patients with DeSanto-Shinawi syndrome: Further phenotypic delineation. Am J Med Genet A. 2018:176;1335-1340.

・Wada A, Muramatsu K, Sunaga Y, Mizuno T, Takei M, Ogasawara S, Uchida M, Tsukida K, Tashiro M. Brainstem infarction associated with HHV-6 infection in an infant. Brain Dev. 2018:40; 242-246.

・Yamato G, Shiba N, Yoshida K, Hara Y, Shiraishi Y, Ohki K, Okubo J, Park MJ, Sotomatsu M, Arakawa H, Kiyokawa N, Tomizawa D, Adachi S, Taga T, Horibe K, Miyano S, Ogawa S, Hayashi Y. RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis. Blood. 2018:131;2266-2270.

2017

・Arakawa H, Hamazaki Y, Kohno Y, Ebisawa M, Kondo N, Nishima S, Nishimuta T, Morikawa A. The Japanese Society of Pediatric Allergy and Clinical Immunology. The Japanese Society of Allergology. Japanese guidelines for childhood asthma 2017. Allergol Int. 2017:66;190-204.

・Fukazawa R, Kobayashi T, Mikami M, Saji T, Hamaoka K, Kato H, Suzuki H, Tsuda E, Ayusawa M, Miura M, Ebata R, Kobayashi T, Yashiro M, Ogawa S. Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999─2010 in Japan. Circulation J. 2017:82;239-246.

・Hara Y, Shiba N, Ohki K, Tabuchi K, Yamato G, Park MJ, Tomizawa D, Kinoshita A, Shimada A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, Hayashi Y. Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non-Down syndrome. Genes Chromosomes Cancer. 2017:56;394-404.

・Hatori R, Tomomasa T, Ishige T, Tatsuki M, Arakawa H. Fecal retention in childhood: Evaluation.on ultrasonography. Pediatr Int. 2017:59;462-466.

・Hazama K, Shiihara T, Tsukagoshi H, Hasegawa S, Dowa Y, Watanabe M. A case of mumps-related acute encephalopathy with biphasic seizures and late reduced diffusion. Brain Dev. 2017:39; 808-810.

・Hosoi K, Ohtsuka Y, Fujii T, Kudo T, Matsunaga N, Tomomasa T, Tajiri H, Kunisaki R, Ishige T, Yamada H, Arai K, Yoden A, Ushijima K, Aomatsu T, Nagata S, Uchida K, Takeuchi K, Shimizu T. Treatment with infliximab for pediatric Crohn’s disease: Nationwide survey of Japan. J Gastroenterol Hepatol. 2017:32;114-119.

・Ichinomiya K, Maruyama K, Inoue T, Koizumi A, Inoue F, Fukuda K, Yamazaki Y, Arakawa H. Perinatal Factors Affecting Serum Hepcidin Levels in Low-Birth-Weight Infants. Neonatology. 2017: 112;180-186.

・Ikeda K, Takizawa T, Naito S, Nakamura K, Sasaki T, Kumagai K, Kobayashi T, Arakawa H. Safety and Efficacy of Catheter Ablation for Pediatric Ventricular Tachyarrhythmia. Kitakanto Med J. 2017:67;287-290.

・Ishige T, Tomomasa T, Hatori R, Tatsuki M, Igarashi Y, Sekine K, Arakawa H. Temporal Trend of Pediatric Inflammatory Bowel Disease: Analysis of National Registry Data 2004 to 2013 in Japan. J Pediatr Gastroenterol Nutr. 2017:65;e80-e82.

・Ishii Y, Miyamoto T, Nakajima K,Tanaka K,Ikeda K,Seki M, Shimoyama S, Kobayashi T, Arakawa H. Usefulness of Percutaneous Transluminal Pulmonary Artery Balloon Angioplasty after Bilateral Pulmonary Artery Banding: Prevention against Additional Surgical Interventions. Interv Cardiol J. 2017:3;1-7.

・Kamata A, Muramatsu K, Sawaura N, Makioka N, Ogata T, Kuwashima M, Arakawa H. Demyelinating neuropathy in a 6-year-old girl with autism spectrum disorder. Pediatr Int. 2017:59;951-954.

・Kawashima J, Okuno H, Shiba N, Yoshida K, Shiraishi Y, Hara Y, Yamato G, Iijima M, Kaburagi T, Kanazawa T, Ohki K, Horibe K, Miyano S, Ogawa S, Hayashi Y, Arakawa H. Whole-Exome Sequencing in a Pediatric Patient with Relapsed/Refractory Burkitt Leukemia Resistant to Conventional Chemotherapy. Arch Paediatr Dev Pathol. 2017:1;1001.

・Kobayashi Y. Aizawa A, Takizawa T, Igarashi K, Hatada I and Arakawa H. Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome. BMC Research Notes. 2017:10;480-492.

・Lardelli RM, Schaffer AE, Eggens VRC, Zaki MS, Grainger S, Sathe S, Nostrand ELV, Schlachetzki Z, Rosti B, Akizu N, Scott E, Heckman LD, Rosti RO, Dikoglu E, Gregor A, G-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, Markmiller S, M-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, çağlayan AO, Bilguvar K, Per H, Fagerberg C, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi N, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Bennett EJ, Yeo GW, Baas F, L-Andersen J, Gleeson JG. Biallelic Mutations in the 3’ Exonuclease TOE1 Cause Pontocerebellar Hypoplasia and Uncover a Role in snRNA Processing. Nat Genet. 2017:49;457-464.

・Maruyama K. Serum a-fetoprotein concentration in extremely low-birthweight infants. Pediatr Int. 2017:59;159-162.

・Muramatsu K, Sawaura N, Ogata T, Makioka N, Tomita K, Motojima T, Ida K, Hazama K, Arakawa H. Efficacy and tolerability of levetiracetam for pediatric refractory epilepsy. Brain Dev. 2017:39; 231-235.

・Oyanagi T, Takizawa T, Aizawa A,Solongo O, Yagi H, Nishida Y, Koyama H, Saitoh A, Arakawa H. Suppression of MUC5AC expression in human bronchial epithelial cells by interferon-y. Allergol Int. 2017:66;75-82.

・Suzuki T, Sasahara Y, Kikuchi A, Kakuta H, Kashiwabara T, Ishige T, Nakayama Y, Tanaka M, Hoshino A, Kanegane H, Abukawa D, Kure S. Targeted Sequencing and mmunological Analysis Reveal the Involvement of Primary Immunodeficiency Genes in Pediatric IBD: a Japanese Multicenter Study. J Clin Immunol. 2017:37;67-79.

・Yamato G, Shiba N, Yoshida K, Shiraishi Y, Hara Y, Ohki K, Okubo J, Okuno H, Chiba K, Tanaka H, Kinoshita A, Moritake H, Kiyokawa N, Tomizawa D, Park MJ, Sotomatsu M, Taga T, Adachi S, Tawa A, Horibe K, Arakawa H, Miyano S, Ogawa S, Hayashi Y. ASXL2 mutations are frequently found in pediatric AML patients with t(8; 21)/RUNX1-RUNX1T1 and associated with a better prognosis. GenesChromosomes Cancer. 2017:56;382-393.

・Yamato G, Yamaguchi H, Handa H, Shiba N, Kawamura M, Wakita S, Inokuchi K, Hara Y, Ohki K, Okubo J, Park MJ, Sotomatsu M, Arakawa H, Hayashi Y. Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia. Genes Chromosomes Cancer. 2017:56;800-809.

・Yoshimura A, Yuan J. -H., Hashiguchi A, Hiramatsu Y, Ando M, Higuchi Y, Nakamura T, Okamoto Y, Matsumura K, Hamano T, Sawaura N, Shimatani Y, Kumada S, Okumura Y, Miyahara J, Yamaguchi Y, Kitamura S, Haginoya K, Mitsui J, Ishiura H, Tsuji S, Takashima H. Clinical and mutational spectrum of Japanese patients with Charcot-Marie-Tooth disease caused by GDAP1 variants. Clin Genet. 2017:92;274-280.

2016

・Hatori R, Tomomasa T, Ishige T, Tatsuki M, Arakawa H. Evaluation of fecal retention via ultrasonography in childhood. Pediatr Int. 2016:59;4

・Ito K, Sanosaka T, Igarashi K, Ideta-Otsuka M, Aizawa A, Uosaki Y, Noguchi A, Arakawa H, Nakashima K, Takizawa T. Identification of genes associated with the astrocyte-specific gene Gfap during astro- cyte differentiation. Sci Rep. 2016:4;23903.

・Kobayashi T, Kobayashi T, Fuse S, Sakamoto N, Mikami M, Ogawa S, Hamaoka K, Arakaki Y, Nakamura T, Nagasawa H, Kato T, Jibiki T, Iwashima S, Yamakawa M, Ohkubo T, Shimoyama S, Aso K, Sato S, Saji T. Z Score Project Investigators. A New Z Score Curve of the Coronary Arterial Internal Diameter Using the Lambda-Mu-Sigma Method in a Pediatric Population. J Am Soc Echocardiogr. 2016:29;794-801.

・Li L, Ohtsu Y, Nakagawa Y, Masuda K, Kojima I. Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms. Endocr J. 2016: 63;715-725.

・Narumi S, Amano N, Ishii T, Katsumata N, Muroya K, Adachi M, Toyoshima K, Tanaka Y, Fukuzawa R, Miyako K, Kinjo S, Ohga S, Ihara K, Inoue H, Kinjo T, Hara T, Kohno M, Yamada S, Urano H, Kitagawa Y, Tsugawa K, Higa A, Miyawaki M, Okutani T, Kizaki Z, Hamada H, Kihara M, Shiga K, Yamaguchi T, Kenmochi M, Kitajima H, Fukami M, Shimizu A, Kudoh J, Shibata S, Okano H, Miyake N, Matsumoto N, Hasegawa T. SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7. Nat Genet. 2016:48;792-797.

・Onouchi Y, Fukazawa R, Yamamura K, Suzuki H, Kakimoto N, Suenaga T, Takeuchi T, Hamada H, Honda T, Yasukawa K, Terai M, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Yoshiyama M, Miyashita R, Murata Y, Fujino A, Ozaki K, Kawasaki T, Abe J, Seki M, Kobayashi T, Arakawa H, Ogawa S, Hara T, Hata A, Tanaka T. Variations in ORAI1 Gene Associated with Kawasaki Disease. PLoS One. 2016:11;e0145486.

・Saleem MA, Kobayashi Y. Cell biology and genetics of minimal change disease. F1000Res. 2016: 30; 5: F1000 Faculty Rev-412.

・Seki M, Kuwata S, Kurishima C, Nakagawa R, Inuzuka R, Sugimoto M, Saiki H, Iwamoto Y, Ishido H, Masutani S, Senzaki H. Mechanism of aortic root dilation and cardiovascular function in tetralogy of Fallot. Pediatr Int. 2016:58;323-330.

・Seki M, LaCanna R, Powers JC, Vrakas C, Liu F, Berretta R, Chacko G, Holten J, Jadiya P, Wang T, Arkles JS, Copper JM, Houser SR, Huang J, Patel VV, Recchia FA. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation. J Pharmacol Exp Ther. 2016:358;441-449.

・Shiba N, Ohki K, Kobayashi T, Hara Y, Yamato G, Tanoshima R, Ichikawa H, Tomizawa D, Park MJ, Shimada A, Sotomatsu M, Arakawa H, Horibe K, Adachi S, Taga T, Tawa A, Hayashi Y. High PRDM16 expression identifies a prognostic subgroup of pediatric acute myeloid leukemia correlated to FLT3-ITD, MLL-PTD, and NUP98-NSD1. Br J Haematol. 2016:172;581-591.

・Shiba N, Yoshida K, Shiraishi Y, Okuno Y, Yamato G, Hara Y, Nagata Y, Chiba K, Tanaka H, Terui K, Kato M, Park MJ, Ohki K, Shimada A, Takita J, Tomizawa D, Kudo K, Arakawa H, Adachi S, Taga T, Tawa A, Ito E, Horibe K, Sanada M, Miyano S, Ogawa S, Hayashi Y. Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia. Br J Haematol. 2016:175;476-489.

・Sugimoto M, Saiki H, Tamai A, Seki M, Inuzuka R, Masutani S, Senzaki H. Ventricular fibrogenesis activity assessed by serum levels of procollagen 7type III N-terminal amino peptide during the staged Fontan procedure. J Thorac Cardiovasc Surg. 2016:151;1518-1526.

・Suzuki T, Miyake N, Tsurusaki Y, Okamoto N, Alkindy A, Inaba A, Sato M, Ito S, Muramatsu K, Kimura S, Ieda D, Saitoh S, Hiyane M, Suzumura H, Yagyu K, Shiraishi H, Nakajima M, Fueki N, Habata Y, Ueda Y, Komatsu Y, Yan K, Shimoda K, Shitara Y, Mizuno S, Ichinomiya K, Sameshima K, Tsuyusaki Y, Kurosawa K, Sakai Y, Haginoya K, Kobayashi Y, Yoshizawa C, Hisano M, Nakashima M, Saitsu H, Takeda S, Matsumoto N. Molecular genetic analysis of 30 families with Joubert syndrome. Clin Genet.2016:90;526-535. doi: 10.1111/cge.12836.

・Takagi M, Takahashi M, Ohtsu Y, Sato T, Narumi S, Arakawa H, Hasegawa T. A novel mutation in HESX1 causes combined pituitary hormone deficiency without septo optic dysplasia phenotypes. Endocr J. 2016:63;405-410.

・Takahashi Y, Sano R, Kominato Y, Kubo R, Takahashi K, Nakajima T, Takeshita H, Ishige T. A case of sudden unexpected infant death involving a homozygotic twin with the thermolabile CPT2 variant, accompanied by rotavirus infection and treatment with an antibiotic containing pivalic acid. Leg Med. 2016:22;13-19.

・Yoshizawa C, Kobayashi Y, Ikeuchi Y, Tashiro M, Kakegawa S, Watanabe T, Goto Y, Nakanishi K, Yoshikawa N, Arakawa H. Congenital nephrotic syndrome with a novel NPHS1 mutation. Pediatr Int. 2016:58;1211-1242.

2015

・Akatsuka J, Mochizuki M, Musha I, Ohtake A, Kobayashi K, Kikuchi T, Kikuchi N, Kawamura T, Urakami T, Sugihara S, Hoshino T, Amemiya S. Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes. The ratio of glycated albumin to hemoglobin A1c measured in IFCC units accurately represents the glycation gap. Endocr J. 2015:62;161-172.

・Hagiwara S, Nakayama Y, Tagawa M, Arai K, Ishige T, Murakoshi T, Sekine H, Abukawa D,Yamada H, Inoue M, Saito T, Kudo T, Seki Y. Pediatric Patient and Parental Anxiety and Impressions Related to Initial Gastrointestinal Endoscopy: A Japanese Multicenter Questionnaire Study. Scientifica. 2015: doi:10.1155/2015/797564.

・Hamano K, Nakagawa Y, Ohtsu Y, Li L, Medina J, Tanaka Y, Masuda K, Komatsu M, Kojima I. Lactisole inhibits the glucose-sensing receptor T1R3 expressed in mouse pancreatic β-cells. J Endocrinol. 2015:226;57-66.

・Ishige T, Yagi H, Tatsuki M, Hatori R, Nishida Y, Takizawa T, Arakawa H. Endoscopic findings in the acute phase of food protein-induced enterocolitis syndromae. Pediatr Allergy Immunol. 2015: 26;90-92.

・Jo A, Mitani S, Shiba N, Hayashi Y, Hara Y, Takahashi H, Tsukimoto I, Tawa A, Horibe K, Tomizawa D, Taga T, Adachi S, Yoshida T, Ichikawa H. High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML. Leukemia. 2015:29;1076-1083.

・Kato M, Suzuki K, Yamada Y, Maruyama K, Hayashi Y, Mochizuki H, Virus detection and cytokine profile in relation to age among acute exacerbations of childhood asthma. Allergol. Int. 2015: 67;64-70.

・Kobayashi Y, Saleem MA. Hemopexin in Minimal Change Nephrotic Syndrome. In Kaneko K editor. Molecular mechanisms in the pathogenesis of idiopathic nephrotic syndrome. Springer Japan. 2015:13-23.

・Kojima I, Nakagawa Y, Ohtsu Y, Hamano K, Medina J, Nagasawa M. Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cells. J Diabetes Investig. 2015:6;256-263.

・Sano H, Ohki K, Park MJ, Shiba N, Hara Y, Sotomatsu M, Tomizawa D, Taga T, Kiyokawa N, Tawa A, Horibe K, Adachi S, Hayashi Y. CSF3R and CALR mutations in paediatric myeloid disorders and the association of CSF3R mutations with translocations, including t(8; 21). Br J Haematol. 2015:170;391-397.

・Tajiri H, Nishi J, Ushijima K, Shimizu T, Ishige T, Shimizu M, Tanaka H, Brooks S. A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection. Int J Antimicrob Agents. 2015:46;586-589.

2014

・Hagiwara S, Mochizuki H, Muramatsu R, Koyama H, Yagi H, Nishida Y, Kobayashi T, Sakamoto N, Takizawa T, Arakawa H. Reference values for Japanese children’s respiratory resistance using the LMS method. Allergol Int. 2014:63;113-119.

・Ichinomiya K, Ichinomiya K, Inoue F, Koizumi A, Inoue T, Fujiu T, Maruyama K. Problems with using total serum bilirubin as a criterion for phototherapy in extremely low-birthweight infants. Pediatr Int. 2014:56;731-734.

・Inamura N, Kubota A, Ishii R, Ishii Y, Kawazu Y, Hamamichi Y, Yoneda A, Kawahara H, Okuyama H, Kayatani F. Efficacy of the circulatory management of an antenatally diagnosed congenital diaphragmatic hernia: outcomes of the proposed strategy. Pediatr Surg Int. 2014:30;889-894.

・Ishii Y, Inamura N, Kayatani F, Iwai S, Kawata H, Arakawa H, Kishimoto H. Evaluation of bilateral pulmonary artery banding for initial palliation in single-ventricle neonates and infants: risk factors for mortality before the bidirectional Glenn procedure. Interact Cardiovasc Thorac Surg. 2014:19;807-811.

・Kojima I, Nakagawa Y, Ohtsu Y, Medina A, Nagasawa M. Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists. Endocrinol Metab(Seoul). 2014:29;12-19.

・Matsuo H, Kajihara M, Tomizawa D, Watanabe T, Saito AM, Fujimoto J, Horibe K, Kodama K,Tokumasu M, Itoh H, Nakayama H, Kinoshita A, Taga T, Tawa A, Taki T, Shiba N, Ohki K, Hayashi Y, Yamashita Y, Shimada A, Tanaka S, Adachi S. EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia. Haematologica. 2014:99;225-227.

・Miyamoto T, Ikeda K, Ishii Y, Kobayashi T. Rupture of a coronary artery aneurysm in Kawasaki disease: a rare case and review of the literature for the past 15 years. J Thorac Cardiovasc Surg. 2014:147;67-69.

・Nakagawa Y, Ohtsu Y, Nagasawa M, Shibata H, Kojima I. Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3. Endocr J. 2014: 61; 119─131.

・Ohtsu Y, Nakagawa Y, Nagasawa M, Takeda S, Arakawa H, Kojima I. Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells. Mol Cell Endocrinol. 2014: 394;70-79.

・Shiba N, Funato M, Ohki K, Park MJ, Mizushima Y, Adachi S, Kobayashi M, Kinoshita A, Sotomatsu M, Arakawa H, Tawa A, Horibe K, Tsukimoto I, Hayashi Y. Mutations of the GATA2 and CEBPA genes in paediatric acute myeloid leukaemia. Br J Haematol. 2014:164;142-145.

・Shiba N, Ohki K, Park MJ, Sotomatsu M, Kudo K, Ito E, Sako M, Arakawa H, Hayashi Y. SETBP1 mutations in juvenile myelomonocytic leukaemia and myelodysplastic syndrome but not in paediatric acute myeloid leukaemia. Br J Haematol. 2014:164;156-159.

・Takahashi Y, Sano R, Nakajima T, Kominato Y, Kubo R, Takahashi K, Ohshima N, Hirano T, Kobayashi S, Shimada T, Tokue H, Awata S, Hirasawa S, Ishige T. Combination of postmortem mass spectrometry imaging and genetic analysis reveals very long-chain acyl-CoA dehydrogenase deficiency in a case of infant death with liver steatosis. Forensic Sci Int. 2014:244;e34-e37.

・Yi SH, He XB, Rhee YH, Park CH, Takizawa T, Nakashima K, Lee S. HFoxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation. Development. 2014:141;761-772.

・Yoshii T, Miyamoto T, Inui A, Tanaka Y, Yoshitake S, Seki M, Kobayashi T. Fontan completion following flow adjustable bilateral pulmonary artery banding. Int Heart J. 2014:13;552-554.

2013

・Inuzuka R, Seki M, Sugimoto M, Saiki H, Masutani S, Senzaki H. Pulmonary arterial wall stiffness and its impact on right ventricular afterload in patients with repaired tetralogy of fallot. Ann Thorac Surg. 2013:96;1435-1441.

・Ishii Y, Inamura N, Kawazu Y, Kayatani F, Arakawa H. ‘I-shaped’ sign in the upper mediastinum: a novel potential marker for antenatal diagnosis of d-transposition of the great arteries. Ultrasound Obstet Gynecol. 2013:41;667-671.

・Kobayashi T, Kobayashi T, Morikawa A, Ikeda K, Seki M, Shimoyama S, Ishii Y, Suzuki T, Nakajima K, Sakamoto N, Arakawa H. Efficacy of Intravenous Immunoglobulin Combined with Prednisolone Following Resistance to Initial Intravenous Immunoglobulin Treatment of Acute Kawasaki Disease. J Pediatr. 2013:163;521-526.

・Ohki Y, Maruyama K, Harigaya A, Kohno M, Arakawa H. Complications of peripherally inserted central venous catheter in Japanese neonatal intensive care units. Pediatr Int. 2013:55;185-189.

・Saitsu H, Nishimura T , Muramatsu K(3名共筆頭著者), Kodera H, Kumada S, Sugai K, Kasai-Yoshida E, Sawaura N, Nishida H, Hoshino A, Ryujin F, Yoshioka S, Nishiyama K, Kondo Y, Tsurusaki Y, Nakashima M, Miyake N, Arakawa H, Kato M, Mizushima N, Matsumoto N. De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nat Genet. 2013:45;445-449.

・Shiba N, Ichikawa H, Taki T, Park MJ, Jo A, Mitani S, Kobayashi T, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y. NUP98-NSD1 gene fusion and its related gene expression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia. Genes Chromosomes Cancer. 2013:52;683-693.

・Shiraishi Y, Sato Y, Chiba K, Okuno Y, Nagata Y, Yoshida K, Shiba N, Hayashi Y, Kume H, Homma Y, Sanada M, Ogawa S, Miyano S. An empirical Bayesian ework for somatic mutation detection from cancer genome sequencing data. Nucleic Acids Res. 2013:41;e89.

・Tsurusaki Y, Kobayashi Y, Hisano M, Ito S, Doi H, Nakashima M, Saitsu H, Matsumoto N, Miyake N. The diagnostic utility of exome sequencing in Joubert syndrome and related disorders. J Hum Genet. 2013:58;113-115.

・Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Sanada M, Park MJ, Terui K, Suzuki H, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S. The landscape of somatic mutations in Down syndrome-related myeloid disorders. Nat Genet. 2013:45;1293-1299.

・Yoshimi A, Kamachi Y, Imai K, Watanabe N, Nakadate H, Kanazawa T, Ozono S, Kobayashi R, Yoshida M, Kobayashi C, Hama A, Muramatsu H, Sasahara Y, Jakob M, Morio T, Ehl S, Manabe A, Niemeyer C, Kojima S. Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia. Pediatr Blood Cancer. 2013:60;836-841.

・Yoshimoto A, Miyamoto T, Ozaki S, Kobayashi T, Kobayashi T. Flow-adjustable bilateral pulmonary artery banding in the neonatal period for severe congenital heart diseases. Gen Thorac Cardiovasc Surg. 2013:61;340-344.

2012

・Arakawa H, Yagi H, Koyama H, Nakajima N, Takizawa T. Characteristics and natural course of neonatal and infantile gastrointestinal milk allergy and the efficacy of oral immunotherapy. Clin Exp Allergy. 2012: 12; 20-24.

・Doisaki S, Muramatsu H, Shimada A, Takahashi Y, Mori-Ezaki M, Sato M, Kawaguchi H, Kinoshita A, Sotomatsu M, Hayashi Y, Furukawa-Hibi Y, Yamada K, Hoshino H, Kiyoi H, Yoshida N, Sakaguchi H, Narita A, Wang X, Ismael O, Xu Y, Nishio N, Tanaka M, Hama A, Koike K, Kojima S. Somatic mosa- icism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia. Blood. 2012: 120; 1485- 1488.

・Hashimoto Y, Muramatsu K(2名共筆頭著者), Kunii M, Yoshimura S, Yamada M, Sato T, Ishida Y, Harada R, Harada A. Uncovering genes required for neuronal morphology by morphology-based gene trap screening with a revertible retrovirus vector. FASEB J. 2012: 26; 4662-4674.

・Ishii Y, Inamura N, Kayatani F. Congenital aneurysm of the right atrial appendage in a fetus. Pediatr Cardiol. 2012: 33; 1227-1229.

・Kato M, Ishioka T, Kita H, Kozawa K, Hayashi Y, Kimura H. Eosinophil granular proteins damage bronchial epithelial cells infected with respiratory syncytial virus. Int Arch Allergy Immunol. 2012: 158 Suppl 1; 11-18.

・Kawasaki H, Seki M, Saiki H, Masutani S, Senzaki H. Noninvasive assessment of left ventricular contractility in pediatric patients using the maximum rate of pressure rise in peripheral arteries. Heart Vessels. 2012: 27; 384-90.

・Kobayashi T, Saji T, Otani T, Takeuchi K, Nakamura T, Arakawa H, Kato T, Hara T, Hamaoka K, Ogawa S, Miura M, Nomura Y, Fuse S, Ichida F, Seki M, Fukazawa R, Ogawa C, Furuno K, Tokunaga H, Takatsuki S, Hara S, Morikawa A. On behalf of the RAISE study group investigators. Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial. Lancet. 2012: 379; 1613-1620.

・Kobayashi Y, Aizawa A, Takizawa T, Yoshizawa C, Horiguchi H, Ikeuchi Y, Kakegawa S, Watanabe T, Maruyama K, Morikawa A, Hatada I, Arakawa H. DNA methylation changes between relapse and remission of minimal change nephrotic syndrome. Pediatr Nephrol. 2012: 27; 2233-2241.

・Maruyama K, Fujiu T. Effects of prophylactic indomethacin on renal and intestinal blood flow in premature infants. Pediatr Int. 2012: 54; 480-485.

・Mizuno T, Sakai H, Nishikomori R, Oshima K, Ohara O, Hata I, Shigematsu Y, Ishige T, Tamura K, Arakawa H. Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome. Rheumatol Int. 2012: 32; 3761-3614.

・N G Papadopoulos, H Arakawa, K-H Carlsen, A Custovic, J Gern, R Lemanske, P Le Souef, M Mäkelä, G Roberts, G Wong, H Zar, C A Akdis, L B Bacharier, E Baraldi, H P van Bever, J de Blic, A Boner, W Burks, T B Casale, J A Castro-Rodriguez, Y Z Chen, Y M El-Gamal, M L Everard, T Frischer, M Geller, J Gereda, D Y Goh, T W Guilbert, G Hedlin, P W Heymann, S J Hong, E M Hossny, J L Huang, D J Jackson, J C de Jongste, O Kalayci, N Aït-Khaled, S Kling, P Kuna, S Lau, D K Ledford, S I Lee, A H Liu, R F Lockey, K Lødrup-Carlsen, J Lötvall, A Morikawa, A Nieto, H Paramesh, R Pawankar, P Pohunek, J Pongracic, D Price, C Robertson, N Rosario, L J Rossenwasser, P D Sly, R Stein, S Stick, S Szefler, L M Taussig, E Valovirta, P Vichyanond, D Wallace, E Weinberg, G Wennergren, J Wildhaber, R S Zeiger. International consensus on (ICON) pediatric asthma. Allergy. 2012: 67; 976-997.

・Nakamura K, Kato M, Sasaki A, Shiihara T, Hayasaka K. Respiratory syncytial virus-associated encephalopathy complicated by congenital myopathy. Pediatr Int. 2012: 54; 709-711.

・Onouchi Y, Ozaki K, Burns JC, Shimizu C, Terai M, Hamada H, Honda T, Suzuki H, Suenaga T, Takeuchi T, Yoshikawa N, Suzuki Y, Yasukawa K, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Iwahashi S, Miyashita R, Murata Y, Sasago K, Takahashi A, Kamatani N, Kubo M, Tsunoda T, Hata A, Nakamura Y, Tanaka T. Japan Kawasaki Disease Genome Consortium; US Kawasaki Disease Genetics Consortium. A genome-wide association study identifies three new risk loci for Kawasaki disease. Nat Genet. 2012: 44; 517-521.

・Saiki H, Kojima T, Seki M, Matsutani S, Senzaki H. Marked disparity in mechanical wall properties between ascending and descending aorta in patients with tetralogy of Fallot. Eur J Cardiothorac Surg. 2012: 41; 570-573.

・Sailaja BS, Takizawa T, Meshorer E. Chromatin immunoprecipitation in mouse hippocampal cells and tissues. Methods Mol Biol. 2012: 809; 353-364.

・Sano H, Shimada A, Taki T, Murata C, Park MJ, Sotomatsu M, Tabuchi K, Tawa A, Kobayashi R, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y. RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse: a study of the Japanese Childhood AML Cooperative Study Group. Int J Hematol. 2012: 95; 509-515.

・Seki M, Kurishima C, Kawasaki H, Masutani S, Senzaki H. Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal aortic mechanical property. Eur J Cardiothorac Surg. 2012: 41; 277-822.

・Seki M, Kurishima C, Kawasaki H, Matsutani S, Senzaki H. Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal aortic mechanical property. Eur J Cardiothorac Surg. 2012: 41; 277-282.

・Sekine K, Mochizuki H, Inoue Y, Kobayashi T, Suganuma E, Matsuda S, Arakawa H. Regulation of oxidative stress in patients with Kawasaki disease. Inflammation. 2012: 35; 952-958.

・Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y. CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML). Blood. 2012: 119; 2612-2614.

・Shiba N, Park MJ, Taki T, Takita J, Hiwatari M, Kanazawa T, Sotomatsu M, Ishii E, Arakawa H, Ogawa S, Hayashi Y. CBL mutations in infant acute lymphoblastic leukaemia. Br J Haematol. 2012: 156; 672- 674.

・Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y. DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia. Br J Haematol. 2012: 156; 413-414.

・Shiihara T, Miyake T, Izumi S, Watanabe M, Kamayachi K, Kodama K, Nabetani M, Ikemiyagi M, Yamaguchi Y, Sawaura N. Serum and cerebrospinal fluid S100B, neuron-specific enolase , and total tau protein in acute encephalopathy with biphasic seizures and late reduced diffusion. Pediatr Int. 2012: 54; 52-55.

・Shimoyama S, Kobayashi T, Ikeda K, Seki M, Mochizuki H, Hamajima A, Hatakeyama S, Kobayashi T, Arakawa H. Evaluation of the effects of surgical correction of left mediastinal displacement in children with pectus excavatum on pulmonary perfusion, using minimal radiation exposure. Eur Res J. 2012: 40 suppl 56; 5S.

・Sugimoto M, Ishido H, Seki M, Matsutani S, Tamai A, Senzaki H. Findings in the pulmonary vascular bed in the remote phase after Kawasaki disease. Am J Cardiol. 2012: 109; 1219-1222.

・Takami S, Mizuno T, Oyanagi T, Tadaki H, Suzuki T, Muramatsu K, Takizawa T, Arakawa H. Glucocorticoids inhibit MUC5AC production induced by transforming growth factor-a in human respiratory cells. Allergol Int. 2012: 61; 451-459.

・Takanashi J, Takahashi Y, Imamura A, Kodama K, Watanabe A, Tominaga K, Muramatsu K, Barkovich A. Late delirious behavior with 2009 H1N1 Influenza; mild autoimmune-mediated encephalitis. Pediatrics. 2012: 129; e1068-1071.

・Takezaki S, Yamada M, Kato M, Park M, Maruyama K, Yamazaki Y, Chida N, Ohara O, Kobayashi I, Ariga T. Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. J Immunol. 2012: 189; 1521-1526.

・Tamai A, Kurishima C, Seki M, Masutani S, Taketazu M, Senzaki H. Stent Implantation for Effective Treatment of Refractory Chylothorax due to Superior Vena Cava Obstruction as a Complication of Congenital Cardiac Surgery. Clin Med Insights Cardiol. 2012: 6; 97-101.

・Yamada Y, Kato M, Toki F, Watanabe M, Nishi A, Matsushita I, Hirato J, Hayashi Y. Eosinophilic gastrointestinal disorder in an infant with feeding dysfunction. Int Arch Allergy Immunol. 2012: 158 Suppl 1; 83-86.

2011

・Ishii Y, Miyamoto T, Kobayashi T, Kobayashi T. Isolated unilateral agenesis of the pulmonary artery: surgical repair with an artificial graft. Pediatr Cardiol. 2011: 32; 509-511.

・Ishioka T, Kimura H, Kita H, Obuchi M, Hoshino H, Noda M, Nishina A, Kozawa K, Kato M. Effects of respiratory syncytial virus infection and major basic protein derived from eosinophils in pulmonary alveolar epithelial cells(A549). Cell Biol Int. 2011: 35; 467-474.

・Kanai T, Ishiwata T, Kobayashi T, Sato H, Takizawa M, Kawamura Y, Tsujimoto H, Nakatani K, Ishibashi N, Nishiyama M, Hatai Y, Asao Y, Kobayashi T, Takeshita S, Nonoyama S. Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease. Circulation. 2011: 124; 2822-2828.

・Kanazawa T, Shiba N, Aizawa A, Okuno H, Tamura K, Tsukada S, Kumamoto T, Yamada S, Kobayashi Y, Arakawa H. Nelarabine Resistance of Childhood T-Cell Lymphoblastic Leukemia/Lymphoma Cells. Kitakanto Med J. 2011: 61; 119-126.

・Kato M, Tsukagoshi H, Yoshizumi M, Saitoh M, Kozawa K, Yamada Y, Maruyama K, Hayashi Y, Kimura H. Different cytokine profile and eosinophil activation are involved in rhinovirus-and RS virus-induced acute exacerbation of childhood wheezing. Pediatr Allergy Immunol. 2011: 22; e87-94.

・Kato M, Yamada Y, Maruyama K, Hayashi Y. Differential effects of corticosteroids on serum eosinophil cationic protein and cytokine production in rhinovirus- and RS virus-induced acute exacerbation of childhood asthma. Int Arch Allergy Immunol. 2011: 155 Suppl 1; 77-84.

・Nakajima N, Mochizuki H, Muramatsu R, Hagiwara S, Mizuno T, Arakawa H. Relationship between exhaled nitric oxide and small airway lung function in normal and asthmatic children. Allergol Int. 2011: 60: 53-59.

・Nshimuta T, Kondo N, Hmasaki Y, Morikawa A, Nishima S. Japanese guideline for childhood asthma. Allergol Int. 2011: 60; 147-169.

・Oki K, Takita J, Hiwatari M, Nishimura R, Sanada M, Okubo J, Adachi M, Sotomatsu M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S. IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies. Leukemia. 2011:25; 382-384.

・Seki M, Kobayashi T, Kobayashi T, Morikawa A, Otani T, Takeuchi K, Ayusawa M, Tsuchiya K, Yasuda K, Suzuki T, Shimoyama S, Ikeda K, Ishii Y, Arakawa H. External validation of a risk score to predict intravenous immunoglobulin resistance in patients with kawasaki disease. Pediatr Infect Dis J. 2011: 30; 145-147.

・Shiba N, Taki T, Park MJ, Nagasawa M, Kanazawa T, Takita J, Ohnishi H, Sotomatsu M, Arakawa H, Hayashi Y. CBL mutation in childhood therapy-related leukemia. Leukemia. 2011:25; 1356-1358.

・Tatsuki M, Miyazawa R, Tomomasa T, Ishige T, Nakazawa T, Arakawa H. Serum magnesium concentration in children with functional constipation treated with magnesium oxide. World J Gastroenterol. 2011:17; 779-783.

・Tomomasa T, Tajiri H, Kagimoto S, Shimizu T, Yoden A, Ushijima K, Uchida K, Kaneko H, Abukawa D, Konno M, Maisawa S, Kohsaka T, Kobayashi A. Japanese Study Group for Pediatric Ulcerative Colitis.Leukocytapheresis in pediatric patients with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2011: 53; 34-39.

・Yamada Y, Nishi A, Ebara Y, Kato M, Yamamoto H, Morita H, Nomura I, Matsumoto K, Hirato J, Hatakeyama SI, Suzuki N, Hayashi Y. Eosinophilic gastrointestinal disorders in infants: a Japanese case series. Int Arch Allergy Immunol. 2011:155 Suppl 1; 40-45.

2010

・Fuse S, Kobayashi T, Arakaki Y, Ogawa S, Katoh H, Sakamoto N, Hamaoka K, Saji T. Standard method for ultrasound imaging of coronary artery in children. Pediatr Int. 2010: 2; 876-882.

・Ishige T, Tomomasa T, Takebayashi T, Asakura K, Watanabe M, Suzuki T, Miyazawa R, Arakawa H. Inflammatory Bowel Disease in Children: Epidemiological Analysis of the Nationwide IBD Registry in Japan. J Gastroenterol. 2010: 45; 911-917.

・Ishii Y, Suzuki T, Kobayashi T, Arakawa H. Single coronary artery with right ventricular fistula: Case report and literature review. Congenit Heart Dis. 2010: 5; 56-59.

・Kobayashi T, Miyamoto T, Kobayashi T, Ikeda K, Koizuka K, Okamoto H, Miyaji K. Staged repair of truncus arteriosus with interrupted aortic arch: adjustable pulmonary artery banding. Ann Thorac Surg. 2010: 89; 973-975.

・Kondo N, Nishimuta T, Nishima S, Morikawa A, Aihara Y, Akasaka T, Akasawa A, Adachi Y, Arakawa H, Ikarashi T, Ikebe T, Inoue T, Iwata T, Urisu A, Ebisawa M, Ohya Y, Okada K, Odajima H, Katsunuma T, Kameda M, Kurihara K, Kohno Y, Sakamoto T, Shimojo N, Suehiro Y, Tokuyama K, Nambu M, Hamasaki Y, Fujisawa T, Matsui T, Matsubara T, Mayumi M, Mukoyama T, Mochizuki H, Yamaguchi K, Yoshihara S. Japanese Society of Pediatric Allergy and Clinical Immunology. Japanese pediatric guidelines for the treatment and management of bronchial asthma 2008. Pediatr Int. 2010: 52; 319-326.

・Morikawa A. Use of Theophylline and Sodium Cromoglycate in Pediatric Asthma. Allergy Frontiers: Therapy and Prevention. 2010: 5: 727-735.

・Nagai Y, Mizuno T, Yoshizawa C, Ishikawa O. Fatal interstitital pneumonia in juvenile dermatomyositis. Eur J Dermatol. 2010: 20; 1-3.

・Seki M, Kimura H, Mori A, Shimada A, Yamada Y, Maruyama K, Hayashi Y, Agematsu K, Morio T, Yachie A, Kato M. Prominent eosinophilia but less eosinophil activation in a patient with Omenn syndrome. Pediatr Int. 2010: 52; e196-199.

・Shiba N, Kanazawa T, Park MJ, Okuno H, Tamura K, Tsukada S, Hayashi Y, Arakawa H. NOCH1 mutation in a female with myeloid/NK cell precursor acute leukemia. Pediatr Blood Cancer. 2010: 55; NOTCH1 1406-1409.

・Shiba N, Kato M, Park MJ, Sanada M, Ito E, Fukushima K, Sako M, Arakawa H, Ogawa S, Hayashi Y. Leukemia. CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome. Leukemia. 2010: 24; 1090-1092.

・Tsuchida M, Ohara A, Manabe A, Kumagai M, Shimada H, Kikuchi A, Mori T, Saito M, Akiyama M, Fukushima T, Koike K, Shiobara M, Ogawa C, Kanazawa T, Noguchi Y, Oota S, Okimoto Y, Yabe H, Kajiwara M, Tomizawa D, Ko K, Sugita K, Kaneko T, Maeda M, Inukai T, Goto H, Takahashi H, Isoyama K, Hayashi Y, Hosoya R, Hanada R. Tokyo Children’s Cancer Study Group. Long-term results of Tokyo Children’s Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999. Leukemia. 2010: 24; 383-396.

2009

・Arakawa H, Kobayashi Y. Genetics: Childhood Allergy and Epigenetics International Review of Asthma: 2009: 11; 44-53.

・Fukami M, Nishimura G, Homma K, Nagai T, Hanaki K, Uematsu A, Ishii T, Numakura C, Sawada H, Nakacho M, Kowase T, Motomura K, Haruna H, Nakamura M, Ohishi A, Adachi M, Tajima T, Hasegawa Y, Hasegawa T, Horikawa R, Fujieda K, Ogata T. Cytochrome P450 Oxidoreductase Deficiency: Identification and Characterization of Biallelic Mutations and Genotype-Phenotype Correlations in 35 Japanese Patients. J Clin Endocrinol Metab, 2009, 94; 1723-1731.

・Ikeuchi Y, Kobayashi Y, Arakawa H, Suzuki M, Tamura K, Morikawa A. Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome. Pediatr Nephrol. 2009: 24; 489-495.

・Kobayashi T, Inoue Y, Otani T, Morikawa A, Kobayashi T, Takeuchi K, Saji T, Sonobe T, Ogawa S, Miura M, Arakawa H. Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy for Kawasaki disease. Pediatr Infect Dis J. 2009: 28: 498-502.

・Masutani S, Seki M, Taketazu M, Senzaki H. Successful management of the persistent pulmonary hypertension of the newborn with transposition of the great arteries by restricted patency of the ductus arteriosus: a simple and rational novel strategy. Pediatr Cardiol. 2009: 30; 1003-1005.

・Miyamoto T, Doi Y, Ikeda K, Kobayashi T, Kobayashi T. Repair of narrowed coronary sinus without connecting superior vena cava. Asian Cardiovasc Thorac Ann. 2009: 17; 186-188.

・Mochizuki H, Muramatsu R, Hagiwara S, Takami S, Mizuno T, Arakawa H. Relationship between bronchial hyperreactivity and asthma remission during adolescence. Ann Allergy Asthma Immunol. 2009: 103; 201-205.

・Mochizuki H, Muramatsu R, Tadaki H, Mizuno T, Arakawa H, Morikawa A. Effects of skin care with shower therapy on children with atopic dermatitis in elementary schools. Pediatr Dermatol. 2009: 26; 223-225.

・Mochizuki H, Tadaki H, Takami S, Muramatsu R, Hagiwara S, Mizuno T, Arakawa H. Evaluation of out-in skin transparency using a colorimeter and food dye in patients with atopic dermatitis. Br J Dermatol. 2009: 160; 972-979.

・Mochizuki H, Todokoro M, Arakawa H. RS virus-induced inflammation and the intracellular glutathione redox state in cultured human airway epithelial cells. Inflammation. 2009: 32; 252-264.

・Seki M, Kato T, Masutani S, Matsunaga T, Senzaki H. Pulmonary arterial hypertension associated with gastroesophageal reflux in a 2-month-old boy with down syndrome. Circ J. 2009: 73; 2352-2354.

・Senzaki H, Kumakura R, Ishido H, Masutani S, Seki M, Yoshiba S. Left atrial systolic force in children: reference values for normal children and changes in cardiovascular disease with left ventricular volume overload or pressure overload. J Am Soc Echocardiogr. 2009: 22; 939-946.

・Tadaki H, Arakawa H, Mizuno T, Suzuki T, Takeyama K, Mochizuki H, Tokuyama K, Yokota S, Morikawa A. Double-stranded RNA and TGF-alpha promote MUC5AC induction in respiratory cells. J Immunol. 2009: 182; 293-300.

・Tadaki H, Arakawa H, Sugiyama M, Ozawa K, Mizuno T, Mochizuki H, Morikawa A. Association of cord blood cytokine levels with wheezy infants in the first year of life. Pediatr Allergy Immunol. 2009: 20; 227-233.

・Tadaki H, Mochizuki H, Muramastu R, Hagiwara S, Takami S, Mizuno T, Arakawa H. Effect of bronchoconstriction on exhaled nitric oxide levels in healthy and asthmatic children. Ann Allergy Asthma Immunol. 2009: 102; 469-474.

・Yoshizawa Y, Watanabe M, Ohki Y, Tokuyama K, Mayuzumi H, Takahashi Y, Morikawa A. Periventricular echodensity measured with the integrated backscatter system: From a qualitative assessment to a quantitative approach. Neonatology. 2009: 96; 219-225.

2008

・Amano H, Nagai Y, Kowase T, Ishikawa O. Cutaneous necrosis induced by extravasation of arginine monohydrochloride. Acta Derm Venereol. 2008: 88; 310-311.

・Connor FL, Hyman PE, Faure C, Tomomasa T, Pehlivanov N, Janosky J, Rudolph C, Liem O, di Lorenzo C. Interobserver variability in antroduodenal manometry. Neurogastroenterol Motil. 2008: 21; 500- 507.

・Hashimoto Y, Muramatsu K, Uemura T, Harada R, Sato T, Okamoto K, Harada A. Neuron-specific and inducible recombination by Cre recombinase in the mouse. Neuroreport. 2008: 19; 621-624.

・Iijima A, Sato K, Yano K, Kato M, Kozawa K, Furuta N. Emission factor for antimony in brake abrasion dusts as one of the major atmospheric antimony sources. Environ Sci Technol. 2008: 42; 2937- 2942.

・Iijima A, Tago H, Kumagai K, Kato M, Kozawa K, Sato K, Furuta N. Regional and seasonal characteristics of emission sources of fine airborne particulate matter collected in the center and suburbs of Tokyo, Japan as determined by multielement analysis and source receptor models. J Environ Monit. 2008: 10; 1025-1032.

・Ishige T, Kaneko H, Suzuki T, Miyazawa R, Tomomasa T, Kubota M, Morikawa A. Pemphigus vulgaris as a possible cause of protein-losing gastroenteropathy: a case report. J Paediatr Child Health. 2008: 44; 143-145.

・Kitamura A, Tsukaguchi H, Maruyama K, Shono A, Iijima K, Kagami S, Doi T. Steroid-resistant nephrotic syndrome. Kidney Int. 2008: 74; 1209-1215.

・Koitabashi M, Kanazawa T, Tamura K, Tsukada S, Suzuki M, Morikawa A, Ogawa C, Hirado J. A novel mutation of the SMARCB1 gene in a case of extrarenal malignant rhabdoid tumor: Letter to the editor. Cancer Genet Cytogenet. 2008: 181; 67-68.

・Mauryama K. Different clinical manifestation of HCMV in preterm twins: Methodological approach: Reply. Pediatr Int. 2008: 50; 142.

・Miyazawa R, Tomomasa T, Kaneko H, Arakawa H, Shimizu N, Morikawa A. Effects of pectin liquid on gastroesophageal reflux disease in children with cerebral palsy. BMC Gastroenterol. 2008: 8; 11.

・Mizoguchi F, Mochizuki H, Muramatsu R, Tadaki H, Kobayashi T, Arakawa H, Onigata K, Morikawa A. Relationship between the Serum Leptin Concentration and Bronchial Hyperresponsiveness in Pre-school Children. Pediatr Allergy Immunol. 2008: 21; doi.org/10.1089/pai.2007.019.

・Morita Y, Kogure H, Sandoh M, Kawashima G, Sato Y, Nanba S, Shoda Y, Suzuki T, Shiono M, Shiobara M, Kato M, Kozawa K, Noda M, Okabe N, Kimura H. An imported dengue fever case by dengue virus 3 (DENV-3) infection in Gunma, Japan. Jpn J Infect Dis. 2008: 61; 90-92.

・Mukai H, Hokari Y, Seki T, Takao T, Kubota M, Matsuo Y, Tsukagoshi H, Kato M, Kimura H, Shimonishi Y, Kiso Y, Nishi Y, Wakamatsu K, Munekata E. Discovery of mitocryptide-1, a neutrophil-activating cryptide from healthy porcine heart. J Biol Chem. 2008: 283; 30596-30605.

・Muramatsu K, Hashimoto Y, Uemura T, Kunii M, Harada R, Sato T, Morikawa A, Harada A. Neuron-specific recombination by Cre recombinase inserted into the murine tau locus. Biochem Biophys Res Commun. 2008: 370; 419-423.

・Nakazato Y, Tanaka R, Seki E, Iijima M, Kojima M, Yoshizumi M, Kato M, Kimura H, Kozawa K, Goya T. Differential diagnosis of primary versus metastatic pulmonary adenocarcinomas using gene mutation analyses: a case report. J Thorac Oncol. 2008: 3; 931-934.

・Ohki Y, Mayuzumi H, Tokuyama K, Yoshizawa Y, Arakawa H, Mochizuki H, Morikawa A. Hepatocyte Growth Factor Treatment Improves Alveolarization in a Newborn Murine Model of Bronchopulmonary Dysplasia. Neonatology. 2008: 95; 332-338.

・Ohki Y, Yoshizawa Y, Watanabe M, Kuwashima M, Morikawa A. Complications of percutaneously inserted central venous catheters in Japanese neonates. Pediatr Int. 2008: 50; 636-639.

・Okazaki K, Kondo M, Kato M, Kakinuma R, Nishida A, Noda M, Kimura H. Elevation of High-Mobil- ity Group Box 1 Concentration in Asphyxiated Neonates. Neonatology. 2008: 94; 105-109.

・Okazaki K, Kondo M, Kato M, Kakinuma R, Nishida A, Noda M, Taniguchi K, Kimura H. Serum cytokines/chemokines profiles in neonates with meconium aspiration syndrome. Pediatrics. 2008: 121; e748-e753.

・Okazaki K, Kondo M, Kato M, Nishida A, Takahashi H, Noda M, Kimura H. Temporal alterations in concentrations of sera cytokines/chemokines in sepsis due to group B streptococcus infection in a neonate. Jpn J Infect Dis. 2008: 61; 382-385.

・Shimada A, Kato M, Tamura K, Hirato J, Kanegane H, Takechi Y, Park M, Sotomatsu M, Hatakeyama S, Hayashi Y. Hemophagocytic lymphohistiocytosis associated with uncontrolled inflammatory cytokinemia and cytokinemia was caused by systemic anaplastic large cell lymphoma: a case report and review of the literature. J Pediatr Hematol Oncol. 2008: 30; 785-787.

・Shimoyama S, Kobayashi T, Inoue Y, Mochizuki H, Hamajima A, Kobayashi T, Hatakeyama S, Morikawa A. Left displacement of the mediastinum determines the imbalance in the pulmonary vascular bed and lung volume in children with pectus excavatum. Pediatr Surg Int. 2008: 24; 549-553.

・Suzuki M, Takahashi A, Toki F, Hatori R, Tomomasa T, Morikawa A, Kuwano H. The effects of intestinal ischemia on colonic motility in conscious rats. J Gastroenterol. 2008: 43; 767-773.

・Suzuki T, Arakawa H, Mizuno T, Muramatsu K, Tadaki H, Takizawa T, Mochizuki H, Tokuyama K, Matsukura S, Morikawa A. Differential Regulation of Eotaxin Expression by Dexamethasone in Normal Human Lung Fibroblasts. Am J Respir Cell Mol Biol. 2008: 38; 707-714.

・Tadaki H, Mochizuki H, Muramastu R, Hagiwara S, Mizuno T, Arakawa H, Morikawa A. A flow- and pressure-controlled offline method of exhaled nitric oxide measurement in children. Ann Allergy Asthma Immunol. 2008: 100; 308-313.

・Tajiri H, Tomomasa T, Yoden A, Konno M, Sasaki M, Maisawa S, Sumazaki R, Shimizu T, Toyoda S, Etani Y, Nakacho M, Ushijima K, Kobayashi A. Japanese Society for Pediatric Inflammatory Bowel Disease Efficacy and safety of azathioprine and 6-mercaptopurine in Japanese pediatric patients with ulcerative colitis: a survey of the Japanese Society for Pediatric Inflammatory Bowel Disease. Digestion. 2008: 77:150-154.

・Tamura K, Kanazawa T, Tsukada S, Kobayashi T, Kawamura M, Morikawa A. Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2008: 51; 662-668.

・Wang J, Mochizuki H, Todokoro M, Arakawa H, Morikawa A. Does leukotriene affect intracellular glutathione redox state in cultured human airway epithelial cells?. Antioxid Redox Signal. 2008: 10; 821- 828.

・Yamaguchi T, Kimura H, Kurabayashi M, Kozawa K, Kato M. Interferon- enhances human eosinophil effector functions induced by granulocyte-macrophage colony-stimulating factor or interleukin-5. Immunol Lett. 2008: 118; 88-95.

・Yoshizumi M, Nakamura T, Kato M, Ishioka T, Kozawa K, Wakamatsu K, Kimura H. Release of cytokines/chemokines and cell death in UVB-irradiated human keratinocytes, HaCaT. Cell Biol Int. 2008: 32; 1405-1411.

2007

・Kobayashi T, Kimura H, Okada Y, Inoue Y, Kobayashi T, Shinohara M, Morikawa A. Increased CD11b expression on polymorphonuclear leucocytes and cytokine profiles in patients with Kawasaki disease. Clin Exp Immunol. 148:112-118,2007.

・Sugiyama M, Arakawa H, Ozawa K, Mizuno T, Mochizuki H, Tokuyama K, Morikawa A. Early-life risk factors for occurrence of atopic dermatitis during the first year. Pediatrics. 119(3):716-23. 2007

・Mayuzumi H, Ohki Y, Tokuyama K, Sato A, Mizuno T, Arakawa H, Mochizuki H, Morikawa A. Age-Related Difference in the Persistency of Allergic Airway Inflammation and Bronchial Hyperresponsiveness in a Murine Model of Asthma. Int Arch Allergy Immunol.143(4):255-262. 2007

・Shiba N, Tamura K, Kanazawa T, Tsukada S, Koitabashi M, Morikawa A. Novel three-way t(4;5;22)(q35;q31;q13) in acute megakaryoblastic leukemia. Cancer Genet Cytogenet. 174(1):82-3. 2007

・Kobayashi T, Inoue Y, Tamura K, Morikawa A, Kobayashi T. External validation of a scoring system to predict resistance to intravenous immunoglobulin. J Pediatr. 150(4):e37. 2007

・Miyazawa R, Tomomasa T, Kaneko H, Arakawa H, Morikawa A. Effect of formula thickened with reduced concentration of locust bean gum on gastroesophageal reflux. Acta Paediatr. 96(6):910-4. 2007

・Kobayashi K, Katsuya Y, Abdulah R, Fujisawa C, Nagamine T, Morikawa A, Murakami M, Kodama H, Koyama H. Direct Analysis of Ceruloplasmin in Human Blood Serum by HPLC/Inductively Coupled Plasma-Mass Spectrometry for the Diagnosis of Wilson Disease. Biomedical Research on Trace Elements. 18(1):91-95. 2007

・Watanabe M, Ohki Y, Yoshizawa Y, Inoue Y, Tokuyama K, Morikawa A. Maturational Changes in Skin Color of Japanese Newborn Infants. Neonatology. 91:275-280. 2007

・Inoue Y, Kobayashi T, Morikawa A. Treatment of Kawasaki disease.N Engl J Med. 356(26):2746-7; author reply 2748. 2007″

・Shimizu Y, Dobashi K, Hisada T, Ono A, Todokoro M, Iiima H, Utugi M, Kakegawa S, Iizuka K, Ishizuka T, Morikawa A, Mori M. Acute impact of volcanic ash in asthma symptoms and treatment. International Journal of Immunopathology and Pharmacology. 20(2)(S2):9-14. 2007

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of nasopharyngeal bacterial flora. Variations in nasopharyngeal bacterial flora in schoolchildren and adults when administered antimicrobial agents.
J Infect Chemother. 13(4):235-54. 2007″

・Mukoyama T, Nishima S, Arita M, Ito S, Urisu A, Ebisawa M, Ogura H, Kohno Y, Kondo N, Shibata R, Hurusho M, Mayumi M, Morikawa A and Food Allergy Committee, Japanese Society of Pediatric Allergy and Clinical Immunology
Guidelines for diagnosis and management of pediatric food allergy in Japan.Allergol Int. 2007;56(4):349-61. 2007

・Morikawa A, Nishima S. THE JAPANESE SOCIETY OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY. New Japanese pediatric guidelines for the treatment and management of bronchial asthma.Pediatr Int. 49(6):1023-1031. 2007

・Tahakashi A, Hasegawa M, Sumazaki R, Suzuki M, Toki F, Suehiro T, Onigata K, Tomomasa T, Suzuki T, Matsui A, Morikawa A, Kuwano H. Gradual improvement of liver function after administration of uresodeoxycholic acid in an infant with a novel ABCB11 gene mutation with phenotypic continuum between BRIC2 and PFIC2. European Journal of Gastroenterology & Hepatology. 19(11):942-946. 2007

・Saotome C, Mochizuki H, Kobayashi T, Arakawa H, Tokuyama K, Koyama H, Morikawa A. Effect of medical treatments on an improvement of asthma in the early stage of life. Pediatric Asthma, Allergy & Immunology. 20:83-92.2007

2006

・Saitoh M, Shinkawa N, Shimada S, Segawa Y, Sadamasu K, Hasegawa M, Kato M, Kozawa K, Kuramoto T, Nishio O, Kimura H. Phylogenetic analysis of envelope glycoprotein (E1) gene of rubella viruses prevalent in Japan in 2004. Microbiol Immunol.50(3):179-85. 2006

・Roy BB, Jinno-Oue A, Shinagawa M, Shimizu A, Tamura K, Shimizu N, Tanaka A, Hoshino H. Isolation of the feline alpha1,3-galactosyltransferase gene, expression in transfected human cells and its phylogenetic analysis. Exp Zoolog B Mol Dev Evol.306(1):59-69. 2006

・Tamura K, Kanazawa T, Suzuki M, Shioya A, Morikawa A. Successful induction of immune tolerance by continuous infusion of recombinant factor VIII in a haemophilia A patient with high-inhibitor titres. Haemophilia. 12(1):100-2. 2006

・Takagi H, Hagiwara S, Hashizume H, Kanda D, Sato K, Sohara N, Kakizaki S, Takahashi H, Mori M, Kaneko H, Ohwada S, Ushikai M, Kobayashi K, Saheki T. Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis. J Hepatol.44(1):236-9 .2006

・Kobayashi T, Kobayashi T, Mayuzumi H, Morikawa A. Percutaneous hydrodynamic thrombectomy for congenital deep vein thrombosis in a neonate. Pediatr Cardiol. 27(1):170-4. 2006

・Mochizuki H, Arakawa H, Tokuyama K, Morikawa A. Effect of age on bronchial reactivity in children with asthma. J Asthma. 43(1):25-9. 2006

・Tamura K, Kanazawa T, Suzuki M, Koitabashi M, Ogawa C, Morikawa A. Successful rapid discontinuation of immunosuppressive therapy at molecular relapse after allogeneic bone marrow transplantation in a pediatric patient with myelodysplastic syndrome. Am J Hematol. 81(2):139-41. 2006

・Kitanaka S, Sato U, Maruyama K, Igarashi T. A compound heterozygous mutation in the BSND gene detected in Bartter syndrome type IV. Pediatr Nephrol.21(2):190-3. (2006)

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of upper respiratory tract bacterial flora: first report. Variations in upper respiratory tract bacterial flora in patients with acute upper respiratory tract infection and healthy subjects and variations by subject age. J Infect Chemother;12(2):83-96. 2006

・Foronjy RF, Mirochnitchenko O, Propokenko O, Lemaitre V, Jia Y, Inouye M, Okada Y, D’Armiento JM. Superoxide dismutase expression attenuates cigarette smoke- or elastase-generated emphysema in mice. Am J Respir Crit Care Med. 173(6):623-31. 2006

・Muramatsu R, Mochizuki H, Arakawa H, Tokuyama K, Morikawa A. Effect of inhaled histamine on airway epithelial cell swelling in ozone-exposed Guinea pigs. Respiration.73(5):673-9. 2006

・Wang J, Mochizuki H, Muramatsu R, Arakawa H, Tokuyama K, Morikawa A. Evaluation of bronchial hyperresponsiveness by monitoring of transcutaneous oxygen tension and arterial oxygen saturation during methacholine challenge in asthmatic children. J Asthma. 43(2):145-9. 2006

・Okazaki K, Nishida A, Kato M, Kozawa K, Uga N, Kimura H. Elevation of cytokine concentrations in asphyxiated neonates. Biol Neonate. 89(3):183-9. 2006

・Tsunekawa K, Onigata K, Morimura T, Kasahara T, Nishiyama S, Kamoda T, Mori M, Morikawa A, Murakami M. Identification and functional analysis of novel inactivating thyrotropin receptor mutations in patients with thyrotropin resistance. Thyroid. 16(5):471-9. 2006

・Kimura H, Yoshizumi M, Iijima M, Tsukagoshi T, Nishimura T, Kato M, Morita Y, Tanaka R, Kozawa K, Fujita M, Kojima M, Minakami H. Tuberculosis-like peritonitis due to an atypical Mycobacterium infection in a Japanese woman. Jpn J Infect Dis. 59(3):189-91. 2006

・Kobayashi T, Inoue Y, Takeuchi K, Okada Y, Tamura K, Tomomasa T, Kobayashi T, Morikawa A. Prediction of intravenous immunoglobulin unresponsiveness in patients with Kawasaki disease. Circulation. 113(22):2606-12. 2006

・Kato M, Kimura H, Seki M, Shimada A, Hayashi Y, Morio T, Kumaki S, Ishida Y, Kamachi Y, Yachie A. Omenn syndrome–review of several phenotypes of Omenn syndrome and RAG1/RAG2 mutations in Japan. Allergol Int.55(2):115-9. 2006

・Working Group of the Japanese Society for Pediatric Gastroenterology, Hepatology and Nutrition; Konno M, Kobayashi A, Tomomasa T, Kaneko H, Toyoda S, Nakazato Y, Nezu R, Maisawa S, Miki K. Guidelines for the treatment of Crohn’s disease in children. Pediatr Int. 48(3):349-52. 2006

・Muto Y, Sato S, Watanabe A, Moriwaki H, Suzuki K, Kato A, Kato M, Nakamura T, Higuchi K, Nishiguchi S, Kumada H, Ohashi Y; for the Long-Term Survival Study (LOTUS) Group. Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis. Hepatol Res. 35(3):204-14. 2006

・Inoue Y, Okada Y, Shinohara M, Kobayashi T, Kobayashi T, Tomomasa T, Takeuchi K, Morikawa A. A multicenter prospective randomized trial of corticosteroids in primary therapy for Kawasaki disease: clinical course and coronary artery outcome. J Pediatr. 149(3):336-341. 2006

・Yamaguchi T, Suzuki M, Kimura H, Kato M. Role of protein kinase C in eosinophil function. Allergol Int. 55(3):245-52. 2006

・Kondo N, Katsunuma T, Odajima Y, Morikawa A. A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children. Allergol Int. 55(3):287-93. 2006

・Wang J, Mochizuki H, Muramatsu R, Mizuno T, Arakawa H, Tokuyama K, Morikawa A. Effect of Aging on the Relationship between Asthma Severity and Bronchial Hyperresponsiveness in Children with Asthma. J Asthma. 43(8):607-12. 2006

・Adachi M, Ohta K, Morikawa A, Nishima S. [Asthma Insights & Reality in Japan 2005] Arerugi.55(10):1340-3. 2006

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 2. J Infect Chemother. ;12(5):305-30. 2006

・Miyazawa R, Tomomasa T, Kaneko H, Morikawa A. Effect of formula thickened with locust bean gum on gastric emptying in infants. J Paediatr Child Health. 42(12):808-12. 2006

・Kobayashi Y, Watanabe T, Inoue Y, Arakawa H, Mochizuki H, Tokuyama K, Morikawa A. CR8/194-A case of fulminated fatal disseminated Varicella Zoster virus infection with severe pulmonary damage. Paediatr Respir Rev.7S:S328. 2006

・Morikawa A. Asthma : What We learn from each other’s prpblems? The present state of asthma in Japan and Japanese Pediatric Guidelines for the Treatment and Management of Asthma(JPGTMA). Paediatric Respiratory Reviews.7S:S121-S122. 2006

・Tamura K. Detection of minimal residual disease : Clinical utility in myelodysplastic syndrome in children. Res. Adv. In Hematology 1:1-12. 2006

・Kanda K, Mizuno H, Sugiyama Y, Imamine H, Togari H, Onigata K. Clinical Significance of Heterozygous Carries Associated with Compensated Hypothyroidism in R450H, a Common Inactivating Mutation of the Thyrotropin Receptor Gene in Japanese. Endocrine 30:383-388. 2006

2005

・Tamura K, Oue A, Tanaka A, Shimizu N, Takagi H, Kato N, Morikawa A, Hoshino H. Efficient formation of vesicular stomatitis virus pseudotypes bearing the native forms of hepatitis C virus envelope proteins detected after sonication. Microbes Infect. 7(1):29-40. (2005)

・Kato M, Yamaguchi T, Tachibana A, Kimura H. Differential role of an atypical protein kinase C, PKC zeta, in regulation of human eosinophil and neutrophil functions. Int Arch Allergy Immunol. 137 Suppl 27-34. (2005)

・Kato M, Hayashi Y, Kimura H. Oxygen radicals in inflammation and allergy related to viral infections. Curr Drug Targets Inflamm Allergy. 4(4):497-501. (2005)

・Ohki Y, Tokuyama K, Mayuzumi H, Sato A, Koyama H, Takizawa T, Arakawa H,Mochizuki H, Morikawa A. Characteristic features of allergic airway inflammation in a murine model of infantile asthma. Int Arch Allergy Immunol. 138(1):51-8.9. (2005)

・Arakawa H, Yuhara Y, Todokoro M, Kato M, Mochizuki H, Tokuyama K, Kunimoto F, Morikawa A. Immunoadsorption therapy for a child with Guillain-Barre syndrome subsequent to Mycoplasma infection: a case study. Brain Dev. 27(6):431-3. (2005)

・Kato M, Yamaguchi T, Tachibana A, Suzuki M, Izumi T, Maruyama K, Hayashi Y,Kimura H. An atypical protein kinase C, PKC zeta, regulates human eosinophil effector functions. Immunology. 116(2):193-202. (2005)

・Shiojima T, Fujiki Y, Sagai H, Iyobe S, Morikawa A. Prevalence of Streptococcus pneumoniae isolates bearing macrolide resistance genes in association with integrase genes of conjugative transposons in Japan. Clin Microbiol Infect. 11(10):808-13. (2005)

・Kanazawa T,Ogawa C,Taketani T,Taki T,Hayashi Y,Morikawa A. TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease. Leuk Lymphoma46(12):1833-5 (2005)

・Nishima S,Furusho K,Morikawa A,Mochizuki H,Akasaka T,Sugimoto H,Ikebe T,Nisimuta T,Sekine K,Yamada M,Odajima H,Motomura C,Yamatodani A. Pranlukast Inhibits Exercise-Induced Bronchospasm in Asthmatic Children:A Randomized,Multicenter,Double-Blind,Placebo-Controlled Two-Period Crossover Trial. Pediatric asthma,Allergy&Immunology18(1):5-11(2005)

・Ishii Y,Takizawa T,Arakawa H,Saga R,Mochizuki H,Tokuyama K,Morikawa A. Hemorrhagic bullous lesions in Henoch-Schonlein purpura. Pediatr Int.47(6):694-7(2005)

・Takahashi A,Tomomasa T,Kaneko H,Hatori R,Ishige T,Suzuki M,Mochiki E,Morikawa A,Kuwano H. In vivo recording of colonic motility in conscious rats with deficiency of interstitial cells of Cajal,with special reference to the effects of nitric interstitial cells of Cajal,with special reference to the effects of nitric oxide on colonic motility. J Gastroenterol.40(11):1043-8(2005)

・Mochizuki H,Arakawa H,Tokuyama K,Morikawa A. Bronchial sensitivity and bronchial reactivity in children with cough variant asthma. Chest.128(4):2427-34(2005)

・Koyama H,Tokuyama K,Nishimura H,Mizuno T,Mayuzumi H,Ohki Y,Arakawa H,Mochizuki H,Morikawa A. Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma. Int Arch Allergy Immunol.138(3):189-96. (2005)

・Inoue Y,Mastuwaki Y,Shin SH,Ponikau JU.,Kita H Nonpathogenic,Environmental Fungi Induce Activation and Degranulation of Human Eosinophils. The Journal of Immunology175(8):5439-5447(2005)

・Tomizawa D,Aoki Y,Nagasawa M,Morio T,Kajiwara M,Sekine T,Shimizu N,Kato M,YachieA,Mizutani S. Novel adopted immunotherapy for mixde chimerism after unrelated cord blood transplantation in Omenn syndrome. Eur J Haematol75(5):441-444(2005)

・Wada T,Toma T,Okamoto H,Kasahara Y,Koizumi S,Agematsu K,Kimura H,Shimada A,Hayashi Y,Kato M,Yachie A. Oligoclonal Expansion of T lymphocytes with multiple second-site mutations leads to Omenn syndrome in a patient with RAG1-deficient severe combined immunodeficiency. Blood106(6):2099-2101(2005)

・Hussain S,Miyazawa R,Tomomasa T,Kaneko H,Takahashi A,Watanabe T,Arakawa H,Morikawa A. Possible involvement of adrenomedullin in lipopolysaccharide-induced small-intestinal motility changes in conscious rats. J Gastroenterol 40:1123-1129(2005)

・Kimura H,Sawada T,Oshima S,Kozawa K,Ishioka T,Kato M. Toxicity and Roles of Reactive Oxygen Species. Current Drug Tagets-Inflammation&Allergy 4:489-495(2005)

2004

・Kaneko H, Tomomasa T, Kubota Y, Todokoro M, Kato M, Miyazawa R, Suzuki T, Hatori Y, Kunimoto F, Yamamoto K, Morikawa A. Pharmacobezoar complicating treatment with sodium alginate. J Gastroenterol. 39(1):69-71. (2004)

・Watanabe M, Ono S, Okada Y, Inoue Y, Kobayashi T, Suzuki T, Sugiyama Y, Ishihara S, Morikawa A. Spontaneous closure of an unroofed coronary sinus. Pediatr Int. 46(6):722-5. (2004)

・Arakawa H,Morikawa A. The genetics of pollinosis. Clin Exp Allergy Revi 4:3-7 (2004)

・Fujiu T,Maruyama K,Koizumi T. Oral iron supplementation in preterm infants treated with erythropoietin. Pediatr Int 46:635-9(2004)

・Kato M,Kimura H. Respiratory syncytial virus induces inflammation in bronchial asthma;Role of eosinophils. Allergology Int 53:301-307 (2004)

・Suzuki M,Arakawa H,Kobayashi Y,Tamura K,Mochizuki H,Tokuyama K,Tamari M,Mao XQ,Shirakawa T,Izuhara K,Morikawa A. Signal Transducers and Activators of Transcription 6 (Stat6) Variants in childhood and adult asthma. Allergology Int 53:241-244(2004)

・Suzuki M,Arakawa H,Tamura K,Takizawa T,Mochizuki H,Tokuyama K,Tamari M,Mao XQ,Shirakawa T,Morikawa A. Dinucleotide reteat polymorphisms in the Signal transducers and activators of transcription 6 (Stat6) gene in allergic diseases. Allergology Int 53:235-240 (2004)

・Watanabe T, Tomomasa T, Kaneko H, Takahashi A, Hussain S, Morikawa A. Effect of endotoxin on colonic motilitiy in conscious rats. Kitakanto Med J 54(2):143-146 (2004)

・Kaneko H,Tomomasa T,Kubota Y,Todokoro M,Kato M,Miyazawa R,Suzuki T,Hatori Y,Kunimoto F,Yamamoto K,Morikawa A. Pharmacobezoar complicating treatment with sodium alginate. J Gastroenterol 39(1):69-71 (2004)

・Shinohara M,Shitara T,Hatakeyama S,Suzuki N,Maruyama K,Kobayashi T,Tsuchida Y. An infant with systemic hypertension,renal artery stenosis,and neruoblastoma. J Pediatr Surg 39(1):103-106 (2004)

・Hikima A, Mochizuki H, Oriuchi N, Endo K, Morikawa A. Semiquantitative analysis of interictal glucose metabolism between generalized epilepsy and localization related epilepsy. Ann Nucl Med. 18(7):579-84. (2004)

・Okada Y, Minakami H, Tomomasa T, Kato M, Inoue Y, Kozawa K, Kimura H, Morikawa A. Serum procalcitonin concentration in patients with Kawasaki disease. J Infect. 48(2):199-205. (2004)

・Todokoro M,Mochizuki H,Tokuyama K,Utsugi M,Dobashi K,Mori M,Morikawa A. Effect of ozone exposure on intracellular glutathione redox state in cultured human airway epithelial cells. Inflammation. 28(2):105-14. (2004)

・Ishii S, Yamada M, Satoh T, Monden T, Hashimoto K, Shibusawa N, Onigata K, Morikawa A, Mori M. Aberrant dynamics of histone deacetylation at the thyrotropin-releasing hormone gene in resistance to thyroid hormone. Mol Endocrinol. 18(7):1708-20. (2004)

・Takahashi A, Ogawa C, Kanazawa T, Watanabe H, Suzuki M, Suzuki N, Tsuchida Y, Morikawa A, Kuwano H. Remission induced by interferon alfa in a patient with massive osteolysis and extension of lymph-hemangiomatosis: a severe case of Gorham-Stout syndrome. J Pediatr Surg. 2005 40(3):E47-50. (2004)

・Miyazawa R,Tomomasa T,Kaneko H,Morikawa A. Effect of locust bean gum in anti-regurgitant milk on the regurgitation in uncomplicated gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 38(5):479-83. (2004)

・Kato M, Kita H, Tachibana A, Hayashi Y, Tsuchida Y, Kimura H. Dual signaling and effector pathways mediate human eosinophil activation by platelet-activating factor. Int Arch Allergy Immunol. 134 Suppl 37-43. Review. (2004)

・Takahashi A, Tomomasa T, Suzuki N, Kuroiwa M, Mochiki E, Tsuchida Y, Morikawa A, Kuwano H. Gastrointestinal manometric findings in a patient with total intestinal aganglionosis. J Pediatr Surg. 39(7):1104-6.

・Nako Y, Tomomasa T, Morikawa A. Risk of hypervitaminosis D from prolonged feeding of high vitamin D premature infant formula. Pediatr Int. 46(4):439-43. (2004)

・Tomomasa T, Kobayashi A, Ushijima K, Uchida K, Kagimoto S, Shimizu T, Tajiri H, Tahara T, Yoden A. Working Group of the Japanese Society for Pediatric, Gastroenterology,Hepatology and Nutrition. Guidelines for treatment of ulcerative colitis in children. Pediatr Int. 46(4):494-6 (2004).

・Morita Y, Maruyama S, Kabeya H, Nagai A, Kozawa K, Kato M, Nakajima T, Mikami T, Katsube Y, Kimura H. Genetic diversity of the dnaJ gene in the Mycobacterium avium complex. J Med Microbiol. 53(Pt 8):813-7. (2004)

2003

・Kimura H, Kato M, Ikeda M, Nagai A, Okada Y, Naito S, Oshima S, Taniguchi K, Kozawa K, Morikawa A. Sulfonated human immunoglobulin enhances CD16-linked CD11b expression on human neutrophils. Cell Biol Int. 27(11):913-9. (2003)

・Kimura H,Saitoh M,Miyakubo H,Yoshida H,Kato M,Nagai A,Kozawa K. Keratoconjunctivitis caused by echovirus type 13 in Japanese children. Pediatr Infect Dis J 22:758-759 (2003)

・Maruyama K,Shiojima T,Koizumi T. Sonographic detection of a malpositioned feeding tube causing esophageal perforation in a neonate. J Clin Ultrasound 31:108-10 (2003)

・Miyazawa R,Arakawa H,Tabata M,Tomomasa T,Okamoto M,Yoshizawa Y,Suzuki T,Ohki Y,Nishimura H,Kuwashima M,Takeuchi H,Morikawa A. Characterization of the Japanese scoring system for bronchial asthma in children. Kitakanto Med J 53(2):179-184 (2003)

・Morita Y,Kimura H,Nagata M,Tsuchiya H,Kato M,Kozawa K,Maruyama S. Cutaneous infection in a cat caused by Mycobacterium avium complex serovar 6. Vet Rec 152:120 (2003)

・Mochizuki M,Amemiya S,Kobayashi K,Kobayasi K,Shimura Y,Ishihara T,Nakagomi Y,Onigata K,Tamai S,Kasuga A,Nanazawa S. Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. Diabetes Care 26:843-847 (2003)

・Nako Y,Tachibana A,Fujiu T,Tomomasa T,Morikawa A. Neonatal thrombocytosis resulting from the maternal use of non-narcotic anti-schizophrenic drugs during pregnancy. Review Series,Psychiatry 1:7-9 (2003)

・Nishida T,Kimura H,Saitoh M,Shinohara M,Kato M,Fukuda S,Munemura T,Mikami T,Kawamoto A,Akiyama M,Kato Y,Nishi K,Kozawa K,Nishio O. Detection,quantitation,and phylogenetic analysis of noroviruses in Japanese oysters. Appl Environ Microbiol. 69(10):5782-6. (2003)

・Takizawa T,Ochiai W,Nakashima K,Taga T. Enhanced gene activation by Notch and BMP signaling cross-talk. Nucleic Acids Res 31(19):5723-31 (2003)

・Kobayashi T, Kobayashi T, Shinohara M, Tomomasa T, Morikawa A. Percutaneous hydrodynamic thrombectomy for femoral arterial thrombosis after arterial catheterization. Pediatr Cardiol. 24(4):409-11. (2003)

・Miyazawa R, Ikeuchi Y, Tomomasa T, Ushiku H, Ogawa T, Morikawa A. Determinants of prognosis of acute transverse myelitis in children. Pediatr Int. 45(5):512-6. Review. (2003)

・Shimada A, Maruyama K, Shitara T, Kato M, Cho K, Kobayashi T, Fujiu T, Tsuchida Y, Nishida A, Hayashi Y, Minakami H, Kozawa K, Kimura H. Proinflammatory cytokinemia associated with transient myeloproliferative disorder in Down syndrome. Biol Neonate. 2004:85(3):167-72. (2003)

・Tomomasa T, Kobayashi A, Kaneko H, Mika S, Maisawa S, Chino Y, Syou H, Yoden A, Fujino J, Tanikawa M, Yamashita T, Kimura S, Kanoh M, Sawada K, Morikawa A. Granulocyte adsorptive apheresis for pediatric patients with ulcerative colitis. Dig Dis Sci. 48(4):750-4. (2003)

・Tamura K, Suzuki M, Arakawa H, Tokuyama K, Morikawa A. Linkage and association studies of STAT6 gene polymorphisms and allergic diseases. Int Arch Allergy Immunol. 131(1):33-8. (2003)

・Kato M, Minakami H, Kuroiwa M, Kobayashi Y, Oshima S, Kozawa K, Morikawa A, Kimura H. Superoxide radical generation and Mn- and Cu-Zn superoxide dismutases activities in human leukemic cells. Hematol Oncol. 21(1):11-6. (2003)

・Suzuki M, Kato M, Kimura H, Fujiu T, Morikawa A. Inhibition of human eosinophil activation by a cysteinyl leukotriene receptor antagonist (pranlukast: ONO-1078). J Asthma. 40(4):395-404.(2003)

・Todokoro M, Mochizuki H, Tokuyama K, Morikawa A. Childhood cough variant asthma and its relationship to classic asthma. Ann Allergy Asthma Immunol. 90(6):652-9. (2003)

・Takizawa T, Kato M, Suzuki M, Tachibana A, Motegi Y, Fujiu T, Kimura H, Arakawa H, Mochizuki H, Tokuyama K, Morikawa A. Distinct isoforms of protein kinase C are involved in human eosinophil functions induced by platelet-activating factor. Int Arch Allergy Immunol. 131 Suppl 15-9. (2003)

・Suzuki M, Kato M, Hanaka H, Izumi T, Morikawa A. Actin assembly is a crucial factor for superoxide anion generation from adherent human eosinophils. J Allergy Clin Immunol. 112(1):126-33. (2003)

・Kobayashi Y, Arakawa H, Suzuki M, Takizawa T, Tokuyama K, Morikawa A. Polymorphisms of interleukin-4–related genes in Japanese children with minimal change nephrotic syndrome. Am J Kidney Dis. 42(2):271-6. (2003)

・Watanabe M, Ono S, Tomomasa T, Okada Y, Kobayashi T, Suzuki T, Morikawa A. Measurement of tricuspid annular diastolic velocities by Doppler tissue imaging to assess right ventricular function in patients with congenital heart disease. Pediatr Cardiol. 24(5):463-7. (2003)

・Okada Y, Shinohara M, Kobayashi T, Inoue Y, Tomomasa T, Kobayashi T, Morikawa A. Gunma Kawasaki Disease Study Group. Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children. J Pediatr. 143(3):363-7. (2003)

・Shiojima T, Ohki Y, Nako Y, Morikawa A, Okubo T, Iyobe S. Immediate control of a methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit. J Infect Chemother. 9(3):243-7. (2003)

・Morikawa A. Greetin from the President. International Journal Pediatric Otorhinolaryngology67:1267 (2003)

・Mochizuki H,Morikawa A. Airway inflammation in children with a chronic cough. International Journal Pediatric Otorhinolaryngology67:1267-1268 (2003)

2002

・Tachibana A, Kimura H, Kato M, Nako Y, Kozawa K, Morikawa A. Respiratory syncytial virus enhances the expression of CD11b molecules and the generation of superoxide anion by human eosinophils primed with platelet-activating factor. Intervirology. 45(1):43-51. (2002)

・Hashimoto M,Nishida A,Minakami H,Takashima Y,Kato M,Okada Y,Ogawa Y,Itoh S,Kimura H. Decreased expression of L-selectin on peripheral blood polymorphonuclear leukocytes in neonates with severe asphyxia. Biol Neonate 81:95-98 (2002)

・Hosoya M,Ushiku H,Arakawa H,Morikawa A. Low-voltage activity in EEG during acute phase of encephalitis predicts unfavorable neurological outcome. Brain Dev 24(3):161-5 (2002)

・Imashuku S,Teramura T,Ishi E,Kinugawa N,Kato M,Sako M,Kuriyama K,Hibi S. Intravenous immunoglobulin for hemophagocytic lymphohistiocytosis? J Clin Oncol 20(2):599-601 (2002)

・Kato M,Tachibana A,Kimura H,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Respiratory syncytial virus enhances expression of CD11b molecules and the generation of superoxide anion by human eosinophil primed with platelet-activating factor. Int Arch Allergy Immunol 128(S1):26 (2002)

・Maruyama K,Shinohara M,Hatakeyama S,Onigata K. Distal renal tubular acidosis associated with hypercalcemia and nephrocalcinosis in an infant. Pediatr Nephrol 17(11):977-978 (2002)

・Milla PJ,Cucchiara S,DiLorenzo C,Rivera NM,Rudolph C,Tomomasa T. Motility disorders in childhood: Working Group Report of the First World Congress of Pediatric Gastroenterology,Hepatology,and Nutrition. J Pediatr Gastroenterol Nutr 35 Suool 2:S187-95 (2002)

・Morikawa A. Pediatric bronchial asthma : A personal view. Current advances in pediatric asthma and other allergic Diseases. pp3-8 Jomo Newspaper Co (Maebashi) 2002

・Mochizuki H,Morikawa A. Ozone-induced airway damage and bronchial hyperresponsiveness. Current advances in pediatric asthma and other allergic Diseases. pp49-54 Jomo Newspaper Co (Maebashi) (2002)

・Kato M,Tachibana A,Kimura H,Morikawa A. Bronchial asthma and bronchiolitis induced by respiratory syncytial virus: role of eosinophils. In: Morikawa A Current advances in pediatric asthma and other allergic diseases. pp59-64 Jomo Newspaper Co (Maebashi) 2002

・Tokuyama K,Arakawa H,Yokoyama T,Ohki Y. Evaluation of allergic airway inflammation in immature animals.-A bacic approach to cure asthmatic children. Current advances in pediatric asthma and other allergic diseases. pp99-103 Jomo Newspaper Co (Maebashi) (2002)

・Arakawa H,Tamura K,Suzuki M. Novel dinucleotide repeat polymorphism in the first exon of the STAT6 gene is associated with allergic diseases. Current advances in pediatric asthma and other allergic diseases. pp127-132 Jomo Newspaper Co (Maebashi) 2002

・Shinohara M,Sone K,Kobayashi T,Tomomasa T,Morikawa A. Treatment of Kawasaki disease with predonisolone. Current advances in Pedeatric asthma and other allergic diseases pp163-167 Jomo Newspaper Co (Maebashi) (2002)

・Morita Y,Kimura H,Minakami H,Saitoh M,Kato M,Nagai A,Kozawa K. Acid-fast bacteria in the gastric contents of a neonate. Pediatr Infect Dis J. 21:987-988

・Nishimura H,Tokuyama K,Arakawa H,Ohki Y,Sato A,Kato M,Mochizuki H,Morikawa A. Airways responsiveness and airway remodeling after chronic exposure to procaterol and fenoterol in guinea pigs in vivo. Int Ahch Allergy Immunol 129:320-326 (2002)

・Ogawa T,Tomomasa T,Morikawa A. Developmental changes in cyclo-oxygenase mRNA induction by hypoxia in rat kidney. Pediatr Int 44(6):675-679 (2002)

・Okada Y,Fukasawa N,Tomomasa T,Inoue Y,Morikawa A. Atlanto-axial subluxation (Grisel’s sysndrome) associated with mumps. Pediatr Int 200 :44:192-194 (2002)

・Rappold GA,Fukami M,Niesler B,Schiller S,Zumkeller W,Bettendorf M,Heinrich U,Vlachopapadoupoulou E,Reinehr T,Onigata K,Ogata T. Deletions of the homeobox gene SHOX (short stature homeobox) are an important cause of growth failure in children with short stature. J Clin Endocrinol Metab 87(3):1402-6 (2002)

・Shimoda M,Morita S,Obata Y,Sotomaru Y,Kono T,Hatada I. Imprinting of a small nucleolar RNA gene on mouse chromosome 12. Genomics 79(4):483-486 (2002)

・Uemura A,Takizawa T,Ochiai W,Ynagagisawa M,Nakashima K,Taga T. Cardiortophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of stat3. Cytokine 18(1):1-7 (2002)

・Yamanouchi H,Yokoo H,Yuhara Y,Maruyama K,Sasaki A,Hirato J,Nakazato Y. An autopsy case of ornithine transcarbamylase deficiency. Brain Dev 24(2):91-4

・Yoshiuchi I,Yamagata K,Zhu Q,Tamada I,Takahashi Y,Onigata K,Takeda J,Miyagawa J,Matsuzawa Y. Identification of a gain-of-function mutation in the HNF-1β gene in a Japanese family with MODY. Diabetologia 45(1):154-5 (2002)

・Mochizuki H, Ohki Y, Arakawa H, Kato M, Tokuyama K, Morikawa A. Effect of inhaled indomethacin on distilled water-induced airway epithelial cell swelling. J Appl Physiol. 92(1):155-61. (2002)

・Ohki Y, Tokuyama K, Sato A, Nishimura H, Tabata M, Tomiyoshi K, Inoue T, Arakawa H, Kato M, Mochizuki H, Morikawa A. Maturational changes in airway remodeling after chronic exposure to ovalbumin in sensitized guinea pigs: role of cell renewal of airway resident cells. Pediatr Res 52(4):525-32. (2002)

・Miyazawa R, Tomomasa T, Kaneko H, Tachibana A, Ogawa T, Morikawa A. Prevalence of gastro-esophageal reflux-related symptoms in Japanese infants. Pediatr Int. 44(5):513-6.

・Maruyama K, Watanabe H, Onigata K
Reversible secondary pseudohypoaldosteronism due to pyelonephritis. Pediatr Nephrol. 17(12):1069-70. (2002)

・Kato M, Kimura H, Motegi Y, Tachibana A, Minakami H, Morikawa A, Kita H. Platelet-activating factor activates two distinct effector pathways in human eosinophils. J Immunol. 169(9):5252-9. (2002)

・Tachibana A, Kato M, Kimura H, Fujiu T, Suzuki M, Morikawa A. Inhibition by fenoterol of human eosinophil functions including beta2-adrenoceptor-independent actions. Clin Exp Immunol. 130(3):415-23. (2002)

・Ogawa T, Tomomasa T, Morikawa A. Developmental changes in cyclo-oxygenase mRNA induction by hypoxia in rat kidney. Pediatr Int. 44(6):675-9. (2002)

・Tonooka N, Tomura H, Takahashi Y, Onigata K, Kikuchi N, Horikawa Y, Mori M, Takeda J
High frequency of mutations in the HNF-1alpha gene in non-obese patients with diabetes of youth in Japanese and identification of a case of digenic inheritance. Diabetologia. 45(12):1709-12. (2002)

・Inoue Y, Kato M, Ohsuka T, Morikawa A. Successful treatment of a child with inferior vena cava thrombosis using a temporary inferior vena cava filter. Pediatr Cardiol. 23(1):74-6. (2002)

・Inoue Y, Tomomasa T, Okada Y, Morikawa A. Divided right atrium associated with extensive coronary vein abnormalities. Pediatr Cardiol. 23(1):68-70. (2002)

・Arakawa H, Takizawa T, Tokuyama K, Mochizuki H, Morikawa A. Efficacy of inhaled anticholinergics and anesthesia in treatment of a patient in status asthmaticus. J Asthma. 39(1):77-80. (2002)

・Tomomasa T,Ogawa T,Hikima A,Tabata M Kaneko H,Morikawa A
Developmental changes in cyclooxygenase mRNA expression in the gastric mucosa of rats. J Pediatr Gastroenterol Nutr. 34(2):169-73. (2002)

・Harigaya A,Nako Y,Morikawa A,Okano H,Takagi T. Premature infant with severe periventricular leukomalacia associated with a large placental chorioangioma: a case report. J Perinatol. 22(3):252-4.

・Okamoto M,Nako Y,Tachibana A,Fujiu T,Ohki Y,Tomomasa T,Morikawa A. Efficacy of phenytoin against hyponatremic seizures due to SIADH after administration of anticancer drugs in a neonate. J Perinatol. 22(3):247-8. (2002)

・Tokuyama K, Nishimura H, Iizuka K, Kato M, Arakawa H, Saga R, Mochizuki H, Morikawa A. Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo. Pharmacology. 64(4):189-95.

・Mirza ZN, Kato M, Kimura H, Tachibana A, Fujiu T, Suzuki M, Mochizuki H, Tokuyama K, Morikawa A. Fenoterol inhibits superoxide anion generation by human polymorphonuclear leukocytes via beta-adrenoceptor-dependent and -independent mechanisms. Ann Allergy Asthma Immunol. 88(5):494-500. (2002)

・Inoue Y, Tokuyama K, Nishimura H, Arakawa H, Kato M, Mochizuki H, Morikawa A. Effects of STA(2), a thromboxane A(2) mimetic, in inducing airflow obstruction and airway microvascular leakage in guinea pigs. Pharmacology. 65(2):62-8. (2002)

・Kowase T,Nakazato Y,Yoko-O H,Morikawa A,Kojima I. Immunohistochemical localization of growth factor-regulated channel (GRC) in human tissues. Endocr J. 49(3):349-55.

・Watanabe T, Tomomasa T, Kaneko H, Takahashi A, Tabata M, Hussain S, Morikawa A. Involvement of serotonin and nitric oxide in endotoxin-induced gastric motility changes in conscious rats. Dig Dis Sci. 47(6):1284-9.

・Fujiu T, Kato M, Kimura H, Tachibana A, Suzuki M, Nako Y, Morikawa A. Cellular adhesion is required for effector functions of human eosinophils via G-protein coupled receptors. Ann Allergy Asthma Immunol. 89(1):90-8. (2002)

・Takizawa T, Kato M, Kimura H, Suzuki M, Tachibana A, Obinata H, Izumi T, Tokuyama K, Morikawa A. Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor. J Allergy Clin Immunol. 110(2):241-8. (2002)

・Takada C, Kaneko H, Tomomasa T, Tsukada S, Kanazawa T, Sotomatsu M, Oshimoto K, Okamoto S, Asao T, Takahashi A, Morikawa A. Endosonographic diagnosis of pneumatosis cystoides intestinalis in infancy. Tech Coloproctol. 6(2):121-3. (2002)

・Mochizuki H, Morikawa A, Kurosawa M. Bronchial hyperresponsiveness in a patient with systemic mastocytosis. Respirology. 7(3):285-8. (2002)

・Honda S, Yamamoto K, Sekizuka M, Oshima Y, Nagai K, Hashimoto G, Kaneko H, Tomomasa T, Konno Y, Horiuchi R. Successful treatment of severe hyperammonemia using sodium phenylacetate powder prepared in hospital pharmacy. Biol Pharm Bull. 25(9):1244-6. (2002)

・Ohshima Y,Yamada A,Hiraoka M,Katamura K,Ito S,Hirao T,Akutagawa H,Kondo N,Morikawa A,Mayumi M. Early sensitization tu house dust mite is a major risk factor for subsequent development of bronchial asthma in Jaoanese infants with atopic dermatitis:results of a 4-year followup study. Ann Allergy Asthma Immunol89(3):265-270 (2002)

・Inoue Y,Shin SH,Ponikau JU,Kita H. The fungus,Alternaria,induces activation and degranulation of human eosinophils. J Allergy Clin Immunol 109:S165 (2002)

・Kato M,Suzuki M,Kimura H,Fujiu T,Tachibana A,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Activation of human eosinophils via G protein-coupled receptors: compared with neutrophils. J Allergy Clin Immunol 109:S324

・Suzuki M,Kato M,Kimura H,Tachibana A,Fujiu T,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Inhibitory effect of pranlukast,a cysteinyl leukotriene receptor-anatagonist,on eosinophil activation induced by platelet-activating factor. J Allergy Clin Immunol 109:S225 (2002)

2001

・Kaneko H, Tomomasa T, Inoue Y, Kunimoto F, Fukusato T, Muraoka S, Gonmori K, Matsumoto T, Morikawa A. Amatoxin poisoning from ingestion of Japanese Galerina mushrooms. J Toxicol Clin Toxicol. 39(4):413-6. (2001)

・Kato M, Kephart GM, Morikawa A, Gleich GJ. Eosinophil infiltration and degranulation in normal human tissues: evidence for eosinophil degranulation in normal gastrointestinal tract. Int Arch Allergy Immunol. 125 Suppl 55-8. Review. (2001)

・Kimura H, Shibata Y, Minakami H, Hashizume S, Oba H, Sakaguchi M, Otsuki K, Kozawa K,Kato M. Release of IL-4 and IL-5 from human peripheral blood mononuclear cells co-cultured with Japanese cedar pollen antigen in vitro. Cell Biol Int. 25(8):841-4. (2001)

・Imashuku S,Kuriyama K,Teramura T,Ishi E,Kinugawa N,Kato M,Sako M,Hibi S. Requirement of etoposide in the treatment of Epstein-Barr virus-associated Hemophagocytic lymphohistiocytosis. J Clin Oncol 19:2665-2673 (2001)

・Koyama H,Harigaya A,Nako Y,Kohama Y,Morikawa A. Risk of neonatal complications in gestational diabetes. Kitakanto Med J 52(2):107-111 (2001)

・Miyamoto J,Hasegawa Y,Ohnami N,Onigata K,Kinoshita E,Nishi Y,Tachibana K,Hasegawa T. Development of growth hormone and adrenocorticotropic hormone deficiencies in patients with prenatal or perinatla-onset hypothalamic hypopituitarism having invisinble or thin pituitiary stalk on magnetic resonance imaging. Endocr J 48:355-62 (2001)

・Ogata T,Onigata K,Hotsubo T,Matsuo N,Rappold G. Growth hormone and gonadotropin-releasing hormone analog therapy in haploinsufficiency of SHOX. Endocr J. 48:317-22 (2001)

・Ochiai W,Ynagisawa M,Takizawa T,Nakashima K,Taga T. Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3. Cytokine. 14:264-271 (2001)

・Saga R,Mochizuki H,Tokuyama K,Morikawa A. Relationship between bronchial hyperresponsiveness and development of asthma in wheezy infants. Chest 119(3):685-690 (2001)

・Takizawa T,Yanagisawa M,Ochiai W,Yasukawa K,Ishiguro T,Nakashima K,Taga T. Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3. Cytokine. 13(5):272-279 (2001)

・Takizawa T,Nakashima K,Namihira M,Ochiai W,Uemura A,Yanagisawa M,Fujita N,Nakao M,Taga T. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Developmental Cell 1:749-758 (2001)

・Yanagisawa M,Takizawa T,Ochiai W,Uemura A,Nakashima K,Taga T. Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins. Neurosci. Res 41:391-396 (2001)

・Yanagisawa M,Nakashima K,Takeda K,Ochiai W,Takizawa T,Ueno M,Takizawa M,Shibuya H,Taga T. Inhibition of BMP2-induced,TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. Genes Cells 6:1091-1100 (2001)

・Yanagisawa M,Nakashima K,Takizawa T,Ochiai W,Arakawa H,Taga T. Signaling crosstalk underlying synergistic induction of astrocyte differenciation by BMPs and IL-6 family of cytokines. FEBS Lett 489:139-143 (2001)

・Matsuura N,Yokota Y,Kazahari K,Sasaki N,Amemiya S,Ito Y,Fukushima N,Koike A,Igarashi Y,Hirano T,Sugihara S,Miki Y,Urakami T,Uchigata Y,Kanematsu S,Ohki Y,Takesue M,Hasegawa Y,Miyamoto S,Fujimoto M,Fujitsuka S,Mori T,Ogawa H,Uchiyama M,Onigata K,Tachibana K,Kikuchi N,Taketani T,Kohno H,Kasahara Y,Isshiki G,Tokuda M,Takahashi T,Kanzaki S,Yokota I,KidaK,Okada T,Nishiyama S,Masuda H,Kinugasa A,Nukada O. The Japanese Study Group of Insulin Therapy for Childhood and AdolescentDiabetes (JSGIT): initial aims and impact of the family history of type 1diabetes mellitus in Japanese children. Pediatr Diabetes. 2(4):160-169. (2001)

・Kasahara M, Ohwada S, Takeichi T, Kaneko H, Tomomasa T, Morikawa A, Yonemura K, Asonuma K, Tanaka K, Kobayashi K, Saheki T, Takeyoshi I, Morishita Y. Living-related liver transplantation for type II citrullinemia using a graft from heterozygote donor. Transplantation. 15:71(1):157-9. (2001)

・Ohki Y, Kato M, Kimura H, Nako Y, Tokuyama K, Morikawa A. Elevated type IV collagen in bronchoalveolar lavage fluid from infants with bronchopulmonary dysplasia. Biol Neonate. 79(1):34-8. (2001)

・Nishigori H, Tomura H, Tonooka N, Kanamori M, Yamada S, Sho K, Inoue I, Kikuchi N, Onigata K, Kojima I, Kohama T, Yamagata K, Yang Q, Matsuzawa Y, Miki T, Seino S, Kim MY, Choi HS, Lee YK, Moore DD, Takeda J
Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A. 16:98(2):575-80.

・Nakashima K,Takizawa T,Ochiai W,Yanagisawa M,Hisatsune T,Nakafuku M,Miyazono K,KishimotoT,Kageyama R,Taga T
BMP2-madiated alteration in the developmenta pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA. 2001 98:5868-5873 (2001)

・Tamura K, Arakawa H, Suzuki M, Kobayashi Y, Mochizuki H, Kato M, Tokuyama K, Morikawa A
Novel dinucleotide repeat polymorphism in the first exon of the STAT-6 gene is associated with allergic diseases. Clin Exp Allergy. 31(10):1509-14. (2001)

・Miyazawa R, Hikima A, Takano Y, Arakawa H, Tomomasa T, Morikawa A
Plasmapheresis in fulminant acute disseminated encephalomyelitis. Brain Dev. 23(6):424-6. (2001)

・Takahashi A, Suzuki N, Ikeda H, Kuroiwa M, Tomomasa T, Tsuchida Y, Kuwano H
Results of bowel plication in addition to primary anastomosis in patients with jejunal atresia. J Pediatr Surg. 36(12):1752-6. (2001)

・Mochizuki H, Shigeta M, Morikawa A
Development of bronchial hyperresponsiveness during childhood. J Asthma. 38(1):1-21. Review. (2001)

・Takizawa T, Arakawa H, Tokuyama K, Morikawa A
Identification of allergen fractions of wheat flour responsible for anaphylactic reactions to wheat products in infants and young children. Int Arch Allergy Immunol. 125(1):51-6. (2001)

・Tomomasa T, Kobayashi K, Kaneko H, Shimura H, Fukusato T, Tabata M, Inoue Y, Ohwada S, Kasahara M, Morishita Y, Kimura M, Saheki T, Morikawa A
Possible clinical and histologic manifestations of adult-onset type II citrullinemia in early infancy. J Pediatr. 138(5):741-3. (2001)

・Kaneko H, Tomomasa T, Watanabe T, Takahashi A, Tabata M, Hussein S, Morikawa A. Effect of vincristine on gastric motility in conscious rats. Dig Dis Sci. 46(5):952-9. (2001)

・Nako Y, Tachibana A, Fujiu T, Tomomasa T, Morikawa A. Neonatal thrombocytosis resulting from the maternal use of non-narcotic antischizophrenic drugs during pregnancy. Arch Dis Child Fetal Neonatal Ed. 84(3):F198-200 (2001)

・Nishimura H, Mochizuki H, Tokuyama K, Morikawa A. Relationship between bronchial hyperresponsiveness and development of asthma in children with chronic cough. Pediatr Pulmonol. 31(6):412-8.

・Okada Y, Kato M, Minakami H, Inoue Y, Morikawa A, Otsuki K, Kimura H. Reduced expression of flice-inhibitory protein (FLIP) and NFkappaB is associated with death receptor-induced cell death in human aortic endothelial cells (HAECs). Cytokine. 21:15(2):66-74.(2001)

・Inoue Y, Kimura H, Kato M, Okada Y, Morikawa A. Sera from patients with Kawasaki disease induce intercellular adhesion molecule-1 but not Fas in human endothelial cells. Int Arch Allergy Immunol. 125(3):250-5. (2001)

・Kono M, Mochizuki H, Arakawa H, Kato M, Tokuyama K, Morikawa A. Age-dependent relationship between bronchial hyperresponsiveness to methacholine and total serum IgE level in asthmatic children. Ann Allergy Asthma Immunol. 87(1):33-8. (2001)

・Nagashima T, Murakami M, Onigata K, Morimura T, Nagashima K, Mori M, Morikawa A. Novel inactivating missense mutations in the thyrotropin receptor gene in Japanese children with resistance to thyrotropin. Thyroid. 11(6):551-9 (2001)

・Tomomasa T,Ogawa T, Hikima A, Kobayashi Y, Nakano K, Fukabori Y, Morikawa A. Developmental changes in cyclooxygenase mRNA expression in the kidney of rats. Pediatr Nephrol. 16(8):618-622. (2001)

・Nishimura H, Tokuyama K, Inoue Y, Arakawa H, Kato M, Mochizuki H, Morikawa A. Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. Prostaglandins Other Lipid Mediat. 66(1):1-15. (2001)

・Koike H, Motooka M, Kanda T, Onigata K, Murakami M, Suzuki T, Kobayashi I. Detection of point mutation for human growth hormone in patients with anti-pituitary antibody positive type 1 diabetes mellitus. J Int Med Res. 29(5):397-408. (2001)

・Takahashi A, Tomomasa T, Kaneko H, Watanabe T, Tabata M, Morikawa H, Tsuchida Y, Kuwano H. Intestinal motility in an in vivo rat model of intestinal ischemia-reperfusion with special reference to the effects of nitric oxide on the motility changes. J Pediatr Gastroenterol Nutr. 33(3):283-8. (2001)

・Morikawa A,Maeda S,Shigeta M,Arakawa H,Tamura H,Kato M,Tokuyama K,Kuroume T. Low Molecular Weight Fraction of Dermatophagoides Farinae is Present in Sera of Patients with Bronchial Asthma. The Kitakanto Medical Journal51(4):255-259 (2001)

・Okada Y,Ono S,Tomomasa T,Inoue Y,Morikawa A. Balloon angioplasty in a patient with Kabuki Make-up syndrome. Pediatrics International43:694-696 (2001)

・Kimura H,Shibata Y,Minakami H,Hashizume S,Oba H,Sakaguchi M,Otsuki K,Kozawa K,Kato M. Release Of IL-4 and IL-5 from Human Peripheral Blood Mononuclear Cells Co-Cultured with Japanese Cedar Pollen Antigen in Vitro. Cell Biology International25(8):841-844 (2001)

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