研究業績

英文

2018

・Ito K, Takizawa T. Nuclear Architecture in the Nervous System: Development, Function, and Neurodevelopmental Diseases. Front Genet. 2018; 9: 308.

・Azad GK, Ito K, Sailaja BS, Biran A, Nissim-Rafinia M, Yamada Y, Brown DT, Takizawa T, Meshorer E. PARP1-dependent eviction of the linker histone H1 mediates immediate early gene expression during neuronal activation. J Cell Biol. 2018; 217(2): 473-481.

・Ito K, Noguchi A, Uosaki Y, Taga T, Arakawa H, Takizawa T. Gfap and Osmr regulation by BRG1 and STAT3 via interchromosomal gene clustering in astrocytes. Mol Biol Cell. 2018; 29(2): 202-219.

・Arakawa N, Takizawa T, Nishida Y, Yagi H, Arakawa H. Chronic recurrent ostemyelitis with systemic juvenile idiopathic arthritis. Kitakanto Med J. 2018; 68(3): 167-169.

・Yamato G, Shiba N, Yoshida K, Hara Y, Shiraishi Y, Ohki K, Okubo J, Park MJ, Sotomatsu M, Arakawa H, Kiyokawa N, Tomizawa D, Adachi S, Taga T, Horibe K, Miyano S, Ogawa S, Hayashi Y. RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis. Blood. 2018; 131(20): 2266-2270.

・Matsuo H, Yoshida K, Fukumura K, Nakatani K, Noguchi Y, Takasaki S, Noura M, Shiozawa Y, Shiraishi Y, Chiba K, Tanaka H, Okada A, Nannya Y, Takeda J, Ueno H, Shiba N, Yamato G, Handa H, Ono Y, Hiramoto N, Ishikawa T, Usuki K, Ishiyama K, Miyawaki S, Itonaga H, Miyazaki Y, Kawamura M, Yamaguchi H, Kiyokawa N, Tomizawa D, Taga T, Tawa A, Hayashi Y, Mano H, Miyano S, Kamikubo Y, Ogawa S, Adachi S. Recurrent CCND3 mutations in MLL-rearranged acute myeloid leukemia. Blood Adv. 2018; 2(21): 2879-2889.

・Inoue Y, Shimizu A, Suto M, Kishi C, Takahashi A, Yasuda M, Iijima M, Arakawa H, Ishikawa O. Cutaneous squamous cell carcinoma, thyroid cancer and Langerhans cell histiocytosis in a patient with X-linked recessive Mendelian susceptibility to mycobacterial diseases with a nuclear factor-κB essential modifier mutation. J Dermatol. 2018; 45(8): 1017-1019.

・Miura M, Kobayashi T, Kaneko T, Ayusawa M, Fukazawa R, Fukushima N, Fuse S, Hamaoka K, Hirono K, Kato T, Mitani Y, Sato S, Shimoyama S, Shiono J, Suda K, Suzuki H, Maeda J, Waki K; and The Z-score Project 2nd Stage Study Group, Kato H, Saji T, Yamagishi H, Ozeki A, Tomotsune M, Yoshida M, Akazawa Y, Aso K, Doi S, Fukasawa Y, Furuno K, Hayabuchi Y, Hayashi M, Honda T, Horita N, Ikeda K, Ishii M, Iwashima S, Kamada M, Kaneko M, Katayama H, Kawamura Y, Kitagawa A, Komori A, Kuraishi K, Masuda H, Matsuda S, Matsuzaki S, Mii S, Miyamoto T, Moritou Y, Motoki N, Nagumo K, Nakamura T, Nishihara E, Nomura Y, Ogata S, Ohashi H, Okumura K, Omori D, Sano T, Suganuma E, Takahashi T, Takatsuki S, Takeda A, Terai M, Toyono M, Watanabe K, Watanabe M, Yamamoto M, Yamamura K. Association of Severity of Coronary Artery Aneurysms in Patients With Kawasaki Disease and Risk of Later Coronary Events. JAMA Pediatr. 2018; 172(5): e180030.

・Ishige T, Igarashi Y, Hatori R, Tatsuki M, Sasahara Y, Takizawa T, Arakawa H. IL-10RA Mutation as a Risk Factor of Severe Influenza-Associated Encephalopathy: A Case Report. Pediatrics. 2018, Jun, 141(6): pii: e20173548.

・Uehara T, Ishige T, Hattori S, Yoshihashi H, Funato M, Yamaguchi Y, Takenouchi T, Kosaki K. Three patients with DeSanto-Shinawi syndrome: Further phenotypic delineation. Am J Med Genet A. 2018; Jun, 176(6): 1335-1340.

・Ichinomiya K, Maruyama K, Koizumi A, Inoue F, Fukuda K, Kaburagi K, Miyakawa Y; Neonatal Research Network of Japan. Comparison of neurodevelopmental outcomes between monochorionic and dichorionic twins with birth weight ≤ 1500g in Japan: a register-based cohort study. J Perinatol. 2018; 38(10): 1407-1413.

・Nishizawa T, Ohki Y, Urano H Suzuki T, Kuwashima M. Knotted transpyloric tube in an infant, a patient report. Pediatr Int. 2018; 60(3): 310-311.

・Ishiyama A, Muramatsu K, Uchino S, Sakai C, Matsushima Y, Makioka N, Ogata T, Suzuki E, Komaki H, Sasaki M, Mimaki M, Goto YI, Nishino I. NDUFAF3 variants that disrupt mitochondrial complex I assembly may associate with cavitating leukoencephalopathy. Clin Genet. 2018; 93(5): 1103-1106.

・Motojima T, Fujii K, Ohashi H, Arakawa H. Catathrenia in Pitt-Hopkins syndrome associated with 18q interstitial deletion. Pediatr Int. 2018; 60(5): 479-481.

・Ashraf S, Kudo H, Rao J, Kikuchi A, Widmeier E, Lawson JA, Tan W, Hermle T, Warejko JK, Shril S, Airik M, Jobst-Schwan T, Lovric S, Braun DA, Gee HY1, Schapiro D, Majmundar AJ, Sadowski CE, Pabst WL, Daga A, van der Ven AT, Schmidt JM, Low BC, Gupta AB, Tripathi BK, Wong J, Campbell K, Metcalfe K, Schanze D, Niihori T, Kaito H, Nozu K, Tsukaguchi H, Tanaka R, Hamahira K, Kobayashi Y, Takizawa T, Funayama R, Nakayama K, Aoki Y, Kumagai N, Iijima K, Fehrenbach H, Kari JA, El Desoky S, Jalalah S, Bogdanovic R, Stajić N, Zappel H, Rakhmetova A, Wassmer SR, Jungraithmayr T, Strehlau J, Kumar AS, Bagga A, Soliman NA, Mane SM, Kaufman L, Lowy DR, Jairajpuri MA, Lifton RP, Pei Y, Zenker M, Kure S, Hildebrandt F. Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment. Nat Commun. 2018; 11(1); e004486.

・Hamajima E, Noda M, Nai E, Akiyama S, Ikuta Y, Obana N, Kawaguchi T, Hayashi K, Oba K, Yoshida T, Katori T, Kokaji M. Therapy with propylthiouracil for T3-predominant neonatal Graves’ disease: A case report. Clin Pediatr Endocrinol. 2018; 27(3): 165-169.

・Wada A, Muramatsu K, Sunaga Y, Mizuno T, Takei M, Ogasawara S, Uchida M, Tsukida K, Tashiro M. Brainstem infarction associated with HHV-6 infection in an infant. Brain Dev. 2018;40(3): 242-246.

・Itoh-Nagato N, Inoue Y, Nagao M, Fujisawa T, Shimojo N, Iwata T, J-OIT grouph. Desensitization to a whole egg by rush oral immunotherapy improves the quality of life of guardians: A multicenter, randomized, parallel-group, delayed-start design study. Allergol Int. 2018; 67: 209-216.

・Seki M, Powers JC, Maruyama S, Zuriaga MA, Wu CL, Kim L, Johnson, Poidomani A, Wang T, Muñoz E, Rajan S, Park JY, Walsh K, Recchia FA. Acute and chronic increases of circulating follistatin-like protein 1 normalize energy substrate metabolism in pacinginduced
heart failure. Circ Heart Fail. 2018; 11(1): e004486.

2017

・Arakawa H, Hamazaki Y, Kohno Y, Ebisawa M, Kondo N, Nishima S, Nishimuta T, Morikawa A, The Japanese Society of Pediatric Allergy and Clinical Immunology. The Japanese Society of Allergology. Japanese guidelines for childhood asthma 2017. Allergol Int. 2017; 66(2): 190-204.

・Fukazawa R, Kobayashi T, Mikami M, Saji T, Hamaoka K, Kato H, Suzuki H, Tsuda E, Ayusawa M, Miura M, Ebata R, Kobayashi T, Yashiro M, Ogawa S. Nationwide Survey of Patients With Giant Coronary Aneurysm Secondary to Kawasaki Disease 1999-2010
in Japan. Circulation J. 2017; 82(1);239-246.

・Hara Y, Shiba N, Ohki K, Tabuchi K, Yamato G, Park MJ, Tomizawa D, Kinoshita A, Shimada A, Arakawa H, Saito AM, Kiyokawa N, Tawa A, Horibe K, Taga T, Adachi S, Taki T, Hayashi Y. Prognostic impact of specific molecular profiles in pediatric acute megakaryoblastic leukemia in non-Down syndrome. Genes Chromosomes Cancer. 2017; 56(5); 394-404.

・Hatori R. Tomomasa T, Ishige T, Tatsuki M, Arakawa H. Fecal retention in childhood: Evaluation.on ultrasonography. Pediatr Int. 2017; 59(4): 462-466.

・Hazama K. Shiihara T, Tsukagoshi H, Hasegawa S,Dowa Y, Watanabe M. A case of mumps-related acute encephalopathy with biphasic seizures and late reduced diffusion. Brain & Development. 2017-Oct; 39(9): 808-810.

・Hosoi K. Ohtsuka Y, Fujii T, Kudo T, Matsunaga N, Tomomasa T, Tajiri H, Kunisaki R, Ishige T, Yamada H, Arai K, Yoden A, Ushijima K, Aomatsu T, Nagata S, Uchida K, Takeuchi K, Shimizu T. Treatment with infliximab for pediatric Crohn’s disease: Nationwide survey of Japan. J Gastroenterol Hepatol. 2017; 32(1); 114-119.

・Ikeda K, Takizawa T, Naito S, Nakamura K, Sasaki T, Kumagai K, Kobayashi T, Arakawa H. Safety and Efficacy of Catheter Ablation for Pediatric Ventricular Tachyarrhythmia. THE KITAKANTO MEDICAL JOURNAL 2017; 67(4): 287-290.

・Ishige T. Tomomasa T, Hatori R, Tatsuki M, Igarashi Y, Sekine K, Arakawa H. Temporal Trend of Pediatric Inflammatory Bowel Disease: Analysis of National Registry Data 2004 to 2013 in Japan. J Pediatr Gastroenterol Nutr. 2017; 65(4):e80-e82.

・Ishii Y, Miyamoto T, Nakajima K,Tanaka K,Ikeda K,Seki M, Shimoyama S, Kobayashi T, Arakawa H. Usefulness of Percutaneous Transluminal Pulmonary Artery Balloon Angioplasty after Bilateral Pulmonary Artery Banding: Prevention against Additional Surgical Interventions. Interv Cardiol J. 2017; 3(2): 1-7.

・Kobayashi Y. Aizawa A, Takizawa T, Igarashi K, Hatada I and Arakawa H. Changes in DNA methylation in naïve T helper cells regulate the pathophysiological state in minimal-change nephrotic syndrome. BMC Research Notes. 2017- 15;10(1):480.

・Lardelli RM, Schaffer AE, Eggens VRC, Zaki MS, Grainger S, Sathe S, Nostrand ELV, Schlachetzki Z, Rosti B, Akizu N, Scott E, Heckman LD, Rosti RO, Dikoglu E, Gregor A, G-Gamboa A, Musaev D, Mande R, Widjaja A, Shaw TL, \Markmiller S, M-Valencia I, Davies JH, de Meirleir L, Kayserili H, Altunoglu U, Freckmann ML, Warwick L, Chitayat D, çağlayan AO, Bilguvar K, Per H, Fagerberg C, Kibaek M, Aldinger KA, Manchester D, Matsumoto N, Muramatsu K, Saitsu H, Shiina M, Ogata K, Foulds N, Dobyns WB, Chi N, Traver D, Spaccini L, Bova SM, Gabriel SB, Gunel M, Valente EM, Bennett EJ, Yeo GW, Baas F, L-Andersen J, Gleeson JG. Biallelic Mutations in the 3’ Exonuclease TOE1 Cause Pontocerebellar Hypoplasia and Uncover a Role in snRNA Processing. Nature Genetics. 2017; 49(3): 457-464.

・Suzuki T. Sasahara Y, Kikuchi A, Kakuta H, Kashiwabara T, Ishige T, Nakayama Y, Tanaka
M, Hoshino A, Kanegane H, Abukawa D, Kure S. Targeted Sequencing and mmunological Analysis Reveal the Involvement of Primary Immunodeficiency Genes in Pediatric IBD: a Japanese Multicenter Study. J Clin Immunol. 2017; 37(1):67-79.

・Yamato G, Shiba N, Yoshida K, Shiraishi Y, Hara Y, Ohki K, Okubo J, Okuno H, Chiba K, Tanaka H, Kinoshita A, Moritake H, Kiyokawa N, Tomizawa D, Park MJ, Sotomatsu M, Taga T, Adachi S, Tawa A, Horibe K, Arakawa H, Miyano S, Ogawa S, Hayashi Y. ASXL2 mutations are frequently found in pediatric AML patients with t(8;21)/ RUNX1-RUNX1T1 and associated with a better prognosis. Genes Chromosomes Cancer. 2017; 56(5): 382-393.

・Yamato G, Yamaguchi H, Handa H, Shiba N, Kawamura M, Wakita S, Inokuchi K, Hara Y, Ohki K, Okubo J, Park MJ, Sotomatsu M, Arakawa H, Hayashi Y. Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia. Genes Chromosomes Cancer. 2017; 56(11):800-809.

・Ichinomiya K. Maruyama K, Inoue T, Koizumi A, Inoue F, Fukuda K, Yamazaki Y, Arakawa H. Perinatal Factors Affecting Serum Hepcidin Levels in Low-Birth-Weight Infants. Neonatology. 2017;112(2):180-186.

・Kamata A, Muramatsu K, Sawaura N, Makioka N, Ogata T, Kuwashima M, Arakawa H. Demyelinating Demyelinating neuropathy in a 6-year-old girl with autism spectrum disorder. Pediatr Int. 2017; 59(8):951-954.

・Kawashima J, Okuno H, Shiba N, Yoshida K, Shiraishi Y, Hara Y, Yamato G, Iijima M, Kaburagi T, Kanazawa T, Ohki K, Horibe K, Miyano S, Ogawa S, Hayashi Y, Arakawa H. Whole-Exome Sequencing in a Pediatric Patient with Relapsed/Refractory Burkitt Leukemia Resistant to Conventional Chemotherapy. Arch Paediatr Dev Pathol. 2017; 1(1): 1001.

・Maruyama K. Serum α -fetoprotein concentration in extremely low-birthweight infants. Pediatr Int. 2017; 59(2):159-162.

・Muramatsu K, Sawaura N, Ogata T, Makioka N, Tomita K, Motojima T, Ida K, Hazama K, Arakawa H. Efficacy and tolerability of levetiracetam for pediatric refractory epilepsy. Brain Dev. 2017; 39(3): 231-235.

・Oyanagi T, Takizawa T, Aizawa A,Solongo O, Yagi H, Nishida Y, Koyama H, Saitoh A, Arakawa H. Suppression of MUC5AC expression in human bronchial epithelial cells by interferon-γ . Allergol Int. 2017 Jan;66(1):75-82.

・Yoshimura A, Yuan J. -H. , Hashiguchi A, Hiramatsu Y, Ando M, Higuchi Y, Nakamura T, Okamoto Y, Matsumura K, Hamano T, Sawaura N, Shimatani Y, Kumada S, Okumura Y, Miyahara J, Yamaguchi Y, Kitamura S, Haginoya K, Mitsui J, Ishiura H, Tsuji S, Takashima H. Clinical and mutational spectrum of Japanese patients with Charcot-Marie-Tooth disease caused by GDAP1 variants. Clinical Genetics. 2017; 92(3): 274-280.

2016

・Hatori R, Tomomasa T, Ishige T, Tatsuki M, Arakawa H., Evaluation of fecal retention via ultrasonography in childhood., Pediatr Int, 2016, Epub ahead of print. Ito K, Sanosaka T, Igarashi K, Ideta-Otsuka M, Aizawa A, Uosaki Y, Noguchi A, Arakawa H, Nakashima K, Takizawa T. Identification of genes associated with the astrocyte-specific gene Gfap during astrocyte differentiation. Sci Rep, 2016, Apr, 4, 23903.

・Kobayashi T, Kobayashi T, Fuse S, Sakamoto N, Mikami M, Ogawa S, Hamaoka K, Arakaki Y, Nakamura T, Nagasawa H, Kato T, Jibiki T, Iwashima S, Yamakawa M, Ohkubo T, Shimoyama S, Aso K, Sato S, Saji T; Z Score Project Investigators, A New Z Score Curve of the Coronary Arterial Internal Diameter Using the Lambda-Mu-Sigma Method in a Pediatric Population, J Am Soc Echocardiogr, 2016, Aug, 29, 8, 794-801.

・Li L, Ohtsu Y, Nakagawa Y, Masuda K, Kojima I, Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms, Endocr J, 2016, Aug, 63, 8, 715-25.

・Narumi S, Amano N, Ishii T, Katsumata N, Muroya K, Adachi M, Toyoshima K, Tanaka Y, Fukuzawa R, Miyako K, Kinjo S, Ohga S, Ihara K, Inoue H, Kinjo T, Hara T, Kohno M, Yamada S, Urano H, Kitagawa Y, Tsugawa K, Higa A, Miyawaki M, Okutani T, Kizaki Z, Hamada H, Kihara M, Shiga K, Yamaguchi T, Kenmochi M, Kitajima H, Fukami M, Shimizu A, Kudoh J, Shibata S, Okano H, Miyake N, Matsumoto N, Hasegawa T. SAMD9 mutations cause a novel multisystem disorder, MIRAGE syndrome, and are associated with loss of chromosome 7. Nat Genet, 2016, Jul, 48, 7, 792-7.

・Onouchi Y, Fukazawa R, Yamamura K, Suzuki H, Kakimoto N, Suenaga T, Takeuchi T, Hamada H, Honda T, Yasukawa K, Terai M, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Yoshiyama M, Miyashita R, Murata Y, Fujino A, Ozaki K, Kawasaki T, Abe J, Seki M, Kobayashi T, Arakawa H, Ogawa S, Hara T, Hata A, Tanaka T, Variations in ORAI1 Gene Associated with Kawasaki Disease, PLoS One, 2016, Jan, 11, 1, e0145486.

・Saleem MA, Kobayashi Y, Cell biology and genetics of minimal change disease.,
F1000Research(F1000 Faculty Rev) (doi: 10.12688/f1000research.7300.1), 2016, 5, 412.
Seki M, Kuwata S, Kurishima C, Nakagawa R, Inuzuka R, Sugimoto M, Saiki H, Iwamoto Y, Ishido H, Masutani S, Senzaki H, Mechanism of aortic root dilation and cardiovascular function in tetralogy of Fallot, Pediatr Int, 2016, May, 58, 5, 323-30.

・Seki M, LaCanna R, Powers JC, Vrakas C, Liu F, Berretta R, Chacko G, Holten J, Jadiya P, Wang T, Arkles JS, Copper JM, Houser SR, Huang J, Patel VV, Recchia FA. Class I Histone Deacetylase Inhibition for the Treatment of Sustained Atrial Fibrillation, J Pharmacol Exp Ther, 2016, Sep, 358, 3, 441-9.

・Shiba N, Ohki K, Kobayashi T, Hara Y, Yamato G, Tanoshima R, Ichikawa H, Tomizawa D, Park MJ, Shimada A, Sotomatsu M, Arakawa H, Horibe K, Adachi S, Taga T, Tawa A, Hayashi Y, High PRDM16 expression identifies a prognostic subgroup of pediatric acute myeloid leukemia correlated to FLT3-ITD, MLL-PTD, and NUP98-NSD1, British Journal of Haematology, 2016, Feb. 172, 4, 581-591.

・Shiba N, Yoshida K, Shiraishi Y, Okuno Y, Yamato G, Hara Y, Nagata Y, Chiba K, Tanaka H, Terui K, Kato M, Park MJ, Ohki K, Shimada A, Takita J, Tomizawa D, Kudo K, Arakawa H, Adachi S, Taga T, Tawa A, Ito E, Horibe K, Sanada M, Miyano S, Ogawa S, Hayashi Y. Whole-exome sequencing reveals the spectrum of gene mutations and the clonal evolution patterns in paediatric acute myeloid leukaemia, British Journal of Haematology, 2016, Nov. 175, 3, 476-489.

・Sugimoto M, Saiki H, Tamai A, Seki M, Inuzuka R, Masutani S, Senzaki H, Ventricular fibrogenesis activity assessed by serum levels of procollagen type III N-terminal amino peptide during the staged Fontan procedure, J Thorac Cardiovasc Surg, 2016, Jun, 151, 6, 1518-26.

・Suzuki T., Miyake N., Tsurusaki Y., Okamoto N., Alkindy A., Inaba A., Sato M., Ito S., Muramatsu K., Kimura S., Ieda D., Saitoh S., Hiyane M., Suzumura H., Yagyu K., Shiraishi H., Nakajima M., Fueki N., Habata Y., Ueda Y., Komatsu Y., Yan K., Shimoda K., Shitara Y., Mizuno S., Ichinomiya K., Sameshima K., Tsuyusaki Y., Kurosawa K., Sakai Y., Haginoya K., Kobayashi Y., Yoshizawa C., Hisano M., Nakashima M., Saitsu H., Takeda S., Matsumoto N. Molecular genetic analysis of 30 families with Joubert syndrome. Clin Genet 2016: 90: 526-535. doi: 10.1111/cge.12836.

・Takagi M, Takahashi M, Ohtsu Y, Sato T, Narumi S, Arakawa H, Hasegawa T, A novel mutation in HESX1 causes combined pituitary hormone deficiency without septo optic dysplasia phenotypes, Endocr J, 2016, Apr, 63, 4, 405-10.

・Takahashi Y, Sano R, Kominato Y, Kubo R, Takahashi K, Nakajima T, Takeshita H, Ishige T. A case of sudden unexpected infant death involving a homozygotic twin with the thermolabile CPT2 variant, accompanied by rotavirus infection and treatment with an antibiotic containing pivalic acid. Leg Med (Tokyo), 2016, 22: 13-19.

・Yoshizawa C, Kobayashi Y, Ikeuchi Y, Tashiro M, Kakegawa S, Watanabe T, Goto Y, Nakanishi K, Yoshikawa N, Arakawa H. Congenital nephrotic syndrome with a novel NPHS1 mutation. Pediatrics International 58(11): 1211-1242. 2016.

2015

・Hagiwara S, Nakayama Y, Tagawa M, Arai K, Ishige T, Murakoshi T, Sekine H, Abukawa D,Yamada H, Inoue M, Saito T, Kudo T, Seki Y., Pediatric Patient and Parental Anxiety and Impressions Related to Initial Gastrointestinal Endoscopy: A Japanese Multicenter Questionnaire Study., Scientifica, 2015, Aug, epub.

・Hamano K, Nakagawa Y, Ohtsu Y, Li L, Medina J, Tanaka Y, Masuda K, Komatsu M, Kojima I., Lactisole inhibits the glucose-sensing receptor T1R3 expressed in mouse pancreatic β-cells., J Endocrinol., 2015, Jul, 226(1), 57-66.

・Ishige T,, Yagi H, Tatsuki M, Hatori R, Nishida Y, Takizawa T, Arakawa H., Endoscopic findings in the acute phase of food protein-induced enterocolitis syndromae., Pediatr Allergy Immunol, 2015, Feb, 26(1), 90-1.

・Jo A, Mitani S, Shiba N, Hayashi Y, Hara Y, Takahashi H, Tsukimoto I, Tawa A, Horibe K, Tomizawa D, Taga T, Adachi S, Yoshida T, Ichikawa H., High expression of EVI1 and MEL1 is a compelling poor prognostic marker of pediatric AML, Leukemia, 2015, May, 29(5), 1076-83. Kato M, Suzuki K, Yamada Y, Maruyama K, Hayashi Y, Mochizuki H, Virus detection and cytokine profile in relation to age among acute exacerbations of childhood asthma., Allergology
International, 2015, 67(9), 64-70.

・Kobayashi Y, Saleem MA, Hemopexin in Minimal Change Nephrotic Syndrome. In Kaneko K editor. Molecular mechanisms in the pathogenesis of idiopathic nephrotic syndrome, Springer Japan, pp13-23, 2015.

・Kojima I, Nakagawa Y, Ohtsu Y, Hamano K, Medina J, Nagasawa M., Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cells., J Diabetes Investig. , 2015, May, 6(5), 256-63.

・Sano H, Ohki K, Park MJ, Shiba N, Hara Y, Sotomatsu M, Tomizawa D, Taga T, Kiyokawa N, Tawa A, Horibe K, Adachi S, Hayashi Y., CSF3R and CALR mutations in paediatric myeloid disorders and the association of CSF3R mutations with translocations, including t(8; 21), British Journal of Haematology, 2015, Aug, 170(3), 391-7.

・Tajiri H,, Nishi J, Ushijima K, Shimizu T, Ishige T, Shimizu M, Tanaka H, Brooks S., A role for fosfomycin treatment in children for prevention of haemolytic-uraemic syndrome accompanying Shiga toxin-producing Escherichia coli infection., Int J Antimicrob Agents., 2015, Nov, 46(5), 586-9.

2014

・Akatsuka J, Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes. The ratio of glycated albumin to hemoglobin A1c measured in IFCC units accurately represents the glycation gap Endocr J 2014 Nov; Epub ahead of print.

・Hagiwara S, Mochizuki H, Muramatsu R, Koyama H, Yagi H, Nishida Y, Kobayashi T, Sakamoto N,Takizawa T, Arakawa H. Reference values for Japanese children’s respiratory resistance using the LMS method. Allergol Int. 2014 Mar; 63(1)113-9.

・Ichinomiya K, Ichinomiya K, Inoue F, Koizumi A, Inoue T, Fujiu T, Maruyama K. Problems with using total serum bilirubin as a criterion for phototherapy in extremely low-birthweight infants Pediatr Int. 2014 Oct; 56(5)731-4.

・Inamura N, Kubota A, Ishii R, Ishii Y, Kawazu Y, Hamamichi Y, Yoneda A, Kawahara H, Okuyama H, Kayatani F. Efficacy of the circulatory management of an antenatally diagnosed congenital diaphragmatic hernia: outcomes of the proposed strategy. Pediatr Surg Int. 2014 Sep; 30(9)889-94.

・Ishige T, Yagi H, Tatsuki M, Hatori R, Nishida Y, Takizawa T, Arakawa H. Endoscopic Findings in the Acute Phase of Food Protein-induced Enterocolitis Syndrome. Pediatr Allergy Immunol. 2015 Feb. 26(1) 90-1

・Ishii Y, Inamura N, Kayatani F, Iwai S, Kawata H, Arakawa H, Kishimoto H. Evaluation of bilateral pulmonary artery banding for initial palliation in single-ventricle neonates and infants: risk factors for mortality before the bidirectional Glenn procedure. Interact Cardiovasc Thorac Surg. 2014 Nov;19(5)807-11.

・Kojima I, Nakagawa Y, Ohtsu Y, Medina A, Nagasawa M. Sweet Taste-Sensing Receptors Expressed in Pancreatic β-Cells: Sweet Molecules Act as Biased Agonists. Endocrinol Metab(Seoul). 2014 Mar; 29(1)12-9.

・Kojima I, Nakagawa Y, Ohtsu Y, Hamano K, Medina J, Nagasawa M. Return of the Glucoreceptor:Glucose Activates the Glucose-sensing Receptor T1R3 and Facilitates Metabolism in Pancreatic β-cells J Diabetes Investig Epub. 2014; Dec 15.

・Matsuo H, Kajihara M, Tomizawa D, Watanabe T, Saito AM, Fujimoto J, Horibe K, Kodama K,Tokumasu M, Itoh H, Nakayama H, Kinoshita A, Taga T, Tawa A, Taki T, Shiba N, Ohki K, Hayashi Y, Yamashita Y, Shimada A, Tanaka S, Adachi S. EVI1 overexpression is a poor prognostic factor in pediatric patients with mixed lineage leukemia-AF9 rearranged acute myeloid leukemia. Haematologica. 2014 Nov; 99(11)225-7.

・Miyamoto T, Ikeda K, Ishii Y, Kobayashi T. Rupture of a coronary artery aneurysm in Kawasaki disease: a rare case and review of the literature for the past 15 years. J Thorac Cardiovasc Surg.2014 Jun; 147(6): e67-9.

・Nakagawa Y, Ohtsu Y, Nagasawa M, Shibata H, Kojima I. Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3. Endocr J. 2014 Feb; 61(2)119-31.

・Ohtsu Y, Nakagawa Y, Nagasawa M, Takeda S, Arakawa H, Kojima I, Diverse signaling systems activated by the sweet taste receptor in human GLP-1-secreting cells. Mol Cell Endocrinol. 2014 Aug; 394(1-2)70-9.

・Shiba N, Ohki K, Park MJ, Sotomatsu M, Kudo K, Ito E, Sako M, Arakawa H, Hayashi Y. SETBP1 mutations in juvenile myelomonocytic leukaemia and myelodysplastic syndrome but not in paediatric acute myeloid leukaemia. Br J Haematol. 2014 Jan; 164(1)156-9.

・Shiba N, Funato M, Ohki K, Park MJ, Mizushima Y, Adachi S, Kobayashi M, Kinoshita A, Sotomatsu M, Arakawa H, Tawa A, Horibe K, Tsukimoto I, Hayashi Y. Mutations of the GATA2 and CEBPA genes in paediatric acute myeloid leukaemia. Br J Haematol. 2014 Jan; 164(1)142-5.

・Takahashi Y, Sano R, Nakajima T, Kominato Y, Kubo R, Takahashi K, Ohshima N, Hirano T,Kobayashi S, Shimada T, Tokue H, Awata S, Hirasawa S, Ishige T. Combination of postmortem mass spectrometry imaging and genetic analysis reveals very long-chain acyl-CoA dehydrogenase deficiency in a case of infant death with liver steatosis. Forensic Sci Int. 2014 9; Epub ahead of print.

・Yi SH, He XB, Rhee YH, Park CH, Takizawa T, Nakashima K, Lee S. HFoxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation. Development. 2014 Feb; 141(4)761-72.

・Yoshii T, Miyamoto T, Inui A, Tanaka Y, Yoshitake S, Seki M, Kobayashi T. Fontan completion following flow adjustable bilateral pulmonary artery banding. Int Heart J. 2014 Nov; 13(55(6))552-4.

2013

・Saitsu H, Nishimura T, Muramatsu K, Kodera H, Kumada S, Sugai K, Kasai-Yoshida E, Sawaura N, Nishida H, Hoshino A, Ryujin F, Yoshioka S, Nishiyama K, Kondo Y, Tsurusaki Y, Nakashima M, Miyake N, Arakawa H, Kato M, Mizushima N, Matsumoto N. De novo mutations in the autophagy gene encoding WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nature Genetics. 45(4):445-449. 2013 35.532

・Saitsu H, Nishimura T, Muramatsu K, Kodera H, Kumada S, Sugai K, Kasai-Yoshida E, Sawaura N, Nishida H, Hoshino A, Ryujin F, Yoshioka S, Nishiyama K, Kondo Y, Tsurusaki Y, Nakashima M, Miyake N, Arakawa H, Kato M, Mizushima N, Matsumoto N. De novo mutations in the autophagy gene encoding WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nature Genetics. 45(4):445-449. 2013

・Yoshida K, Toki T, Okuno Y, Kanezaki R, Shiraishi Y, Sato-Otsubo A, Sanada M, Park MJ, Terui K, Suzuki H, Kon A, Nagata Y, Sato Y, Wang R, Shiba N, Chiba K, Tanaka H, Hama A, Muramatsu H, Hasegawa D, Nakamura K, Kanegane H, Tsukamoto K, Adachi S, Kawakami K, Kato K, Nishimura R, Izraeli S, Hayashi Y, Miyano S, Kojima S, Ito E, Ogawa S.The landscape of somatic mutations in Down syndrome-related myeloid disorders. Nat Genet. 45(11):1293-9. 2013

・Shiraishi Y, Sato Y, Chiba K, Okuno Y, Nagata Y, Yoshida K, Shiba N, Hayashi Y, Kume H, Homma Y, Sanada M, Ogawa S, Miyano S. An empirical Bayesian ework for somatic mutation detection from cancer genome sequencing data. Nucleic Acids Res. 41(7):e89. 2013

・Shiba N, Ichikawa H, Taki T, Park MJ, Jo A, Mitani S, Kobayashi T, Shimada A, Sotomatsu M, Arakawa H, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y. NUP98-NSD1 gene fusion and its related gene xpression signature are strongly associated with a poor prognosis in pediatric acute myeloid leukemia. Genes Chromosomes Cancer. 52(7):683-93. 2013

・Yoshimi A, Kamachi Y, Imai K, Watanabe N, Nakadate H, Kanazawa T, Ozono S, Kobayashi R, Yoshida M, Kobayashi C, Hama A, Muramatsu H, Sasahara Y, Jakob M, Morio T, Ehl S, Manabe A, Niemeyer C, Kojima S. Wiskott-Aldrich syndrome presenting with a clinical picture mimicking juvenile myelomonocytic leukaemia. Pediatr Blood Cancer. 60(5):836-41. 2013

・Ohki Y, Maruyama K, Harigaya A, Kohno M, Arakawa H. Complications of peripherally inserted central venous catheter in Japanese neonatal intensive care units. Pediatr Int. 55(2):185-9. 2013

・Kobayashi T, Kobayashi T, Morikawa A, Ikeda K, Seki M, Shimoyama S, Ishii Y, Suzuki T, Nakajima K, Sakamoto N, Arakawa H. Efficacy of Intravenous Immunoglobulin Combined with Prednisolone Following Resistance to Initial Intravenous Immunoglobulin Treatment of Acute Kawasaki Disease. J Pediatr. 163:521-6. 2013

・Yoshimoto A, Miyamoto T, Ozaki S, Kobayashi T, Kobayashi T. Flow-adjustable bilateral pulmonary artery banding in the neonatal period for severe congenital heart diseases. Gen Thorac Cardiovasc Surg. 61:340-344. 2013

・Inuzuka R, Seki M, Sugimoto M, Saiki H, Masutani S, Senzaki H.  Pulmonary arterial wall stiffness and its impact on right ventricular afterload in patients with repaired tetralogy of fallot. Ann Thorac Surg. 96:1435-41. 2013

・Ishii Y, Inamura N, Kawazu Y, Kayatani F, Arakawa H. ‘I-shaped’ sign in the upper mediastinum: a novel potential marker for antenatal diagnosis of d-transposition of the great arteries. Ultrasound Obstet Gynecol. 41: 667–671, 2013

2012

・Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y. CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML). Blood. 15;119(11):2612-4. 2012. 10.558

・Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y.DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia. Br J Haematol. 156(3):413-414. 2012. 4.942

・Seki M, Kurishima C, Kawasaki H, Masutani S, Senzaki H. Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal aortic mechanical property. Eur J Cardiothorac Surg. 41(2):277-82. 2012 2.293

・Sekine K, Mochizuki H, Inoue Y, Kobayashi T, Suganuma E, Matsuda S, Arakawa H. Regulation of oxidative stress in patients with Kawasaki disease. Inflammation. 35(3):952-8. 2012 1.777

・Kobayashi T, Saji T, Otani T, Takeuchi K, Nakamura T, Arakawa H, Kato T, Hara T, Hamaoka K, Ogawa S, Miura M, Nomura Y, Fuse S, Ichida F, Seki M, Fukazawa R, Ogawa C, Furuno K, Tokunaga H, Takatsuki S, Hara S, Morikawa A; on behalf of the RAISE study group investigators. Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease (RAISE study): a randomised, open-label, blinded-endpoints trial. Lancet. 379:1613-1620. 2012 33.633

・N. G. Papadopoulos, H. Arakawa, K.-H. Carlsen, A. Custovic, J. Gern, R. Lemanske, P. Le Souef, M. Mäkelä, G. Roberts, G. Wong, H. Zar, C. A. Akdis, L. B. Bacharier, E. Baraldi, H. P. van Bever, J. de Blic, A. Boner, W. Burks, T. B. Casale, J. A. Castro-Rodriguez, Y. Z. Chen, Y. M. El-Gamal, M. L. Everard, T. Frischer, M. Geller, J. Gereda, D. Y. Goh, T. W. Guilbert, G. Hedlin, P. W. Heymann, S. J. Hong, E. M. Hossny, J. L. Huang, D. J. Jackson, J. C. de Jongste, O. Kalayci, N. Aït-Khaled, S. Kling, P. Kuna, S. Lau, D. K. Ledford, S. I. Lee, A. H. Liu, R. F. Lockey, K. Lødrup-Carlsen, J. Lötvall, A. Morikawa, A. Nieto, H. Paramesh, R. Pawankar, P. Pohunek, J. Pongracic, D. Price, C. Robertson, N. Rosario, L. J. Rossenwasser, P. D. Sly, R. Stein, S. Stick, S. Szefler, L. M. Taussig, E. Valovirta, P. Vichyanond, D. Wallace, E. Weinberg, G. Wennergren, J. Wildhaber, R. S. Zeiger. International consensus on (ICON) pediatric asthma. Allergy. 67(8):976-97. 2012 6.297

・Kobayashi Y, Aizawa A, Takizawa T, Yoshizawa C, Horiguchi H, Ikeuchi Y, Kakegawa S, Watanabe T, Maruyama K, Morikawa A, Hatada I, Arakawa H..DNA methylation changes between relapse and remission of minimal change nephrotic syndrome.Pediatr Nephrol. 27(12):2233-41. 2012 2.518

・Arakawa H, Yagi H, Koyama H, Nakajima N, Takizawa T. Characteristics and natural course of neonatal and infantile gastrointestinal milk allergy and the efficacy of oral immunotherapy. Clinical & Experimental Allergy Reviews, 12, 20–24 2012

・Onouchi Y, Ozaki K, Burns JC, Shimizu C, Terai M, Hamada H, Honda T, Suzuki H, Suenaga T, Takeuchi T, Yoshikawa N, Suzuki Y, Yasukawa K, Ebata R, Higashi K, Saji T, Kemmotsu Y, Takatsuki S, Ouchi K, Kishi F, Yoshikawa T, Nagai T, Hamamoto K, Sato Y, Honda A, Kobayashi H, Sato J, Shibuta S, Miyawaki M, Oishi K, Yamaga H, Aoyagi N, Iwahashi S, Miyashita R, Murata Y, Sasago K, Takahashi A, Kamatani N, Kubo M, Tsunoda T, Hata A, Nakamura Y, Tanaka T; Japan Kawasaki Disease Genome Consortium; US Kawasaki Disease Genetics Consortium. A genome-wide association study identifies three new risk loci for Kawasaki disease. Nature Genetics. 44(5):517-21.2012 35.532

・Doisaki S, Muramatsu H, Shimada A, Takahashi Y, Mori-Ezaki M, Sato M, Kawaguchi H, Kinoshita A, Sotomatsu M, Hayashi Y, Furukawa-Hibi Y, Yamada K, Hoshino H, Kiyoi H, Yoshida N, Sakaguchi H, Narita A, Wang X, Ismael O, Xu Y, Nishio N, Tanaka M, Hama A, Koike K, Kojima S.
Somatic mosaicism for oncogenic NRAS mutations in juvenile myelomonocytic leukemia. Blood 120: 1485-1488. 2012

・H Saitsu, T Nishimura, K Muramatsu,(3名共筆頭著者)H Kodera, S Kumada, K Sugai, E Kasai-Yoshida, N Sawaura, H Nishida, A Hoshino, F Ryujin, S Yoshioka, K Nishiyama, Y Kondo, Y Tsurusaki, M Nakashima, N Miyake, H Arakawa, M Kato, N Mizushima, N Matsumoto. De novo mutations in the autophagy gene WDR45 cause static encephalopathy of childhood with neurodegeneration in adulthood. Nature Genetics, 45, 445-449 (2013)

・Ishii Y, Inamura N, Kayatani F. Congenital aneurysm of the right atrial appendage in a fetus. Pediatr Cardiol. 33:1227-9. 2012

・J Takanashi, Y Takahashi, A Imamura, K Kodama, A Watanabe, K Tominaga, K Muramatsu, A.Barkovich. Late delirious behavior with 2009 H1N1 Influenza; mild autoimmune-mediated encephalitis Pediatrics 129(4): e1068-71 (2012)

・Kato M, Ishioka T, Kita H, Kozawa K, Hayashi Y, Kimura H. Eosinophil granular proteins damage bronchial epithelial cells infected with respiratory syncytial virus. Int Arch Allergy Immunol. 158 Suppl 1: 11-18. 2012

・K Maruyama, T Fujiu. Effects of prophylactic indomethacin on renal and intestinal blood flow in premature infants. Pediatr Int 2012;54:480-485.

・Kobayashi Y, Aizawa A, Takizawa T, Yoshizawa C, Horiguchi H, Ikeuchi Y, Gotoh T, Kakegawa S, Watanabe T, Morikawa A, Hatada I, Arakawa H. DNA Methylation Changes between Relapse and Remission of Minimal Change Nephrotic Syndrome. Pediat Nephrol 27: 2233-41. 2012

・Maruyama K, Fujiu T. Effects of prophylactic indomethacin on renal and intestinal blood flow in premature infants. Pediatr Int. 54: 480-485. 2012

・Nakamura K, Kato M, Sasaki A, Shiihara T, Hayasaka K. Respiratory syncytial virus-associated encephalopathy complicated by congenital myopathy. Pediatr Int. 54: 709-11. 2012

・Saiki H, Kojima T, Seki M, Matsutani S, Senzaki H. Marked disparity in mechanical wall properties between ascending and descending aorta in patients with tetralogy of Fallot. Eur J Cardiothorac Surg. 41: 570-573. 2012

・Sailaja BS, Takizawa T, Meshorer E.Chromatin immunoprecipitation in mouse hippocampal cells and tissues.Methods Mol Biol. 809: 353-64. 2012

・Sano H, Shimada A, Taki T, Murata C, Park MJ, Sotomatsu M, Tabuchi K, Tawa A, Kobayashi R, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Hayashi Y. RAS mutations are frequent in FAB type M4 and M5 of acute myeloid leukemia, and related to late relapse: a study of the Japanese Childhood AML Cooperative Study Group. Int J Hematol 95 : 509-515. 201

・Seki M, Kurishima C, Kawasaki H, Matsutani S, Senzaki H. Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal abnormal aortic mechanical property. Eur J Cardiothorac Surg. 41: 277-282. 2012

・Shiba N, Hasegawa D, Park MJ, Murata C, Matsubara A, Ogawa C, Manabe A, Arakawa H, Ogawa S, Hayashi Y. CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia. Blood 119: 2612-2614. 2012

・Shiba N, Park MJ, Taki T, Takita J, Hiwatari M, Kanazawa T, Sotomatsu M, Ishii E, Arakawa H, Ogawa S, Hayashi Y. CBL mutations in infant acute lymphoblastic leukaemia. Br J Haematol . 156:672-674. 2012

・Shiba N, Taki T, Park MJ, Shimada A, Sotomatsu M, Adachi S, Tawa A, Horibe K, Tsuchida M, Hanada R, Tsukimoto I, Arakawa H, Hayashi Y. DNMT3A mutations are rare in childhood acute myeloid leukaemia, myelodysplastic syndromes and juvenile myelomonocytic leukaemia. Br J Haematol. 156: 413-414. 2012

・Shiihara T, Miyake T, Izumi S, Watanabe M, Kamayachi K, Kodama K, Nabetani M, Ikemiyagi M, Yamaguchi Y, Sawaura N. Serum and cerebrospinal fluid S100B, neuron-specific enolase , and total tau protein in acute encephalopathy with biphasic seizures and late reduced diffusion. Pediatr Int. 54: 52-55. 2012

・Shimoyama S, Kobayashi T. Evaluation of the effects of surgical correction of left mediastinal displacement in children with pectus excavatum on pulmonary perfusion, using minimal radiation exposure. Eur Res J. 40 (suppl 56): 5S. 2012

・Sugimoto M, Ishido H, Seki M, Matsutani S Tamai A, Senzaki H. Findings in the pulmonary vascular bed in the remote phase after Kawasaki disease. Am J Cardiol. 109: 1219-1222. 2012

・Takami S, Mizuno T, Oyanagi T, Tadaki H, Suzuki T, Muramatsu K, Takizawa T, Arakawa H.Glucocorticoids inhibit MUC5AC production induced by transforming growth factor-α in human respiratory cells. Allergol Int. 61(3): 451-9. 2012

・Takezaki S, Yamada M, Kato M, Park M, Maruyama K, Yamazaki Y, Chida N, Ohara O, Kobayashi I, Ariga T. Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. The Journal of Immunology. 189(3): 1521-1526. 2012.

・Tsurusaki Y, Kobayashi Y, Hisano M, Ito S, Doi H, Nakashima M, Saitsu H, Matsumoto N, Miyake N. The diagnostic utility of exome sequencing in Joubert syndrome and related disorders. J Hum Genet Oct 4. 2012

・Takezaki S, Yamada M, Kato M, Park M, Maruyama K, Yamazaki Y, Chida N, Ohara O, Kobayashi I, Ariga T. Chronic mucocutaneous candidiasis caused by a gain-of-function mutation in the STAT1 DNA-binding domain. J Immunol. 189: 15211-1526. 2012

・Tamai A, Kurishima C, Seki M, Masutani S, Taketazu M, Senzaki H. Stent Implantation for Effective Treatment of Refractory Chylothorax due to Superior Vena Cava Obstruction as a Complication of Congenital Cardiac Surgery. Clin Med Insights Cardiol. 6: 97-101. 2012

・Yamada Y, Kato M, Toki F, Watanabe M, Nishi A, Matsushita I, Hirato J, Hayashi Y. Eosinophilic gastrointestinal disorder in an infant with feeding dysfunction. Int Arch Allergy Immunol. 158 Suppl 1: 83-86. 201

・Y Hashimoto, K Muramatsu(2名共筆頭著者), M Kunii, S Yoshimura, M Yamada, T Sato, Y Ishida, R Harada, and A Harada Uncovering genes required for neuronal morphology by morphology-based gene trap screening with a revertible retrovirus vector. FASEB J. 2012 Nov; 26(11): 4662-74.

2011

・Ishii Y, Miyamoto T, Kobayashi T, Kobayashi T. Isolated Unilateral Agenesis of the Pulmonary Artery: Surgical Repair With an Artificial Graft. Pediatr Cardiol 2011:32:509-511.

・Ishioka T, Kimura H, Kita H, Obuchi M, Hoshino H, Noda M, Nishina A, Kozawa K, Kato M. Effects of respiratory syncytial virus infection and major basic protein derived from eosinophils in pulmonary alveolar epithelial cells (A549). Cell Biol Int. 35: 467-474, 2011.

・Kanai T, Ishiwata T, Kobayashi T, Sato H, Takizawa M, Kawamura Y, Tsujimoto H, Nakatani K, Ishibashi N, Nishiyama M, Hatai Y, Asao Y, Kobayashi T, Takeshita S, Nonoyama S. Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease. Circulation. 2011 Dec 20;124(25):2822-8.

・Kanai T, Ishiwata T, Kobayashi T, Sato H, Takizawa M, Kawamura Y, Tsujimoto H, Nakatani K, Ishibashi N, Nishiyama M, Hatai Y, Asao Y, Kobayashi T, Takeshita S, Nonoyama S. Ulinastatin, a urinary trypsin inhibitor, for the initial treatment of patients with Kawasaki disease. Circulation. 2011 Nov 21. [Epub ahead of print]

・Kanazawa T, Shiba N, Aizawa A, Okuno H, Tamura K, Tsukada S, Kumamoto T, Yamada S, Kobayashi Y, Arakawa H. Nelarabine Resistance of Childhood T-Cell lymphoblastic Leukemia/ Lymphoma Cells. Kitakanto Med J. 61:119-126. 2011

・Kato M, Tsukagoshi H, Yoshizumi M, Saitoh M, Kozawa K, Yamada Y, Maruyama K, Hayashi Y, Kimura H. Different cytokine profile and eosinophil activation are involved in rhinovirus-and RS virus-induced acute exacerbation of childhood wheezing. Pediatr Allergy Immunol. 22 : e87-94, 2011

・Kato M, Yamada Y, Maruyama K, Hayashi Y. Differential effects of corticosteroids on serum eosinophil cationic protein and cytokine production in rhinovirus- and respiratory syncytial virus-induced acute exacerbation of childhood asthma. Int Arch Allergy Immunol 155 Suppl 1:77-84, 2011

・Kato M, Yamada Y, Maruyama K, Hayashi Y. Differential effects of corticosteroids on serum eosinophil cationic protein and cytokine production in rhinovirus- and RS virus-induced acute exacerbation of childhood asthma. Int Arch Allergy Immunol. 155(Suppl 1): 77-84, 2011.

・Kawasaki H, Seki M, Saiki H, Masutani S, Senzaki H. Noninvasive assessment of left ventricular contractility in pediatric patients using the maximum rate of pressure rise in peripheral arteries. Heart Vessels. 2011 Jun 17. [Published online]

・Kobayashi T, Saji T, Otani T, Takeuchi K, Nakamura T, Arakawa H, Kato T, Hara T, Hamaoka K, Ogawa S, Miura M, Nomura Y, Fuse S, Ichida F, Seki M, Fukazawa R, Ogawa C, Furuno K, Tokunaga H, Takatsuki S, Hara S, Morikawa A, RAISE Study Group Investigators. Efficacy of immunoglobulin plus prednisolone for prevention of coronary artery abnormalities in severe Kawasaki disease: a prospective, randomised, open, blinded-endpoint trial. The LANCET, 2012, in Press.

・Late delirious behavior with 2009 H1N1 Influenza; mild autoimmune-mediated encephalitis Jun-ichi Takanashi, Yukitoshi Takahashi, Atsushi Imamura, Kazuhiko Kodama, Akimitsu Watanabe, Koji Tominaga, Kazuhiro Muramatsu, A. James Barkovich Pediatrics in Press

・Mizuno T, Sakai H, Nishikomori R, Oshima K, Ohara O, Hata I, Shigematsu Y, Ishige T, Tamura K, Arakawa H. Novel mutations of MVK gene in Japanese family members affected with hyperimmunoglobulinemia D and periodic fever syndrome. Rheumatol Int. 2011 Dec 11. [Epub ahead of print]

・Nakajima N, Mochizuki H, Muramatsu R, Hagiwara S, Mizuno T, Arakawa H. Relationship between exhaled nitric oxide and small airway lung function in normal and asthmatic children. Allergol Int. 60(1):53-59. 2011.

・Oki K, Takita J, Hiwatari M, Nishimura R, Sanada M, Okubo J, Adachi M, Sotomatsu M, Kikuchi A, Igarashi T, Hayashi Y, Ogawa S. IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies. Leukemia 25 : 382-384, 2011

・Seki M, Kobayashi T, Kobayashi T, Morikawa A, Otani T, Takeuchi K, Ayusawa M, Tsuchiya K, Yasuda K, Suzuki T, Shimoyama S, Ikeda K, Ishii Y, Arakawa H. External Validation of a Risk Score to Predict Intravenous Immunoglobulin Resistance in Patients With Kawasaki Disease. Pediatr Infect Dis J. 30(2):145-147. 2011.

・Seki M, Kurishima C, Kawasaki H, Masutani S, Senzaki H. Aortic stiffness and aortic dilation in infants and children with tetralogy of Fallot before corrective surgery: evidence for intrinsically abnormal aortic mechanical property. Eur J Cardiothorac Surg. 2011 Jun 15. [Epub ahead of print]

・Sekine K, Mochizuki H, Inoue Y, Kobayashi T, Suganuma E, Matsuda S, Arakawa H. Regulation of oxidative stress in patients with Kawasaki disease. Inflammation 2011 Oct 20. [Epub ahead of print].

・Shiba N, Taki T, Park MJ, Nagasawa M, Kanazawa T, Takita J, Ohnishi H, Sotomatsu M, Arakawa H, Hayashi Y. CBL mutation in childhood therapy-related leukemia. Leukemia 25 : 1356-1358, 2011

・Shiba N, Taki T, Park MJ, Nagasawa M, Kanazawa T, Takita J, Ohnishi H, Sotomatsu M, Arakawa H, Hayashi Y. CBL mutation in childhood therapy-related leukemia. Leukemia. 25:1356-1358.2011

・Tatsuki M, Miyazawa R, Tomomasa T, Ishige T, Nakazawa T, Arakawa H. Serum magnesium concentration in children with functional constipation treated with magnesium oxide. World J Gastroenterol. 17(6):779-783. 2011.

・Tomomasa T, Tajiri H, Kagimoto S, Shimizu T, Yoden A, Ushijima K, Uchida K, Kaneko H, Abukawa D, Konno M, Maisawa S, Kohsaka T, Kobayashi A;Japanese Study Group for Pediatric Ulcerative Colitis.Leukocytapheresis in pediatric patients with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2011 Jul;53(1):34-9.

・Yamada Y, Nishi A, Ebara Y, Kato M, Yamamoto H, Morita H, Nomura I, Matsumoto K, Hirato J, Hatakeyama SI et al. Eosinophilic gastrointestinal disorders in infants: a Japanese case series. Int Arch Allergy Immunol. 155(Suppl 1): 40-45, 2011.

・Yamada Y, Nishi A, Ebara Y, Kato M, Yamamoto H, Morita H, Nomura I, Matsumoto K, Hirato J, Hatakeyama SI, Suzuki N, Hayashi Y. Eosinophilic gastrointestinal disorders in infants: a Japanese case series. Int Arch Allergy Immunol. 155 Suppl 1 :40-45, 2011

2010

・Fuse S, Kobayashi T, Arakaki Y, Ogawa S, Katoh H, Sakamoto N, Hamaoka K, Saji T. Standard method for ultrasound imaging of coronary artery in children. Pediatr Int. 2010 Dec;52(6):876-82

・Ishige T, Tomomasa T, Takebayashi T, Asakura K, Watanabe M, Suzuki T, Miyazawa R, Arakawa H. Inflammatory Bowel Disease in Children: Epidemiological Analysis of the Nationwide IBD Registry in Japan. J Gastroenterol. 45:911-917. 2010 Ishii Y, Suzuki T, Kobayashi T, Arakawa H. Single coronary artery with right ventricular fistula: Case report and literature review. Congenit Heart Dis. 5;56-59. 2010

・Kobayashi T, Miyamoto T, Kobayashi T, Ikeda K, Koizuka K, Okamoto H, Miyaji K. Staged repair of truncus arteriosus with interrupted aortic arch: adjustable pulmonary artery banding. Ann Thorac Surg. 89;973-975. 2010

・Kondo N, Nishimuta T, Nishima S, Morikawa A, Aihara Y, Akasaka T, Akasawa A, Adachi Y, Arakawa H, Ikarashi T, Ikebe T, Inoue T, Iwata T, Urisu A, Ebisawa M, Ohya Y, Okada K, Odajima H, Katsunuma T, Kameda M, Kurihara K, Kohno Y, Sakamoto T, Shimojo N, Suehiro Y, Tokuyama K, Nambu M, Hamasaki Y, Fujisawa T, Matsui T, Matsubara T, Mayumi M, Mukoyama T, Mochizuki H, Yamaguchi K, Yoshihara S; Japanese Society of Pediatric Allergy and Clinical Immunology. Japanese pediatric guidelines for the treatment and management of bronchial asthma 2008. Pediatr Int. 52(2):319-26. 2010

・Morikawa A. Use of Theophylline and Sodium Cromoglycate in Pediatric Asthma. Allergy Frontiers:Therapy and Prevention. 5:727-735.2010

・Nagai Y, Mizuno T, Yoshizawa C, Ishikawa O. Fatal interstitital pneumonia in juvenile dermatomyositis. Eur J Dermatol 20(2):1-3. 2010

・Nshimuta T,Kondo N,Hmasaki Y,Morikawa A,Nishima S.Japanese guideline for childhood asthma.Allergol Int.2011 Mar,60(2):147-69

・Seki M, Kobayashi T, Kobayashi T, Morikawa A, Otani T, Takeuchi K, Ayusawa M, Tsuchiya K, Yasuda K, Suzuki T, Shimoyama S, Ikeda K, Ishii Y, Arakawa H. External Validation of a Risk Score to Predict Intravenous Immunoglobulin Resistance in Patients With Kawasaki Disease. Pediatr Infect Dis J. 2010 Aug 26.

・Seki M, Kimura H, Mori A, Shimada A, Yamada Y, Maruyama K, Hayashi Y, Agematsu K, Morio T, Yachie A, Kato M. Prominent eosinophilia but less eosinophil activation in a patient with Omenn syndrome. Pediatr Int. 2010 Aug;52(4):e196-9

・Shiba N, Kanazawa T, Park MJ, Okuno H, Tamura K, Tsukada S, Hayashi Y, Arakawa H. NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia. Pediatr Blood Cancer. 2010 Dec 15;55(7):1406-9.

・Shiba N, Kato M, Park MJ, Sanada M, Ito E, Fukushima K, Sako M, Arakawa H, Ogawa S, Hayashi Y.Leukemia. CBL mutations in juvenile myelomonocytic leukemia and pediatric myelodysplastic syndrome. 2010 May;24(5):1090-2. Epub 2010 Apr 1

・Tsuchida M, Ohara A, Manabe A, Kumagai M, Shimada H, Kikuchi A, Mori T, Saito M, Akiyama M, Fukushima T, Koike K, Shiobara M, Ogawa C, Kanazawa T, Noguchi Y, Oota S, Okimoto Y, Yabe H, Kajiwara M, Tomizawa D, Ko K, Sugita K, Kaneko T, Maeda M, Inukai T, Goto H, Takahashi H, Isoyama K, Hayashi Y, Hosoya R, Hanada R; Tokyo Children’s Cancer Study Group. Long-term results of Tokyo Children’s Cancer Study Group trials for childhood acute lymphoblastic leukemia, 1984-1999. Leukemia. 2010 Feb;24(2):383-96. Epub 2009 Dec 24.

2009

・Tadaki H, Arakawa H, Mizuno T, Suzuki T, Takeyama K, Mochizuki H, Tokuyama K, Yokota S, Morikawa A. Double-stranded RNA and TGF-alpha promote MUC5AC induction in respiratory cells. J Immunol. 182(1):293-300. 2009

・Tadaki H, Arakawa H, Sugiyama M, Ozawa K, Mizuno T, Mochizuki H, Morikawa A. Association of cord blood cytokine levels with wheezy infants in the first year of life. Pediatr Allergy Immunol. 20:227-233. 2009

・Mochizuki H, Muramatsu R, Tadaki H, Mizuno T, Arakawa H, Morikawa A. Effects of skin care with shower therapy on children with atopic dermatitis in elementary schools. Pediatr Dermatol. 26(2):223-5. 2009

・Mochizuki H, Tadaki H, Takami S, Muramatsu R, Hagiwara S, Mizuno T, Arakawa H. Evaluation of out-in skin transparency using a colorimeter and food dye in patients with atopic dermatitis. Br J Dermatol. 160(5):972-9. 2009

・Tadaki H, Mochizuki H, Muramastu R, Hagiwara S, Takami S, Mizuno T, Arakawa H. Effect of bronchoconstriction on exhaled nitric oxide levels in healthy and asthmatic children. Ann Allergy Asthma Immunol. 102(6):469-74. 2009

・Mochizuki H, Todokoro M, Arakawa H. RS virus-induced inflammation and the intracellular glutathione redox state in cultured human airway epithelial cells. Inflammation. 32(4):252-64. 2009

・Mochizuki H, Muramatsu R, Hagiwara S, Takami S, Mizuno T, Arakawa H. Relationship between bronchial hyperreactivity and asthma remission during adolescence.Ann Allergy Asthma Immunol. 103(3):201-5. 2009

・Fukami M, Nishimura G, Homma K, Nagai T, Hanaki K, Uematsu A, Ishii T, Numakura C, Sawada H, Nakacho M, Kowase T, Motomura K, Haruna H, Nakamura M, Ohishi A, Adachi M, Tajima T, Hasegawa Y, Hasegawa T, Horikawa R, Fujieda K, Ogata T. Cytochrome P450 Oxidoreductase Deficiency: Identification and Characterization of Biallelic Mutations and Genotype-Phenotype Correlations in 35 Japanese Patients.  J Clin Endocrin Metab. First published ahead of print March 3, 2009 as doi:10.1210/jc.2008-2816

・Cutaneous necrosis induced by extravasation of arginine monohydrochloride.Amano H, Nagai Y, Kowase T, Ishikawa O.Acta Derm Venereol. 2008;88(3):310-1

・Kobayashi T, Miyamoto T, Kobayashi T, Ikeda K, Koizuka K, Okamoto H, Miyaji K. Staged repair of truncus arteriosus with interrupted aortic arch: adjustable pulmonary artery banding. Ann Thorac Surg. 2009, in Press

・Kobayashi T, Inoue Y, Otani T, Morikawa A, Kobayashi T, Takeuchi K, Saji T, Sonobe T, Ogawa S, Miura M, Arakawa H. Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy for Kawasaki disease. Pediatr Infect Dis J. 2009;28:498-502.

・Miyamoto T, Doi Y, Ikeda K, Kobayashi T, Kobayashi T. Repair of narrowed coronary sinus without connecting superior vena cava. Asian Cardiovascular & Thoracic Annals. 2009, 17: 186-188

・Senzaki H, Kumakura R, Ishido H, Masutani S, Seki M, Yoshiba S. Left atrial systolic force in children: reference values for normal children and changes in cardiovascular disease with left ventricular volume overload or pressure overload. J Am Soc Echocardiogr. 2009 Aug;22(8):939-46.

・Masutani S, Seki M, Taketazu M, Senzaki H. Successful management of the persistent pulmonary hypertension of the newborn with transposition of the great arteries by restricted patency of the ductus arteriosus: a simple and rational novel strategy. Pediatr Cardiol. 2009 Oct;30(7):1003-5

・Seki M, Kato T, Masutani S, Matsunaga T, Senzaki H. Pulmonary arterial hypertension associated with gastroesophageal reflux in a 2-month-old boy with down syndrome. Circ J. 2009 Dec;73(12):2352-4.

・Ishii Y, Suzuki T, Kobayashi T, Arakawa. Single coronary artery with right ventricular fistula: Case report and literature review. Congenit Heart Dis. 2010 Jan/Feb, in Press.

・Ishige T., Tomomasa T., Takebayashi T, Asakura K, Watanabe M, Suzuki T, Miyazawa R, Arakawa H, Inflammatory Bowel Disease in Children: Epidemiological Analysis of the Nationwide IBD Registry in Japan. J Gastroenterol (under review)

・Periventricular echodensity measured with the integrated backscatter system: From a qualitative assessment to a quantitative approach. Neonatology 2009;96:219-225

・Ikeuchi Y、Kobayashi Y、Arakawa H、Suzuki M、Tamura K、Morikawa A. Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome.
Pediatr Nephrol. 2009 Mar; 24(3): 489-95

・Arakawa H, Kobayashi Y. Genetics: Childhood Allergy and Epigenetics Inrernational Review of Asthma: Vol.11 No.1: 2009

2008

・Koitabashi M, Kanazawa T, Tamura K, Tsukada S, Suzuki M, Morikawa A, Ogawa C, Hirado J
A novel mutation of the SMARCB1 gene in a case of extrarenal malignant rhabdoid tumor : Letter to the editor. Cancer Genet Cytogenet. 2008:181(1);67-8.

・Suzuki T, Arakawa H, Mizuno T, Muramatsu K, Tadaki H, Takizawa T, Mochizuki H, Tokuyama K, Matsukura S, Morikawa A
Differential Regulation of Eotaxin Expression by Dexamethasone in Normal Human Lung Fibroblasts. Am J Respir Cell Mol Biol. 2008:38(6);707-714.

・Wang J, Mochizuki H, Todokoro M, Arakawa H, Morikawa A
Does leukotriene affect intracellular glutathione redox state in cultured human airway epithelial cells? Antioxid Redox Signal. 2008:10(4);821-8.

・Ishige T, Kaneko H, Suzuki T, Miyazawa R, Tomomasa T, Kubota M, Morikawa A
Pemphigus vulgaris as a possible cause of protein-losing gastroenteropathy: a case report. J Paediatr Child Health. 2008:44(3);143-5.

・Shimoyama S, Kobayashi T, Inoue Y, Mochizuki H, Hamajima A, Kobayashi T, Hatakeyama S, Morikawa A
Left displacement of the mediastinum determines the imbalance in the pulmonary vascular bed and lung volume in children with pectus excavatum. Pediatr Surg Int. 2008:24(5);549-53.

・Muramatsu K, Hashimoto Y, Uemura T, Kunii M, Harada R, Sato T, Morikawa A, Harada A
Neuron-specific recombination by Cre recombinase inserted into the murine tau locus. Biochem Biophys Res Commun. 2008:370(3);419-23.

・Miyazawa R, Tomomasa T, Kaneko H, Arakawa H, Shimizu N, Morikawa A
Effects of pectin liquid on gastroesophageal reflux disease in children with cerebral palsy. BMC Gastroenterol. 2008:8:11.

・Tadaki H, Mochizuki H, Muramastu R, Hagiwara S, Mizuno T, Arakawa H, Morikawa A
A flow- and pressure-controlled offline method of exhaled nitric oxide measurement in children. Ann Allergy Asthma Immunol. 2008:100(4);308-13.

・Tamura K, Kanazawa T, Tsukada S, Kobayashi T, Kawamura M, Morikawa A
Increased serum monocyte chemoattractant protein-1, macrophage inflammatory protein-1beta, and interleukin-8 concentrations in hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2008;51(5):662-8.

・Mizoguchi F, Hiroyuki Mochizuki H, Muramatsu R, Tadaki H, Kobayashi T, Arakawa H, Onigata K, Morikawa A
Relationship between the Serum Leptin Concentration and Bronchial Hyperresponsiveness in Pre-school Children. Pediatric Asthma Allergy and Immunology, 21, 2008.

・Ohki Y, Mayuzumi H, Tokuyama K, Yoshizawa Y, Arakawa H, Mochizuki H, Morikawa A
Hepatocyte Growth Factor Treatment Improves Alveolarization in a Newborn Murine Model of Bronchopulmonary Dysplasia. Neonatology. 2008:22;95(4):332-338.

・Ohki Y, Yoshizawa Y, Watanabe M, Kuwashima M, Morikawa A
Complications of percutaneously inserted central venous catheters in Japanese neonates. Pediatr Int 50; 636-639,2008..

・Suzuki M, Takahashi A, Toki F, Hatori R, Tomomasa T, Morikawa A, Kuwano H
The effects of intestinal ischemia on colonic motility in conscious rats. J Gastroenterol. 2008;43(10):767-73.

・Connor FL, Hyman PE, Faure C, Tomomasa T, Pehlivanov N, Janosky J, Rudolph C, Liem O, di Lorenzo C
Interobserver variability in antroduodenal manometry. Neurogastroenterol Motil. 2008 Jul 29. [Epub ahead of print] (IF:3.364)

・Tajiri H, Tomomasa T, Yoden A, Konno M, Sasaki M, Maisawa S, Sumazaki R, Shimizu T, Toyoda S, Etani Y, Nakacho M, Ushijima K, Kobayashi A; Japanese Society for Pediatric Inflammatory Bowel Disease
Efficacy and safety of azathioprine and 6-mercaptopurine in Japanese pediatric patients with ulcerative colitis: a survey of the Japanese Society for Pediatric Inflammatory Bowel Disease. Digestion. 2008;77(3-4):150-4.

・Kitamura A, Tsukaguchi H, Maruyama K, Shono A, Iijima K, Kagami S, Doi T: Steroid-resistant nephrotic syndrome. Kidney Int. 2008; 74(9): 1209-1215.

・Amano H, Nagai Y, Kowase T, Ishikawa O
Cutaneous necrosis induced by extravasation of arginine monohydrochloride. Acta Derm Venereol. 2008;88(3):310-1. No abstract available.

・Hashimoto Y, Muramatsu K, Uemura T, Harada R, Sato T, Okamoto K, Harada A
Neuron-specific and inducible recombination by Cre recombinase in the mouse.
Neuroreport 19(6), 621-624 (2008)

・Morita Y, Kogure H, Sandoh M, Kawashima G, Sato Y, Nanba S, Shoda Y, Suzuki T, Shiono M, Shiobara M, Kato M, Kozawa K, Noda M, Okabe N, Kimura H
An imported dengue fever case by dengue virus 3 (DENV-3) infection in Gunma, Japan. Jpn J Infect Dis 61:90-92, 2008.

・Okazaki K, Kondo M, Kato M, Kakinuma R, Nishida A, Noda M, Kimura H
Elevation of High-Mobility Group Box 1 Concentration in Asphyxiated Neonates. Neonatology 94: 105-109, 2008.

・Iijima A, Sato K, Yano K, Kato M, Kozawa K, Furuta N
Emission factor for antimony in brake abrasion dusts as one of the major atmospheric antimony sources. Environ Sci Technol 42: 2937-2942, 2008.

・Okazaki K, Kondo M, Kato M, Kakinuma R, Nishida A, Noda M, Taniguchi K, Kimura H
Serum cytokines/chemokines profiles in neonates with meconium aspiration syndrome. Pediatrics 121: e748-753, 2008.

・Yamaguchi T, Kimura H, Kurabayashi M, Kozawa K, Kato M
Interferon- enhances human eosinophil effector functions induced by granulocyte-macrophage colony-stimulating factor or interleukin-5. Immunol Lett 118: 88-95, 2008.

・Nakazato Y, Tanaka R, Seki E, Iijima M, Kojima M, Yoshizumi M, Kato M, Kimura H, Kozawa K, Goya T
Differential diagnosis of primary versus metastatic pulmonary adenocarcinomas using gene mutation analyses: a case report. J Thorac Oncol 3: 931-934, 2008.

・Iijima A, Tago H, Kumagai K, Kato M, Kozawa K, Sato K, Furuta N
Regional and seasonal characteristics of emission sources of fine airborne particulate matter collected in the center and suburbs of Tokyo, Japan as determined by multielement analysis and source receptor models. J Environ Monit 10: 1025-1032, 2008.

・Mukai H, Hokari Y, Seki T, Takao T, Kubota M, Matsuo Y, Tsukagoshi H, Kato M, Kimura H, Shimonishi Y, Kiso Y, Nishi Y, Wakamatsu K, Munekata E
Discovery of mitocryptide-1, a neutrophil-activating cryptide from healthy porcine heart. J Biol Chem 283: 30596-30605, 2008.

・Yoshizumi M, Nakamura T, Kato M, Ishioka T, Kozawa K, Wakamatsu K, Kimura H
Release of cytokines/chemokines and cell death in UVB-irradiated human keratinocytes, HaCaT. Cell Biol Int 32: 1405-1411. 2008.

・Okazaki K, Kondo M, Kato M, Nishida A, Takahashi H, Noda M, Kimura H
Temporal alterations in concentrations of sera cytokines/chemokines in sepsis due to group B streptococcus infection in a neonate. Jpn J Infect Dis 61: 382-385, 2008.

・Shimada A, Kato M, Tamura K, Hirato J, Kanegane H, Takechi Y, Park M, Sotomatsu M, Hatakeyama S, Hayashi Y
Hemophagocytic lymphohistiocytosis associated with uncontrolled inflammatory cytokinemia and cytokinemia was caused by systemic anaplastic large cell lymphoma: a case report and review of the literature. J Pediatr Hematol Oncol 30: 785-787, 2008.

・K Mauryama
Different clinical manifestation of HCMV in preterm twins: Methodological approach: Reply. Pediatrics International 50: 142, 2008

・Miyazawa R, Tomomasa T, Kaneko H, Arakawa H, Shimizu N, Morikawa A. Effects of pectin liquid on gastroesophageal reflux disease in children with cerebral palsy. BMC Gastroenterol. 2008 Apr 16;8:11.

・Suzuki M, Takahashi A, Toki F, Hatori R, Tomomasa T, Morikawa A, Kuwano H. The effects of intestinal ischemia on colonic motility in conscious rats. J Gastroenterol. 2008;43(10):767-73. Epub 2008 Oct 29.

・Tajiri H, Tomomasa T, Yoden A, Konno M, Sasaki M, Maisawa S, Sumazaki R, Shimizu T, Toyoda S, Etani Y, Nakacho M, Ushijima K, Kobayashi A. Japanese Society for Pediatric Inflammatory Bowel Disease
Efficacy and safety of azathioprine and 6-mercaptopurine in Japanese pediatric patients with ulcerative colitis: a survey of the Japanese Society for Pediatric Inflammatory Bowel Disease. Digestion. 2008;77(3-4):150-4. Epub 2008 Jun 24.

・Kato M, Tsukagoshi H, Yoshizumi M, Saitoh M, Kozawa K, Yamada Y, Maruyama K, Hayashi Y, Kimura H. Rhinovirus enhances eosinophil activation through the production of IL-5 in acute exacerbation of childhood asthma. (65th Annual meeting of American Allergy, Asthma and Immunology, March 17,2009, Washington, DC, USA.)

・Kato M, Tsukagoshi H, Yoshizumi M, Saitoh M, Kozawa K, Yamada Y, Maruyama K, Hayashi Y, Kimura H. Rhinovirus enhances eosinophil activation through the production of IL-5 in acute exacerbation of childhood asthma. (65th Annual meeting of American Allergy, Asthma and Immunology, March 17, 2009, Washington, DC, USA.)

・Morikawa A. The asthma treatment, management and education in Japan. (Asia Pacific Association of Pedeiatric Allergy, Respirology & Immunology, Apr 18, 2009, China.)

・Morikawa A. Food Allergy in Japan. (Pediatric Academic Societies & Asian Society for Pediatric Research Joint Meeting, May 3-5,2008, Hawaii, USA.)

・Morikawa A. Asthma Guideline and Asthma mortality in JAPAN. (The 2008 APAPARI meeting in conjunction with the Annual Singapore Paediatric Congress, Oct 4, 2008, Singapore.)

・Tomio Kobayashi, Tohru Kobayashi, Makoto Shinohara, Katsuhiko Sone, Kentaro Ikeda, Takahiro Suzuki, Shinya Shimoyama, Mitsuru Seki, Yasunori Okada. Adverse effects from corticosteroids therapy for acte phase Kawasaki disease. 9th International Kawasaki Disease Symposium. Taipei, Taiwan, 12 April, 2008.

・Tohru Kobayashi, Yoshinari Inoue, Kazuo Takeuchi, Yasunori Okada, Tomio Kobayashi, Kazushi Tamura, Takeshi Tomomasa, and Akihiro Morikawa. A simple risk score to predict intravenous immunoglobulin non-responders in patients with Kawasaki disease. 9th International Kawasaki Disease Symposium. Taipei, Taiwan, 11 April, 2008.

・Tohru Kobayashi, Yoshinari Inoue, Tetsuya Otani, Tomio Kobayashi, Kazuo Takeuchi, Tsutomu Saji, Tomoyoshi Sonobe, Shunichi Ogawa, Masaru Miura, Mitsuru Seki, Kentaro Ikeda, Yoichiro Ishii, Takahiro Suzuki, Shinya Shimoyama, Akihiro Morikawa. Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease. Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

・Takahiro Suzuki, Tohru Kobayashi, Yoshinari Inoue, Tetsuya Otani, Tomio Kobayashi, Kazuo Takeuchi, Mitsuru Seki, Kentaro Ikeda, Yoichiro Ishii, Shinya Shimoyama, Morikawa Akihiro. Risk stratification in the decision to include prednisolone with intravenous immunoglobulin in primary therapy of Kawasaki disease. 9th International Kawasaki Disease Symposium. Taipei, Taiwan, 12 April, 2008.

・Shinya Shimoyama, Tohru Kobayashi, Yoshinari Inoue, Kazuo Takeuchi, Tomio Kobayashi, Yasunori Okada, Kazushi Tamura, Takeshi Tomomasa, Tetuya Otani, Hirokazu Arakawa and Akihiro Morikawa. A new scoring system to predict intravenous immunoglobulin unresponsiveness in patients with Kawasaki disease. 14th World Congress on Heart Disease, The International Academy of Cardiology Annual Scientific Sessions 2008 Toronto, Canada, 28 July, 2008.

・Kentaro Ikeda, Tohru Kobayashi, Yoichiro Ishii, Tomio Kobayashi. Percutaneous hydrodynamic thrombectomy for congenital deep vein thrombosis in a neonate;21st European Congress of Perinatal Medicine 2008.9.13. Isutanbul, Turkey

・Mitsuru Seki, Tohru Kobayashi, Yoshinari Inoue, Mamoru Ayusawa, Takahiro Nakamura, Tomio Kobayashi, Kentaro Ikeda, Yoichiro Ishii, Takahiro Suzuki, Shinya Shimoyama and Akihiro Morikawa. External Validation Of A Risk Score To Predict Intravenous Immunoglobulin Unresponsiveness In Patients With Kawasaki Disease, Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

・Kazuhiro Muramatsu , Takashi Sato , Akihiro Morikawa and Akihiro Harada,Tau-Cre Knock-In Mice Mediate Highly Efficient and Specific Recombination by Cre Recombination in Neuron.ASPR( Asian Society for Pediatric Research)2008 Annual Meeting in Honolulu, Hawaii, May 3-6.JSPN Award for Excellence

・Takashi Ishige, Takeshi Tomomasa, Tomoko Suzuki, Reiko Miyazawa, Tohru Takebayashi, Keiko Asakura, Akihiro Morikawa. Growth in Pediatric Onset Inflammatory Bowel Disease Analysis Using the Japanese Nationwide IBD Registry Database. Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

・Maiko Ono, Reiko Miyazawa, Takeshi Tomomasa, Akihiro Morikawa. Defecation Frequency and Stool Consistency in Healthy Infants. Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

・Reiko Miyazawa, Takeshi Tomomasa, Takashi Ishige, Hirokazu Arakawa, Akihiro Morikawa. Effect of Hypoxia on Gastrointestinal Motility and Gastric Emptying in Conscious Rat. Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

・Tomoko Suzuki, Hirokazu Arakawa, Hiromi Tadaki, Takahisa Mizuno, Hiroyuki Mochizuki, Akihiro Morikawa. Differential Regulation of Eotaxin Expression by Dexamethasone in Normal Human Lung Fibroblasts. Pediatric Academic Society 2008, Honolulu, Hawaii, USA, 4 May, 2008

2007

・Kobayashi T, Kimura H, Okada Y, Inoue Y, Kobayashi T, Shinohara M, Morikawa A. Increased CD11b expression on polymorphonuclear leucocytes and cytokine profiles in patients with Kawasaki disease. Clin Exp Immunol. 148:112-118,2007.

・Sugiyama M, Arakawa H, Ozawa K, Mizuno T, Mochizuki H, Tokuyama K, Morikawa A. Early-life risk factors for occurrence of atopic dermatitis during the first year. Pediatrics. 119(3):716-23. 2007

・Mayuzumi H, Ohki Y, Tokuyama K, Sato A, Mizuno T, Arakawa H, Mochizuki H, Morikawa A. Age-Related Difference in the Persistency of Allergic Airway Inflammation and Bronchial Hyperresponsiveness in a Murine Model of Asthma. Int Arch Allergy Immunol.143(4):255-262. 2007

・Shiba N, Tamura K, Kanazawa T, Tsukada S, Koitabashi M, Morikawa A. Novel three-way t(4;5;22)(q35;q31;q13) in acute megakaryoblastic leukemia. Cancer Genet Cytogenet. 174(1):82-3. 2007

・Kobayashi T, Inoue Y, Tamura K, Morikawa A, Kobayashi T. External validation of a scoring system to predict resistance to intravenous immunoglobulin. J Pediatr. 150(4):e37. 2007

・Miyazawa R, Tomomasa T, Kaneko H, Arakawa H, Morikawa A. Effect of formula thickened with reduced concentration of locust bean gum on gastroesophageal reflux. Acta Paediatr. 96(6):910-4. 2007

・Kobayashi K, Katsuya Y, Abdulah R, Fujisawa C, Nagamine T, Morikawa A, Murakami M, Kodama H, Koyama H. Direct Analysis of Ceruloplasmin in Human Blood Serum by HPLC/Inductively Coupled Plasma-Mass Spectrometry for the Diagnosis of Wilson Disease. Biomedical Research on Trace Elements. 18(1):91-95. 2007

・Watanabe M, Ohki Y, Yoshizawa Y, Inoue Y, Tokuyama K, Morikawa A. Maturational Changes in Skin Color of Japanese Newborn Infants. Neonatology. 91:275-280. 2007

・Inoue Y, Kobayashi T, Morikawa A. Treatment of Kawasaki disease.N Engl J Med. 356(26):2746-7; author reply 2748. 2007″

・Shimizu Y, Dobashi K, Hisada T, Ono A, Todokoro M, Iiima H, Utugi M, Kakegawa S, Iizuka K, Ishizuka T, Morikawa A, Mori M. Acute impact of volcanic ash in asthma symptoms and treatment. International Journal of Immunopathology and Pharmacology. 20(2)(S2):9-14. 2007

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of nasopharyngeal bacterial flora. Variations in nasopharyngeal bacterial flora in schoolchildren and adults when administered antimicrobial agents.
J Infect Chemother. 13(4):235-54. 2007″

・Mukoyama T, Nishima S, Arita M, Ito S, Urisu A, Ebisawa M, Ogura H, Kohno Y, Kondo N, Shibata R, Hurusho M, Mayumi M, Morikawa A and Food Allergy Committee, Japanese Society of Pediatric Allergy and Clinical Immunology
Guidelines for diagnosis and management of pediatric food allergy in Japan.Allergol Int. 2007;56(4):349-61. 2007

・Morikawa A, Nishima S. THE JAPANESE SOCIETY OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY. New Japanese pediatric guidelines for the treatment and management of bronchial asthma.Pediatr Int. 49(6):1023-1031. 2007

・Tahakashi A, Hasegawa M, Sumazaki R, Suzuki M, Toki F, Suehiro T, Onigata K, Tomomasa T, Suzuki T, Matsui A, Morikawa A, Kuwano H. Gradual improvement of liver function after administration of uresodeoxycholic acid in an infant with a novel ABCB11 gene mutation with phenotypic continuum between BRIC2 and PFIC2. European Journal of Gastroenterology & Hepatology. 19(11):942-946. 2007

・Saotome C, Mochizuki H, Kobayashi T, Arakawa H, Tokuyama K, Koyama H, Morikawa A. Effect of medical treatments on an improvement of asthma in the early stage of life. Pediatric Asthma, Allergy & Immunology. 20:83-92.2007

2006

・Saitoh M, Shinkawa N, Shimada S, Segawa Y, Sadamasu K, Hasegawa M, Kato M, Kozawa K, Kuramoto T, Nishio O, Kimura H. Phylogenetic analysis of envelope glycoprotein (E1) gene of rubella viruses prevalent in Japan in 2004. Microbiol Immunol.50(3):179-85. 2006

・Roy BB, Jinno-Oue A, Shinagawa M, Shimizu A, Tamura K, Shimizu N, Tanaka A, Hoshino H. Isolation of the feline alpha1,3-galactosyltransferase gene, expression in transfected human cells and its phylogenetic analysis. Exp Zoolog B Mol Dev Evol.306(1):59-69. 2006

・Tamura K, Kanazawa T, Suzuki M, Shioya A, Morikawa A. Successful induction of immune tolerance by continuous infusion of recombinant factor VIII in a haemophilia A patient with high-inhibitor titres. Haemophilia. 12(1):100-2. 2006

・Takagi H, Hagiwara S, Hashizume H, Kanda D, Sato K, Sohara N, Kakizaki S, Takahashi H, Mori M, Kaneko H, Ohwada S, Ushikai M, Kobayashi K, Saheki T. Adult onset type II citrullinemia as a cause of non-alcoholic steatohepatitis. J Hepatol.44(1):236-9 .2006

・Kobayashi T, Kobayashi T, Mayuzumi H, Morikawa A. Percutaneous hydrodynamic thrombectomy for congenital deep vein thrombosis in a neonate. Pediatr Cardiol. 27(1):170-4. 2006

・Mochizuki H, Arakawa H, Tokuyama K, Morikawa A. Effect of age on bronchial reactivity in children with asthma. J Asthma. 43(1):25-9. 2006

・Tamura K, Kanazawa T, Suzuki M, Koitabashi M, Ogawa C, Morikawa A. Successful rapid discontinuation of immunosuppressive therapy at molecular relapse after allogeneic bone marrow transplantation in a pediatric patient with myelodysplastic syndrome. Am J Hematol. 81(2):139-41. 2006

・Kitanaka S, Sato U, Maruyama K, Igarashi T. A compound heterozygous mutation in the BSND gene detected in Bartter syndrome type IV. Pediatr Nephrol.21(2):190-3. (2006)

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of upper respiratory tract bacterial flora: first report. Variations in upper respiratory tract bacterial flora in patients with acute upper respiratory tract infection and healthy subjects and variations by subject age. J Infect Chemother;12(2):83-96. 2006

・Foronjy RF, Mirochnitchenko O, Propokenko O, Lemaitre V, Jia Y, Inouye M, Okada Y, D’Armiento JM. Superoxide dismutase expression attenuates cigarette smoke- or elastase-generated emphysema in mice. Am J Respir Crit Care Med. 173(6):623-31. 2006

・Muramatsu R, Mochizuki H, Arakawa H, Tokuyama K, Morikawa A. Effect of inhaled histamine on airway epithelial cell swelling in ozone-exposed Guinea pigs. Respiration.73(5):673-9. 2006

・Wang J, Mochizuki H, Muramatsu R, Arakawa H, Tokuyama K, Morikawa A. Evaluation of bronchial hyperresponsiveness by monitoring of transcutaneous oxygen tension and arterial oxygen saturation during methacholine challenge in asthmatic children. J Asthma. 43(2):145-9. 2006

・Okazaki K, Nishida A, Kato M, Kozawa K, Uga N, Kimura H. Elevation of cytokine concentrations in asphyxiated neonates. Biol Neonate. 89(3):183-9. 2006

・Tsunekawa K, Onigata K, Morimura T, Kasahara T, Nishiyama S, Kamoda T, Mori M, Morikawa A, Murakami M. Identification and functional analysis of novel inactivating thyrotropin receptor mutations in patients with thyrotropin resistance. Thyroid. 16(5):471-9. 2006

・Kimura H, Yoshizumi M, Iijima M, Tsukagoshi T, Nishimura T, Kato M, Morita Y, Tanaka R, Kozawa K, Fujita M, Kojima M, Minakami H. Tuberculosis-like peritonitis due to an atypical Mycobacterium infection in a Japanese woman. Jpn J Infect Dis. 59(3):189-91. 2006

・Kobayashi T, Inoue Y, Takeuchi K, Okada Y, Tamura K, Tomomasa T, Kobayashi T, Morikawa A. Prediction of intravenous immunoglobulin unresponsiveness in patients with Kawasaki disease. Circulation. 113(22):2606-12. 2006

・Kato M, Kimura H, Seki M, Shimada A, Hayashi Y, Morio T, Kumaki S, Ishida Y, Kamachi Y, Yachie A. Omenn syndrome–review of several phenotypes of Omenn syndrome and RAG1/RAG2 mutations in Japan. Allergol Int.55(2):115-9. 2006

・Working Group of the Japanese Society for Pediatric Gastroenterology, Hepatology and Nutrition; Konno M, Kobayashi A, Tomomasa T, Kaneko H, Toyoda S, Nakazato Y, Nezu R, Maisawa S, Miki K. Guidelines for the treatment of Crohn’s disease in children. Pediatr Int. 48(3):349-52. 2006

・Muto Y, Sato S, Watanabe A, Moriwaki H, Suzuki K, Kato A, Kato M, Nakamura T, Higuchi K, Nishiguchi S, Kumada H, Ohashi Y; for the Long-Term Survival Study (LOTUS) Group. Overweight and obesity increase the risk for liver cancer in patients with liver cirrhosis and long-term oral supplementation with branched-chain amino acid granules inhibits liver carcinogenesis in heavier patients with liver cirrhosis. Hepatol Res. 35(3):204-14. 2006

・Inoue Y, Okada Y, Shinohara M, Kobayashi T, Kobayashi T, Tomomasa T, Takeuchi K, Morikawa A. A multicenter prospective randomized trial of corticosteroids in primary therapy for Kawasaki disease: clinical course and coronary artery outcome. J Pediatr. 149(3):336-341. 2006

・Yamaguchi T, Suzuki M, Kimura H, Kato M. Role of protein kinase C in eosinophil function. Allergol Int. 55(3):245-52. 2006

・Kondo N, Katsunuma T, Odajima Y, Morikawa A. A randomized open-label comparative study of montelukast versus theophylline added to inhaled corticosteroid in asthmatic children. Allergol Int. 55(3):287-93. 2006

・Wang J, Mochizuki H, Muramatsu R, Mizuno T, Arakawa H, Tokuyama K, Morikawa A. Effect of Aging on the Relationship between Asthma Severity and Bronchial Hyperresponsiveness in Children with Asthma. J Asthma. 43(8):607-12. 2006

・Adachi M, Ohta K, Morikawa A, Nishima S. [Asthma Insights & Reality in Japan 2005] Arerugi.55(10):1340-3. 2006

・Konno M, Baba S, Mikawa H, Hara K, Matsumoto F, Kaga K, Nishimura T, Kobayashi T, Furuya N, Moriyama H, Okamoto Y, Furukawa M, Yamanaka N, Matsushima T, Yoshizawa Y, Kohno S, Kobayashi K, Morikawa A, Koizumi S, Sunakawa K, Inoue M, Ubukata K. Study of nasopharyngeal bacterial flora. Second report. Variations in nasopharyngeal bacterial flora in children aged 6 years or younger when administered antimicrobial agents. Part 2. J Infect Chemother. ;12(5):305-30. 2006

・Miyazawa R, Tomomasa T, Kaneko H, Morikawa A. Effect of formula thickened with locust bean gum on gastric emptying in infants. J Paediatr Child Health. 42(12):808-12. 2006

・Kobayashi Y, Watanabe T, Inoue Y, Arakawa H, Mochizuki H, Tokuyama K, Morikawa A. CR8/194-A case of fulminated fatal disseminated Varicella Zoster virus infection with severe pulmonary damage. Paediatr Respir Rev.7S:S328. 2006

・Morikawa A. Asthma : What We learn from each other’s prpblems? The present state of asthma in Japan and Japanese Pediatric Guidelines for the Treatment and Management of Asthma(JPGTMA). Paediatric Respiratory Reviews.7S:S121-S122. 2006

・Tamura K. Detection of minimal residual disease : Clinical utility in myelodysplastic syndrome in children. Res. Adv. In Hematology 1:1-12. 2006

・Kanda K, Mizuno H, Sugiyama Y, Imamine H, Togari H, Onigata K. Clinical Significance of Heterozygous Carries Associated with Compensated Hypothyroidism in R450H, a Common Inactivating Mutation of the Thyrotropin Receptor Gene in Japanese. Endocrine 30:383-388. 2006

2005

・Tamura K, Oue A, Tanaka A, Shimizu N, Takagi H, Kato N, Morikawa A, Hoshino H. Efficient formation of vesicular stomatitis virus pseudotypes bearing the native forms of hepatitis C virus envelope proteins detected after sonication. Microbes Infect. 7(1):29-40. (2005)

・Kato M, Yamaguchi T, Tachibana A, Kimura H. Differential role of an atypical protein kinase C, PKC zeta, in regulation of human eosinophil and neutrophil functions. Int Arch Allergy Immunol. 137 Suppl 27-34. (2005)

・Kato M, Hayashi Y, Kimura H. Oxygen radicals in inflammation and allergy related to viral infections. Curr Drug Targets Inflamm Allergy. 4(4):497-501. (2005)

・Ohki Y, Tokuyama K, Mayuzumi H, Sato A, Koyama H, Takizawa T, Arakawa H,Mochizuki H, Morikawa A. Characteristic features of allergic airway inflammation in a murine model of infantile asthma. Int Arch Allergy Immunol. 138(1):51-8.9. (2005)

・Arakawa H, Yuhara Y, Todokoro M, Kato M, Mochizuki H, Tokuyama K, Kunimoto F, Morikawa A. Immunoadsorption therapy for a child with Guillain-Barre syndrome subsequent to Mycoplasma infection: a case study. Brain Dev. 27(6):431-3. (2005)

・Kato M, Yamaguchi T, Tachibana A, Suzuki M, Izumi T, Maruyama K, Hayashi Y,Kimura H. An atypical protein kinase C, PKC zeta, regulates human eosinophil effector functions. Immunology. 116(2):193-202. (2005)

・Shiojima T, Fujiki Y, Sagai H, Iyobe S, Morikawa A. Prevalence of Streptococcus pneumoniae isolates bearing macrolide resistance genes in association with integrase genes of conjugative transposons in Japan. Clin Microbiol Infect. 11(10):808-13. (2005)

・Kanazawa T,Ogawa C,Taketani T,Taki T,Hayashi Y,Morikawa A. TLS/FUS-ERG fusion gene in acute lymphoblastic leukemia with t(16;21)(p11;q22) and monitoring of minimal residual disease. Leuk Lymphoma46(12):1833-5 (2005)

・Nishima S,Furusho K,Morikawa A,Mochizuki H,Akasaka T,Sugimoto H,Ikebe T,Nisimuta T,Sekine K,Yamada M,Odajima H,Motomura C,Yamatodani A. Pranlukast Inhibits Exercise-Induced Bronchospasm in Asthmatic Children:A Randomized,Multicenter,Double-Blind,Placebo-Controlled Two-Period Crossover Trial. Pediatric asthma,Allergy&Immunology18(1):5-11(2005)

・Ishii Y,Takizawa T,Arakawa H,Saga R,Mochizuki H,Tokuyama K,Morikawa A. Hemorrhagic bullous lesions in Henoch-Schonlein purpura. Pediatr Int.47(6):694-7(2005)

・Takahashi A,Tomomasa T,Kaneko H,Hatori R,Ishige T,Suzuki M,Mochiki E,Morikawa A,Kuwano H. In vivo recording of colonic motility in conscious rats with deficiency of interstitial cells of Cajal,with special reference to the effects of nitric interstitial cells of Cajal,with special reference to the effects of nitric oxide on colonic motility. J Gastroenterol.40(11):1043-8(2005)

・Mochizuki H,Arakawa H,Tokuyama K,Morikawa A. Bronchial sensitivity and bronchial reactivity in children with cough variant asthma. Chest.128(4):2427-34(2005)

・Koyama H,Tokuyama K,Nishimura H,Mizuno T,Mayuzumi H,Ohki Y,Arakawa H,Mochizuki H,Morikawa A. Effect of disodium cromoglycate on airway mucus secretion during antigen-induced late asthmatic responses in a murine model of asthma. Int Arch Allergy Immunol.138(3):189-96. (2005)

・Inoue Y,Mastuwaki Y,Shin SH,Ponikau JU.,Kita H Nonpathogenic,Environmental Fungi Induce Activation and Degranulation of Human Eosinophils. The Journal of Immunology175(8):5439-5447(2005)

・Tomizawa D,Aoki Y,Nagasawa M,Morio T,Kajiwara M,Sekine T,Shimizu N,Kato M,YachieA,Mizutani S. Novel adopted immunotherapy for mixde chimerism after unrelated cord blood transplantation in Omenn syndrome. Eur J Haematol75(5):441-444(2005)

・Wada T,Toma T,Okamoto H,Kasahara Y,Koizumi S,Agematsu K,Kimura H,Shimada A,Hayashi Y,Kato M,Yachie A. Oligoclonal Expansion of T lymphocytes with multiple second-site mutations leads to Omenn syndrome in a patient with RAG1-deficient severe combined immunodeficiency. Blood106(6):2099-2101(2005)

・Hussain S,Miyazawa R,Tomomasa T,Kaneko H,Takahashi A,Watanabe T,Arakawa H,Morikawa A. Possible involvement of adrenomedullin in lipopolysaccharide-induced small-intestinal motility changes in conscious rats. J Gastroenterol 40:1123-1129(2005)

・Kimura H,Sawada T,Oshima S,Kozawa K,Ishioka T,Kato M. Toxicity and Roles of Reactive Oxygen Species. Current Drug Tagets-Inflammation&Allergy 4:489-495(2005)

2004

・Kaneko H, Tomomasa T, Kubota Y, Todokoro M, Kato M, Miyazawa R, Suzuki T, Hatori Y, Kunimoto F, Yamamoto K, Morikawa A. Pharmacobezoar complicating treatment with sodium alginate. J Gastroenterol. 39(1):69-71. (2004)

・Watanabe M, Ono S, Okada Y, Inoue Y, Kobayashi T, Suzuki T, Sugiyama Y, Ishihara S, Morikawa A. Spontaneous closure of an unroofed coronary sinus. Pediatr Int. 46(6):722-5. (2004)

・Arakawa H,Morikawa A. The genetics of pollinosis. Clin Exp Allergy Revi 4:3-7 (2004)

・Fujiu T,Maruyama K,Koizumi T. Oral iron supplementation in preterm infants treated with erythropoietin. Pediatr Int 46:635-9(2004)

・Kato M,Kimura H. Respiratory syncytial virus induces inflammation in bronchial asthma;Role of eosinophils. Allergology Int 53:301-307 (2004)

・Suzuki M,Arakawa H,Kobayashi Y,Tamura K,Mochizuki H,Tokuyama K,Tamari M,Mao XQ,Shirakawa T,Izuhara K,Morikawa A. Signal Transducers and Activators of Transcription 6 (Stat6) Variants in childhood and adult asthma. Allergology Int 53:241-244(2004)

・Suzuki M,Arakawa H,Tamura K,Takizawa T,Mochizuki H,Tokuyama K,Tamari M,Mao XQ,Shirakawa T,Morikawa A. Dinucleotide reteat polymorphisms in the Signal transducers and activators of transcription 6 (Stat6) gene in allergic diseases. Allergology Int 53:235-240 (2004)

・Watanabe T, Tomomasa T, Kaneko H, Takahashi A, Hussain S, Morikawa A. Effect of endotoxin on colonic motilitiy in conscious rats. Kitakanto Med J 54(2):143-146 (2004)

・Kaneko H,Tomomasa T,Kubota Y,Todokoro M,Kato M,Miyazawa R,Suzuki T,Hatori Y,Kunimoto F,Yamamoto K,Morikawa A. Pharmacobezoar complicating treatment with sodium alginate. J Gastroenterol 39(1):69-71 (2004)

・Shinohara M,Shitara T,Hatakeyama S,Suzuki N,Maruyama K,Kobayashi T,Tsuchida Y. An infant with systemic hypertension,renal artery stenosis,and neruoblastoma. J Pediatr Surg 39(1):103-106 (2004)

・Hikima A, Mochizuki H, Oriuchi N, Endo K, Morikawa A. Semiquantitative analysis of interictal glucose metabolism between generalized epilepsy and localization related epilepsy. Ann Nucl Med. 18(7):579-84. (2004)

・Okada Y, Minakami H, Tomomasa T, Kato M, Inoue Y, Kozawa K, Kimura H, Morikawa A. Serum procalcitonin concentration in patients with Kawasaki disease. J Infect. 48(2):199-205. (2004)

・Todokoro M,Mochizuki H,Tokuyama K,Utsugi M,Dobashi K,Mori M,Morikawa A. Effect of ozone exposure on intracellular glutathione redox state in cultured human airway epithelial cells. Inflammation. 28(2):105-14. (2004)

・Ishii S, Yamada M, Satoh T, Monden T, Hashimoto K, Shibusawa N, Onigata K, Morikawa A, Mori M. Aberrant dynamics of histone deacetylation at the thyrotropin-releasing hormone gene in resistance to thyroid hormone. Mol Endocrinol. 18(7):1708-20. (2004)

・Takahashi A, Ogawa C, Kanazawa T, Watanabe H, Suzuki M, Suzuki N, Tsuchida Y, Morikawa A, Kuwano H. Remission induced by interferon alfa in a patient with massive osteolysis and extension of lymph-hemangiomatosis: a severe case of Gorham-Stout syndrome. J Pediatr Surg. 2005 40(3):E47-50. (2004)

・Miyazawa R,Tomomasa T,Kaneko H,Morikawa A. Effect of locust bean gum in anti-regurgitant milk on the regurgitation in uncomplicated gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 38(5):479-83. (2004)

・Kato M, Kita H, Tachibana A, Hayashi Y, Tsuchida Y, Kimura H. Dual signaling and effector pathways mediate human eosinophil activation by platelet-activating factor. Int Arch Allergy Immunol. 134 Suppl 37-43. Review. (2004)

・Takahashi A, Tomomasa T, Suzuki N, Kuroiwa M, Mochiki E, Tsuchida Y, Morikawa A, Kuwano H. Gastrointestinal manometric findings in a patient with total intestinal aganglionosis. J Pediatr Surg. 39(7):1104-6.

・Nako Y, Tomomasa T, Morikawa A. Risk of hypervitaminosis D from prolonged feeding of high vitamin D premature infant formula. Pediatr Int. 46(4):439-43. (2004)

・Tomomasa T, Kobayashi A, Ushijima K, Uchida K, Kagimoto S, Shimizu T, Tajiri H, Tahara T, Yoden A. Working Group of the Japanese Society for Pediatric, Gastroenterology,Hepatology and Nutrition. Guidelines for treatment of ulcerative colitis in children. Pediatr Int. 46(4):494-6 (2004).

・Morita Y, Maruyama S, Kabeya H, Nagai A, Kozawa K, Kato M, Nakajima T, Mikami T, Katsube Y, Kimura H. Genetic diversity of the dnaJ gene in the Mycobacterium avium complex. J Med Microbiol. 53(Pt 8):813-7. (2004)

2003

・Kimura H, Kato M, Ikeda M, Nagai A, Okada Y, Naito S, Oshima S, Taniguchi K, Kozawa K, Morikawa A. Sulfonated human immunoglobulin enhances CD16-linked CD11b expression on human neutrophils. Cell Biol Int. 27(11):913-9. (2003)

・Kimura H,Saitoh M,Miyakubo H,Yoshida H,Kato M,Nagai A,Kozawa K. Keratoconjunctivitis caused by echovirus type 13 in Japanese children. Pediatr Infect Dis J 22:758-759 (2003)

・Maruyama K,Shiojima T,Koizumi T. Sonographic detection of a malpositioned feeding tube causing esophageal perforation in a neonate. J Clin Ultrasound 31:108-10 (2003)

・Miyazawa R,Arakawa H,Tabata M,Tomomasa T,Okamoto M,Yoshizawa Y,Suzuki T,Ohki Y,Nishimura H,Kuwashima M,Takeuchi H,Morikawa A. Characterization of the Japanese scoring system for bronchial asthma in children. Kitakanto Med J 53(2):179-184 (2003)

・Morita Y,Kimura H,Nagata M,Tsuchiya H,Kato M,Kozawa K,Maruyama S. Cutaneous infection in a cat caused by Mycobacterium avium complex serovar 6. Vet Rec 152:120 (2003)

・Mochizuki M,Amemiya S,Kobayashi K,Kobayasi K,Shimura Y,Ishihara T,Nakagomi Y,Onigata K,Tamai S,Kasuga A,Nanazawa S. Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. Diabetes Care 26:843-847 (2003)

・Nako Y,Tachibana A,Fujiu T,Tomomasa T,Morikawa A. Neonatal thrombocytosis resulting from the maternal use of non-narcotic anti-schizophrenic drugs during pregnancy. Review Series,Psychiatry 1:7-9 (2003)

・Nishida T,Kimura H,Saitoh M,Shinohara M,Kato M,Fukuda S,Munemura T,Mikami T,Kawamoto A,Akiyama M,Kato Y,Nishi K,Kozawa K,Nishio O. Detection,quantitation,and phylogenetic analysis of noroviruses in Japanese oysters. Appl Environ Microbiol. 69(10):5782-6. (2003)

・Takizawa T,Ochiai W,Nakashima K,Taga T. Enhanced gene activation by Notch and BMP signaling cross-talk. Nucleic Acids Res 31(19):5723-31 (2003)

・Kobayashi T, Kobayashi T, Shinohara M, Tomomasa T, Morikawa A. Percutaneous hydrodynamic thrombectomy for femoral arterial thrombosis after arterial catheterization. Pediatr Cardiol. 24(4):409-11. (2003)

・Miyazawa R, Ikeuchi Y, Tomomasa T, Ushiku H, Ogawa T, Morikawa A. Determinants of prognosis of acute transverse myelitis in children. Pediatr Int. 45(5):512-6. Review. (2003)

・Shimada A, Maruyama K, Shitara T, Kato M, Cho K, Kobayashi T, Fujiu T, Tsuchida Y, Nishida A, Hayashi Y, Minakami H, Kozawa K, Kimura H. Proinflammatory cytokinemia associated with transient myeloproliferative disorder in Down syndrome. Biol Neonate. 2004:85(3):167-72. (2003)

・Tomomasa T, Kobayashi A, Kaneko H, Mika S, Maisawa S, Chino Y, Syou H, Yoden A, Fujino J, Tanikawa M, Yamashita T, Kimura S, Kanoh M, Sawada K, Morikawa A. Granulocyte adsorptive apheresis for pediatric patients with ulcerative colitis. Dig Dis Sci. 48(4):750-4. (2003)

・Tamura K, Suzuki M, Arakawa H, Tokuyama K, Morikawa A. Linkage and association studies of STAT6 gene polymorphisms and allergic diseases. Int Arch Allergy Immunol. 131(1):33-8. (2003)

・Kato M, Minakami H, Kuroiwa M, Kobayashi Y, Oshima S, Kozawa K, Morikawa A, Kimura H. Superoxide radical generation and Mn- and Cu-Zn superoxide dismutases activities in human leukemic cells. Hematol Oncol. 21(1):11-6. (2003)

・Suzuki M, Kato M, Kimura H, Fujiu T, Morikawa A. Inhibition of human eosinophil activation by a cysteinyl leukotriene receptor antagonist (pranlukast: ONO-1078). J Asthma. 40(4):395-404.(2003)

・Todokoro M, Mochizuki H, Tokuyama K, Morikawa A. Childhood cough variant asthma and its relationship to classic asthma. Ann Allergy Asthma Immunol. 90(6):652-9. (2003)

・Takizawa T, Kato M, Suzuki M, Tachibana A, Motegi Y, Fujiu T, Kimura H, Arakawa H, Mochizuki H, Tokuyama K, Morikawa A. Distinct isoforms of protein kinase C are involved in human eosinophil functions induced by platelet-activating factor. Int Arch Allergy Immunol. 131 Suppl 15-9. (2003)

・Suzuki M, Kato M, Hanaka H, Izumi T, Morikawa A. Actin assembly is a crucial factor for superoxide anion generation from adherent human eosinophils. J Allergy Clin Immunol. 112(1):126-33. (2003)

・Kobayashi Y, Arakawa H, Suzuki M, Takizawa T, Tokuyama K, Morikawa A. Polymorphisms of interleukin-4–related genes in Japanese children with minimal change nephrotic syndrome. Am J Kidney Dis. 42(2):271-6. (2003)

・Watanabe M, Ono S, Tomomasa T, Okada Y, Kobayashi T, Suzuki T, Morikawa A. Measurement of tricuspid annular diastolic velocities by Doppler tissue imaging to assess right ventricular function in patients with congenital heart disease. Pediatr Cardiol. 24(5):463-7. (2003)

・Okada Y, Shinohara M, Kobayashi T, Inoue Y, Tomomasa T, Kobayashi T, Morikawa A. Gunma Kawasaki Disease Study Group. Effect of corticosteroids in addition to intravenous gamma globulin therapy on serum cytokine levels in the acute phase of Kawasaki disease in children. J Pediatr. 143(3):363-7. (2003)

・Shiojima T, Ohki Y, Nako Y, Morikawa A, Okubo T, Iyobe S. Immediate control of a methicillin-resistant Staphylococcus aureus outbreak in a neonatal intensive care unit. J Infect Chemother. 9(3):243-7. (2003)

・Morikawa A. Greetin from the President. International Journal Pediatric Otorhinolaryngology67:1267 (2003)

・Mochizuki H,Morikawa A. Airway inflammation in children with a chronic cough. International Journal Pediatric Otorhinolaryngology67:1267-1268 (2003)

2002

・Tachibana A, Kimura H, Kato M, Nako Y, Kozawa K, Morikawa A. Respiratory syncytial virus enhances the expression of CD11b molecules and the generation of superoxide anion by human eosinophils primed with platelet-activating factor. Intervirology. 45(1):43-51. (2002)

・Hashimoto M,Nishida A,Minakami H,Takashima Y,Kato M,Okada Y,Ogawa Y,Itoh S,Kimura H. Decreased expression of L-selectin on peripheral blood polymorphonuclear leukocytes in neonates with severe asphyxia. Biol Neonate 81:95-98 (2002)

・Hosoya M,Ushiku H,Arakawa H,Morikawa A. Low-voltage activity in EEG during acute phase of encephalitis predicts unfavorable neurological outcome. Brain Dev 24(3):161-5 (2002)

・Imashuku S,Teramura T,Ishi E,Kinugawa N,Kato M,Sako M,Kuriyama K,Hibi S. Intravenous immunoglobulin for hemophagocytic lymphohistiocytosis? J Clin Oncol 20(2):599-601 (2002)

・Kato M,Tachibana A,Kimura H,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Respiratory syncytial virus enhances expression of CD11b molecules and the generation of superoxide anion by human eosinophil primed with platelet-activating factor. Int Arch Allergy Immunol 128(S1):26 (2002)

・Maruyama K,Shinohara M,Hatakeyama S,Onigata K. Distal renal tubular acidosis associated with hypercalcemia and nephrocalcinosis in an infant. Pediatr Nephrol 17(11):977-978 (2002)

・Milla PJ,Cucchiara S,DiLorenzo C,Rivera NM,Rudolph C,Tomomasa T. Motility disorders in childhood: Working Group Report of the First World Congress of Pediatric Gastroenterology,Hepatology,and Nutrition. J Pediatr Gastroenterol Nutr 35 Suool 2:S187-95 (2002)

・Morikawa A. Pediatric bronchial asthma : A personal view. Current advances in pediatric asthma and other allergic Diseases. pp3-8 Jomo Newspaper Co (Maebashi) 2002

・Mochizuki H,Morikawa A. Ozone-induced airway damage and bronchial hyperresponsiveness. Current advances in pediatric asthma and other allergic Diseases. pp49-54 Jomo Newspaper Co (Maebashi) (2002)

・Kato M,Tachibana A,Kimura H,Morikawa A. Bronchial asthma and bronchiolitis induced by respiratory syncytial virus: role of eosinophils. In: Morikawa A Current advances in pediatric asthma and other allergic diseases. pp59-64 Jomo Newspaper Co (Maebashi) 2002

・Tokuyama K,Arakawa H,Yokoyama T,Ohki Y. Evaluation of allergic airway inflammation in immature animals.-A bacic approach to cure asthmatic children. Current advances in pediatric asthma and other allergic diseases. pp99-103 Jomo Newspaper Co (Maebashi) (2002)

・Arakawa H,Tamura K,Suzuki M. Novel dinucleotide repeat polymorphism in the first exon of the STAT6 gene is associated with allergic diseases. Current advances in pediatric asthma and other allergic diseases. pp127-132 Jomo Newspaper Co (Maebashi) 2002

・Shinohara M,Sone K,Kobayashi T,Tomomasa T,Morikawa A. Treatment of Kawasaki disease with predonisolone. Current advances in Pedeatric asthma and other allergic diseases pp163-167 Jomo Newspaper Co (Maebashi) (2002)

・Morita Y,Kimura H,Minakami H,Saitoh M,Kato M,Nagai A,Kozawa K. Acid-fast bacteria in the gastric contents of a neonate. Pediatr Infect Dis J. 21:987-988

・Nishimura H,Tokuyama K,Arakawa H,Ohki Y,Sato A,Kato M,Mochizuki H,Morikawa A. Airways responsiveness and airway remodeling after chronic exposure to procaterol and fenoterol in guinea pigs in vivo. Int Ahch Allergy Immunol 129:320-326 (2002)

・Ogawa T,Tomomasa T,Morikawa A. Developmental changes in cyclo-oxygenase mRNA induction by hypoxia in rat kidney. Pediatr Int 44(6):675-679 (2002)

・Okada Y,Fukasawa N,Tomomasa T,Inoue Y,Morikawa A. Atlanto-axial subluxation (Grisel’s sysndrome) associated with mumps. Pediatr Int 200 :44:192-194 (2002)

・Rappold GA,Fukami M,Niesler B,Schiller S,Zumkeller W,Bettendorf M,Heinrich U,Vlachopapadoupoulou E,Reinehr T,Onigata K,Ogata T. Deletions of the homeobox gene SHOX (short stature homeobox) are an important cause of growth failure in children with short stature. J Clin Endocrinol Metab 87(3):1402-6 (2002)

・Shimoda M,Morita S,Obata Y,Sotomaru Y,Kono T,Hatada I. Imprinting of a small nucleolar RNA gene on mouse chromosome 12. Genomics 79(4):483-486 (2002)

・Uemura A,Takizawa T,Ochiai W,Ynagagisawa M,Nakashima K,Taga T. Cardiortophin-like cytokine induces astrocyte differentiation of fetal neuroepithelial cells via activation of stat3. Cytokine 18(1):1-7 (2002)

・Yamanouchi H,Yokoo H,Yuhara Y,Maruyama K,Sasaki A,Hirato J,Nakazato Y. An autopsy case of ornithine transcarbamylase deficiency. Brain Dev 24(2):91-4

・Yoshiuchi I,Yamagata K,Zhu Q,Tamada I,Takahashi Y,Onigata K,Takeda J,Miyagawa J,Matsuzawa Y. Identification of a gain-of-function mutation in the HNF-1β gene in a Japanese family with MODY. Diabetologia 45(1):154-5 (2002)

・Mochizuki H, Ohki Y, Arakawa H, Kato M, Tokuyama K, Morikawa A. Effect of inhaled indomethacin on distilled water-induced airway epithelial cell swelling. J Appl Physiol. 92(1):155-61. (2002)

・Ohki Y, Tokuyama K, Sato A, Nishimura H, Tabata M, Tomiyoshi K, Inoue T, Arakawa H, Kato M, Mochizuki H, Morikawa A. Maturational changes in airway remodeling after chronic exposure to ovalbumin in sensitized guinea pigs: role of cell renewal of airway resident cells. Pediatr Res 52(4):525-32. (2002)

・Miyazawa R, Tomomasa T, Kaneko H, Tachibana A, Ogawa T, Morikawa A. Prevalence of gastro-esophageal reflux-related symptoms in Japanese infants. Pediatr Int. 44(5):513-6.

・Maruyama K, Watanabe H, Onigata K
Reversible secondary pseudohypoaldosteronism due to pyelonephritis. Pediatr Nephrol. 17(12):1069-70. (2002)

・Kato M, Kimura H, Motegi Y, Tachibana A, Minakami H, Morikawa A, Kita H. Platelet-activating factor activates two distinct effector pathways in human eosinophils. J Immunol. 169(9):5252-9. (2002)

・Tachibana A, Kato M, Kimura H, Fujiu T, Suzuki M, Morikawa A. Inhibition by fenoterol of human eosinophil functions including beta2-adrenoceptor-independent actions. Clin Exp Immunol. 130(3):415-23. (2002)

・Ogawa T, Tomomasa T, Morikawa A. Developmental changes in cyclo-oxygenase mRNA induction by hypoxia in rat kidney. Pediatr Int. 44(6):675-9. (2002)

・Tonooka N, Tomura H, Takahashi Y, Onigata K, Kikuchi N, Horikawa Y, Mori M, Takeda J
High frequency of mutations in the HNF-1alpha gene in non-obese patients with diabetes of youth in Japanese and identification of a case of digenic inheritance. Diabetologia. 45(12):1709-12. (2002)

・Inoue Y, Kato M, Ohsuka T, Morikawa A. Successful treatment of a child with inferior vena cava thrombosis using a temporary inferior vena cava filter. Pediatr Cardiol. 23(1):74-6. (2002)

・Inoue Y, Tomomasa T, Okada Y, Morikawa A. Divided right atrium associated with extensive coronary vein abnormalities. Pediatr Cardiol. 23(1):68-70. (2002)

・Arakawa H, Takizawa T, Tokuyama K, Mochizuki H, Morikawa A. Efficacy of inhaled anticholinergics and anesthesia in treatment of a patient in status asthmaticus. J Asthma. 39(1):77-80. (2002)

・Tomomasa T,Ogawa T,Hikima A,Tabata M Kaneko H,Morikawa A
Developmental changes in cyclooxygenase mRNA expression in the gastric mucosa of rats. J Pediatr Gastroenterol Nutr. 34(2):169-73. (2002)

・Harigaya A,Nako Y,Morikawa A,Okano H,Takagi T. Premature infant with severe periventricular leukomalacia associated with a large placental chorioangioma: a case report. J Perinatol. 22(3):252-4.

・Okamoto M,Nako Y,Tachibana A,Fujiu T,Ohki Y,Tomomasa T,Morikawa A. Efficacy of phenytoin against hyponatremic seizures due to SIADH after administration of anticancer drugs in a neonate. J Perinatol. 22(3):247-8. (2002)

・Tokuyama K, Nishimura H, Iizuka K, Kato M, Arakawa H, Saga R, Mochizuki H, Morikawa A. Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo. Pharmacology. 64(4):189-95.

・Mirza ZN, Kato M, Kimura H, Tachibana A, Fujiu T, Suzuki M, Mochizuki H, Tokuyama K, Morikawa A. Fenoterol inhibits superoxide anion generation by human polymorphonuclear leukocytes via beta-adrenoceptor-dependent and -independent mechanisms. Ann Allergy Asthma Immunol. 88(5):494-500. (2002)

・Inoue Y, Tokuyama K, Nishimura H, Arakawa H, Kato M, Mochizuki H, Morikawa A. Effects of STA(2), a thromboxane A(2) mimetic, in inducing airflow obstruction and airway microvascular leakage in guinea pigs. Pharmacology. 65(2):62-8. (2002)

・Kowase T,Nakazato Y,Yoko-O H,Morikawa A,Kojima I. Immunohistochemical localization of growth factor-regulated channel (GRC) in human tissues. Endocr J. 49(3):349-55.

・Watanabe T, Tomomasa T, Kaneko H, Takahashi A, Tabata M, Hussain S, Morikawa A. Involvement of serotonin and nitric oxide in endotoxin-induced gastric motility changes in conscious rats. Dig Dis Sci. 47(6):1284-9.

・Fujiu T, Kato M, Kimura H, Tachibana A, Suzuki M, Nako Y, Morikawa A. Cellular adhesion is required for effector functions of human eosinophils via G-protein coupled receptors. Ann Allergy Asthma Immunol. 89(1):90-8. (2002)

・Takizawa T, Kato M, Kimura H, Suzuki M, Tachibana A, Obinata H, Izumi T, Tokuyama K, Morikawa A. Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor. J Allergy Clin Immunol. 110(2):241-8. (2002)

・Takada C, Kaneko H, Tomomasa T, Tsukada S, Kanazawa T, Sotomatsu M, Oshimoto K, Okamoto S, Asao T, Takahashi A, Morikawa A. Endosonographic diagnosis of pneumatosis cystoides intestinalis in infancy. Tech Coloproctol. 6(2):121-3. (2002)

・Mochizuki H, Morikawa A, Kurosawa M. Bronchial hyperresponsiveness in a patient with systemic mastocytosis. Respirology. 7(3):285-8. (2002)

・Honda S, Yamamoto K, Sekizuka M, Oshima Y, Nagai K, Hashimoto G, Kaneko H, Tomomasa T, Konno Y, Horiuchi R. Successful treatment of severe hyperammonemia using sodium phenylacetate powder prepared in hospital pharmacy. Biol Pharm Bull. 25(9):1244-6. (2002)

・Ohshima Y,Yamada A,Hiraoka M,Katamura K,Ito S,Hirao T,Akutagawa H,Kondo N,Morikawa A,Mayumi M. Early sensitization tu house dust mite is a major risk factor for subsequent development of bronchial asthma in Jaoanese infants with atopic dermatitis:results of a 4-year followup study. Ann Allergy Asthma Immunol89(3):265-270 (2002)

・Inoue Y,Shin SH,Ponikau JU,Kita H. The fungus,Alternaria,induces activation and degranulation of human eosinophils. J Allergy Clin Immunol 109:S165 (2002)

・Kato M,Suzuki M,Kimura H,Fujiu T,Tachibana A,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Activation of human eosinophils via G protein-coupled receptors: compared with neutrophils. J Allergy Clin Immunol 109:S324

・Suzuki M,Kato M,Kimura H,Tachibana A,Fujiu T,Arakawa H,Mochizuki H,Tokuyama K,Morikawa A. Inhibitory effect of pranlukast,a cysteinyl leukotriene receptor-anatagonist,on eosinophil activation induced by platelet-activating factor. J Allergy Clin Immunol 109:S225 (2002)

2001

・Kaneko H, Tomomasa T, Inoue Y, Kunimoto F, Fukusato T, Muraoka S, Gonmori K, Matsumoto T, Morikawa A. Amatoxin poisoning from ingestion of Japanese Galerina mushrooms. J Toxicol Clin Toxicol. 39(4):413-6. (2001)

・Kato M, Kephart GM, Morikawa A, Gleich GJ. Eosinophil infiltration and degranulation in normal human tissues: evidence for eosinophil degranulation in normal gastrointestinal tract. Int Arch Allergy Immunol. 125 Suppl 55-8. Review. (2001)

・Kimura H, Shibata Y, Minakami H, Hashizume S, Oba H, Sakaguchi M, Otsuki K, Kozawa K,Kato M. Release of IL-4 and IL-5 from human peripheral blood mononuclear cells co-cultured with Japanese cedar pollen antigen in vitro. Cell Biol Int. 25(8):841-4. (2001)

・Imashuku S,Kuriyama K,Teramura T,Ishi E,Kinugawa N,Kato M,Sako M,Hibi S. Requirement of etoposide in the treatment of Epstein-Barr virus-associated Hemophagocytic lymphohistiocytosis. J Clin Oncol 19:2665-2673 (2001)

・Koyama H,Harigaya A,Nako Y,Kohama Y,Morikawa A. Risk of neonatal complications in gestational diabetes. Kitakanto Med J 52(2):107-111 (2001)

・Miyamoto J,Hasegawa Y,Ohnami N,Onigata K,Kinoshita E,Nishi Y,Tachibana K,Hasegawa T. Development of growth hormone and adrenocorticotropic hormone deficiencies in patients with prenatal or perinatla-onset hypothalamic hypopituitarism having invisinble or thin pituitiary stalk on magnetic resonance imaging. Endocr J 48:355-62 (2001)

・Ogata T,Onigata K,Hotsubo T,Matsuo N,Rappold G. Growth hormone and gonadotropin-releasing hormone analog therapy in haploinsufficiency of SHOX. Endocr J. 48:317-22 (2001)

・Ochiai W,Ynagisawa M,Takizawa T,Nakashima K,Taga T. Astrocyte differentiation of fetal neuroepithelial cells involving cardiotrophin-1-induced activation of STAT3. Cytokine. 14:264-271 (2001)

・Saga R,Mochizuki H,Tokuyama K,Morikawa A. Relationship between bronchial hyperresponsiveness and development of asthma in wheezy infants. Chest 119(3):685-690 (2001)

・Takizawa T,Yanagisawa M,Ochiai W,Yasukawa K,Ishiguro T,Nakashima K,Taga T. Directly linked soluble IL-6 receptor-IL-6 fusion protein induces astrocyte differentiation from neuroepithelial cells via activation of STAT3. Cytokine. 13(5):272-279 (2001)

・Takizawa T,Nakashima K,Namihira M,Ochiai W,Uemura A,Yanagisawa M,Fujita N,Nakao M,Taga T. DNA methylation is a critical cell-intrinsic determinant of astrocyte differentiation in the fetal brain. Developmental Cell 1:749-758 (2001)

・Yanagisawa M,Takizawa T,Ochiai W,Uemura A,Nakashima K,Taga T. Fate alteration of neuroepithelial cells from neurogenesis to astrocytogenesis by bone morphogenetic proteins. Neurosci. Res 41:391-396 (2001)

・Yanagisawa M,Nakashima K,Takeda K,Ochiai W,Takizawa T,Ueno M,Takizawa M,Shibuya H,Taga T. Inhibition of BMP2-induced,TAK1 kinase-mediated neurite outgrowth by Smad6 and Smad7. Genes Cells 6:1091-1100 (2001)

・Yanagisawa M,Nakashima K,Takizawa T,Ochiai W,Arakawa H,Taga T. Signaling crosstalk underlying synergistic induction of astrocyte differenciation by BMPs and IL-6 family of cytokines. FEBS Lett 489:139-143 (2001)

・Matsuura N,Yokota Y,Kazahari K,Sasaki N,Amemiya S,Ito Y,Fukushima N,Koike A,Igarashi Y,Hirano T,Sugihara S,Miki Y,Urakami T,Uchigata Y,Kanematsu S,Ohki Y,Takesue M,Hasegawa Y,Miyamoto S,Fujimoto M,Fujitsuka S,Mori T,Ogawa H,Uchiyama M,Onigata K,Tachibana K,Kikuchi N,Taketani T,Kohno H,Kasahara Y,Isshiki G,Tokuda M,Takahashi T,Kanzaki S,Yokota I,KidaK,Okada T,Nishiyama S,Masuda H,Kinugasa A,Nukada O. The Japanese Study Group of Insulin Therapy for Childhood and AdolescentDiabetes (JSGIT): initial aims and impact of the family history of type 1diabetes mellitus in Japanese children. Pediatr Diabetes. 2(4):160-169. (2001)

・Kasahara M, Ohwada S, Takeichi T, Kaneko H, Tomomasa T, Morikawa A, Yonemura K, Asonuma K, Tanaka K, Kobayashi K, Saheki T, Takeyoshi I, Morishita Y. Living-related liver transplantation for type II citrullinemia using a graft from heterozygote donor. Transplantation. 15:71(1):157-9. (2001)

・Ohki Y, Kato M, Kimura H, Nako Y, Tokuyama K, Morikawa A. Elevated type IV collagen in bronchoalveolar lavage fluid from infants with bronchopulmonary dysplasia. Biol Neonate. 79(1):34-8. (2001)

・Nishigori H, Tomura H, Tonooka N, Kanamori M, Yamada S, Sho K, Inoue I, Kikuchi N, Onigata K, Kojima I, Kohama T, Yamagata K, Yang Q, Matsuzawa Y, Miki T, Seino S, Kim MY, Choi HS, Lee YK, Moore DD, Takeda J
Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A. 16:98(2):575-80.

・Nakashima K,Takizawa T,Ochiai W,Yanagisawa M,Hisatsune T,Nakafuku M,Miyazono K,KishimotoT,Kageyama R,Taga T
BMP2-madiated alteration in the developmenta pathway of fetal mouse brain cells from neurogenesis to astrocytogenesis. Proc Natl Acad Sci USA. 2001 98:5868-5873 (2001)

・Tamura K, Arakawa H, Suzuki M, Kobayashi Y, Mochizuki H, Kato M, Tokuyama K, Morikawa A
Novel dinucleotide repeat polymorphism in the first exon of the STAT-6 gene is associated with allergic diseases. Clin Exp Allergy. 31(10):1509-14. (2001)

・Miyazawa R, Hikima A, Takano Y, Arakawa H, Tomomasa T, Morikawa A
Plasmapheresis in fulminant acute disseminated encephalomyelitis. Brain Dev. 23(6):424-6. (2001)

・Takahashi A, Suzuki N, Ikeda H, Kuroiwa M, Tomomasa T, Tsuchida Y, Kuwano H
Results of bowel plication in addition to primary anastomosis in patients with jejunal atresia. J Pediatr Surg. 36(12):1752-6. (2001)

・Mochizuki H, Shigeta M, Morikawa A
Development of bronchial hyperresponsiveness during childhood. J Asthma. 38(1):1-21. Review. (2001)

・Takizawa T, Arakawa H, Tokuyama K, Morikawa A
Identification of allergen fractions of wheat flour responsible for anaphylactic reactions to wheat products in infants and young children. Int Arch Allergy Immunol. 125(1):51-6. (2001)

・Tomomasa T, Kobayashi K, Kaneko H, Shimura H, Fukusato T, Tabata M, Inoue Y, Ohwada S, Kasahara M, Morishita Y, Kimura M, Saheki T, Morikawa A
Possible clinical and histologic manifestations of adult-onset type II citrullinemia in early infancy. J Pediatr. 138(5):741-3. (2001)

・Kaneko H, Tomomasa T, Watanabe T, Takahashi A, Tabata M, Hussein S, Morikawa A. Effect of vincristine on gastric motility in conscious rats. Dig Dis Sci. 46(5):952-9. (2001)

・Nako Y, Tachibana A, Fujiu T, Tomomasa T, Morikawa A. Neonatal thrombocytosis resulting from the maternal use of non-narcotic antischizophrenic drugs during pregnancy. Arch Dis Child Fetal Neonatal Ed. 84(3):F198-200 (2001)

・Nishimura H, Mochizuki H, Tokuyama K, Morikawa A. Relationship between bronchial hyperresponsiveness and development of asthma in children with chronic cough. Pediatr Pulmonol. 31(6):412-8.

・Okada Y, Kato M, Minakami H, Inoue Y, Morikawa A, Otsuki K, Kimura H. Reduced expression of flice-inhibitory protein (FLIP) and NFkappaB is associated with death receptor-induced cell death in human aortic endothelial cells (HAECs). Cytokine. 21:15(2):66-74.(2001)

・Inoue Y, Kimura H, Kato M, Okada Y, Morikawa A. Sera from patients with Kawasaki disease induce intercellular adhesion molecule-1 but not Fas in human endothelial cells. Int Arch Allergy Immunol. 125(3):250-5. (2001)

・Kono M, Mochizuki H, Arakawa H, Kato M, Tokuyama K, Morikawa A. Age-dependent relationship between bronchial hyperresponsiveness to methacholine and total serum IgE level in asthmatic children. Ann Allergy Asthma Immunol. 87(1):33-8. (2001)

・Nagashima T, Murakami M, Onigata K, Morimura T, Nagashima K, Mori M, Morikawa A. Novel inactivating missense mutations in the thyrotropin receptor gene in Japanese children with resistance to thyrotropin. Thyroid. 11(6):551-9 (2001)

・Tomomasa T,Ogawa T, Hikima A, Kobayashi Y, Nakano K, Fukabori Y, Morikawa A. Developmental changes in cyclooxygenase mRNA expression in the kidney of rats. Pediatr Nephrol. 16(8):618-622. (2001)

・Nishimura H, Tokuyama K, Inoue Y, Arakawa H, Kato M, Mochizuki H, Morikawa A. Acute effects of prostaglandin D2 to induce airflow obstruction and airway microvascular leakage in guinea pigs: role of thromboxane A2 receptors. Prostaglandins Other Lipid Mediat. 66(1):1-15. (2001)

・Koike H, Motooka M, Kanda T, Onigata K, Murakami M, Suzuki T, Kobayashi I. Detection of point mutation for human growth hormone in patients with anti-pituitary antibody positive type 1 diabetes mellitus. J Int Med Res. 29(5):397-408. (2001)

・Takahashi A, Tomomasa T, Kaneko H, Watanabe T, Tabata M, Morikawa H, Tsuchida Y, Kuwano H. Intestinal motility in an in vivo rat model of intestinal ischemia-reperfusion with special reference to the effects of nitric oxide on the motility changes. J Pediatr Gastroenterol Nutr. 33(3):283-8. (2001)

・Morikawa A,Maeda S,Shigeta M,Arakawa H,Tamura H,Kato M,Tokuyama K,Kuroume T. Low Molecular Weight Fraction of Dermatophagoides Farinae is Present in Sera of Patients with Bronchial Asthma. The Kitakanto Medical Journal51(4):255-259 (2001)

・Okada Y,Ono S,Tomomasa T,Inoue Y,Morikawa A. Balloon angioplasty in a patient with Kabuki Make-up syndrome. Pediatrics International43:694-696 (2001)

・Kimura H,Shibata Y,Minakami H,Hashizume S,Oba H,Sakaguchi M,Otsuki K,Kozawa K,Kato M. Release Of IL-4 and IL-5 from Human Peripheral Blood Mononuclear Cells Co-Cultured with Japanese Cedar Pollen Antigen in Vitro. Cell Biology International25(8):841-844 (2001)

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